Basic information

Biomarker: LINC01133

Histology type: endometrial carcinoma

Cohort characteristics

Country: China

Region: Tianjin

Followed up time :

Total number Group I Group I number Group II Group II number Group III Group III number Group IV Group IV number

Sample information

Description: We demonstrated that LINC01133 expression are associated with EC development and progression. Our findings suggest a potential role for these lncRNAs as novel EC biomarkers.

Expression pattern : expression

Validation in cell line : Ishikawa (estrogen receptor α-positive) and HEC-1-A (estrogen receptor α-negative) human EC cell lines

Validation in cell method : RT-qPCR,Cell proliferation assay (CCK-8 assay),Flow cytometry analysis of cell cycle distribution,Annexin V-FITC/PI double staining and flow cytometry,Transwell invasion assay,Scratch migration assay,

Disease information

Related information

Funtion description: Through siRNA knockdown of these two lncRNAs, the auther observed decreased viability, cell cycle arrest, and increased apoptosis in two EC cell lines. Using the Transwell and scratch assays, the auther found decreased migration and invasiveness, respectively, of the two EC cell lines.

Visulization