Basic information
Biomarker: CCAT1
Histology type: endometrial carcinoma
Cohort characteristics
Country: Germany
Region: Regensburg
Followed up time :
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 100 | EEC | 61 | normal endometrium | 39 |
Sample information
Description: Given that the lncRNA CCAT1 was found to be overexpressed in endometrial cancer, affected the growth of HEC-1B cells and the expression of growth regulatory genes, our data suggest CCAT1 to exert oncogenic functions in endometrial cancer and encourage further studies to examine to what extent this lncRNA might be a potential therapy target in this cancer entity.
Sample type : tissue
Sample method: RT-PCR
Expression pattern : overexpression
Validation in cell line : HEC-1B and RL95/2 endometrial adenocarcinoma cells
Validation in cell method : siRNA transfection and proliferation studies, GeneChip microarray assay,Western blot analysis
Disease information
Related information
Funtion description: lncRNA CCAT1 was found to be overexpressed in endometrial cancer, affected the growth of HEC-1B cells and the expression of growth regulatory genes
