Basic information

Biomarker: CCAT1

Histology type: endometrial carcinoma

Cohort characteristics

Country: Germany

Region: Regensburg

Followed up time :

Total number Group I Group I number Group II Group II number Group III Group III number Group IV Group IV number
100 EEC 61 normal endometrium 39

Sample information

Description: Given that the lncRNA CCAT1 was found to be overexpressed in endometrial cancer, affected the growth of HEC-1B cells and the expression of growth regulatory genes, our data suggest CCAT1 to exert oncogenic functions in endometrial cancer and encourage further studies to examine to what extent this lncRNA might be a potential therapy target in this cancer entity.

Sample type : tissue

Sample method: RT-PCR

Expression pattern : overexpression

Validation in cell line : HEC-1B and RL95/2 endometrial adenocarcinoma cells

Validation in cell method : siRNA transfection and proliferation studies, GeneChip microarray assay,Western blot analysis

Disease information

Related information

Funtion description: lncRNA CCAT1 was found to be overexpressed in endometrial cancer, affected the growth of HEC-1B cells and the expression of growth regulatory genes

Visulization