Basic information
Biomarker: metallothioneins
Histology type: endometrial carcinoma
Stage: high risk
Cohort characteristics
Country: Greece
Region: Ioannina
Followed up time :
Subgroup 1 name : negative
Subgroup 1 number: 8
Subgroup 2 name: positive
Subgroup 2 number: 28
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 155 | EC | 89 | hyperplasia | 34 | normal endometrium | 32 |
Sample information
Conclusion: These data suggest that MT expression seems to be under hormonal control in normal endometrium; that it may modify p53 expression; and that it could be used as an additional biological marker indicating aggressive behaviour in endometrial lesions.
Sample type : tissue
Sample method: immunohistochemistry
Expression pattern : expression
Expression elevation: Immunostaining (nuclear or cytoplasmic) was calculated as the percentage of positive cells in relation to the total number of cells encountered in ten representative high-power ®elds. Every stained nucleus was considered positive, irrespective of intensity.
Disease information
Related information
UniProt Link:
Molecular function from UniProt:
