Basic information
Biomarker: telomerase
Histology type: endometrioid endometrial carcinoma
Cohort characteristics
Country: Germany
Region: Kiel
Followed up time :
Subgroup 1 name : telomerase activity positive
Subgroup 1 number: 50
Subgroup 2 name: telomerase activity negative
Subgroup 2 number: 3
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 53 | EC | 53 |
Sample information
Conclusion: It is concluded that beyond a link to proliferation, high telomerase activity reflects a deregulation of the cell cycle associated with an increased rate of cells entering S phase and a higher degree of malignancy. Therefore, quantitative analysis of telomerase activity may be useful for identifying EC patients at high risk for recurrence.
Sample type : tissue
Sample method: Southern blot analysis/immunohistochemical/PCR/elomeric repeat amplification protocol (TRAP)
Expression pattern : High activity
Disease information
Statictics: Median;Range
Cohort age: 63;29-86
Related information
UniProt Link:
Molecular function from UniProt:
