Basic information
Biomarker: miRNA150-5P
Histology type: endometrial carcinoma
Cohort characteristics
Region: Shatby Alexandria
Followed up time :
Subgroup 1 name : un-intervened endometrial cancer
Subgroup 1 number: 36
Subgroup 2 name: healthy controls
Subgroup 2 number: 36
Cohort statistics: Mean (SD);Range
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 72 | un-intervened endometrial cancer | 36 | healthy | 36 |
Sample information
Description: MiRNA150-5P can be suggested as promising biomarkers of endometrial cancer possibly part of a miRNA panel for management.
Sample type : serum
Sample method: RT-qPCR
Expression pattern : circulating overexpression cut off= 1.02
Expression elevation: Relative quantifcation miRNA expression in patients ΔΔCt: is the diference of ΔCt value between the cases and the average of control (ΔΔCt=ΔCt cases – average ΔCt control). The relative quantifcation of miRNA expression was presented as the fold change normalized to the spike in reference mirna 39 and relative to the healthy control samples. Relative quantifcation miRNA expression in healthy control=2–ΔΔCt ΔCt = Ct (target miRNA) − Ct (reference miRNA) ΔΔCt = ΔCt of control − average ΔCt of control
Disease information
Subgroup 1 age: 57.6 ± 8.3
Subgroup 2 age: 53.7±9.4
