Basic information
Biomarker: UCA1
Histology type: endometrial carcinoma
Cohort characteristics
Country: China
Region: Guangzhou
Followed up time :
Subgroup 1 name : Low
Subgroup 1 number: 33
Subgroup 2 name: High
Subgroup 2 number: 12
Cohort statistics: cutoff<55;cutoff>55
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 60 | EC | 45 | proliferative endometrium | 15 |
Sample information
Description: Our findings provide the convincing evidence that the UCA1 plays an important role in the metastasis of EC and may serve as a novel molecular marker to predict the aggressive tumor progression and unfavorable prognosis of EC patients.
Sample type : tissue
Sample method: QRT-PCR
Expression pattern : high expression(, the median fold change of UCA1 was used as a cutoff value)
Validation in cell line : human EC cell lines HTB-111 and Ishikawa
Validation in cell method : UCA1 siRNAs transfection,Scratch wound healing assay,Cell migration assay,
Disease information
Cohort age: 24;21
Subgroup 1 age: 18;15
Subgroup 2 age: 6;6
