Basic information
Biomarker: miR-27a
Histology type: endometrioid endometrial carcinoma
Cohort characteristics
Country: China
Region: Shangha
Study type: retrospective case-control analysis
Followed up time :
Subgroup 1 name : Discovery phase
Subgroup 1 number: 29
Subgroup 2 name: validated
Subgroup 2 number: 64
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 93 | Discovery phase | 29 | validated | 64 |
Sample information
Description: miR-27a and CA125, demonstrated a high accuracy in the diagnosis of EEC and might serve as a novel non-invasive biomarker in the future.
Sample type : plasma
Sample method: quantitative real-time PCR
Disease information
Related information
Expression figure legend: ROC curve analysis for miR-15b (A), -27a (B), -223 (C), CA125 (D), and the panel (E).
Expression figure link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203829/figure/pone-0110767-g002/
HGNC miRNA approved symbol: MIR27A
HGNC miRNA approved name: microRNA 27a
HGNC miRNA locus type: RNA, micro
HGNC miRNA symbol status: Approved
HGNC miRNA ID: HGNC:31613
HGNC miRNA link: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:31613
Stem loop sequence symbol: hsa-mir-27a
Stem loop sequence accession: MI0000085
Stem loop sequence gene family: MIPF0000036
Stem loop sequence annotation confidence: high
Mature sequence symbol: hsa-miR-27a-5p $hsa-miR-27a-3p
Mature sequence accession: MIMAT0004501$ MIMAT0000084
Previous IDs: hsa-miR-27a*$ hsa-miR-27a
Evidence: experimental; cloned[PMID:17604727]$ experimental; cloned [PMID:11679670,PMID:15325244,PMID:17604727,PMID:17616659], Northern [PMID:11679670]
miRBase link: https://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0000085
