Basic information
Biomarker: miR-944
Histology type: endometrial carcinoma
Cohort characteristics
Country: China
Region: Guangxi
Followed up time :
Subgroup 1 name : High
Subgroup 1 number: 34
Subgroup 2 name: Low
Subgroup 2 number: 34
Cohort statistics: cutoff<55;cutoff>55
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 88 | EC | 68 | normal endometrial tissues | 20 |
Sample information
Description: MiR-944 acts as a prognostic marker and promotes the tumor progression in endometrial cancer
Sample type : tissue
Expression pattern : overexpression
Validation in cell line : Human EC cell lines (HEC-1-B, AN3CA and KLE)
Validation in cell method : Real-time quantitative PCR,Proliferation assay,Flow cytometer detection for cell cycle and apoptosis,Luciferase reporter assay,Western blotting
Validation in animal model : Six-week-old female athymic BALB/c nude mice
Disease information
Cohort age: 30;38
Subgroup 1 age: 14;20
Subgroup 2 age: 16;18
Related information
HGNC miRNA approved symbol: MIR944
HGNC miRNA approved name: microRNA 944
HGNC miRNA locus type: RNA, micro
HGNC miRNA symbol status: Approved
HGNC miRNA ID: HGNC:33690
HGNC miRNA link: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:33690
Stem loop sequence symbol: hsa-mir-944
Stem loop sequence accession: MI0005769
Stem loop sequence gene family: MIPF0000541
Stem loop sequence annotation confidence: not enough data
Mature sequence symbol: hsa-miR-944
Mature sequence accession: MIMAT0004987
Evidence: experimental; cloned [PMID:17616659]
miRBase link: https://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0005769
