Basic information
Biomarker: S100
Histology type: endometrial carcinoma
Stage: low risk
Cohort characteristics
Country: Germany
Region: Wuerzburg
Followed up time :
Subgroup 1 name : S100+DC/mm2>10
Subgroup 1 number: 44
Subgroup 2 name: S100+DC/mm2<10
Subgroup 2 number: 71
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 115 | less than 10 S100+DC/mm2 | 44 | 10 or more S100+ DC/mm2 | 71 |
Sample information
Conclusion: S100 as an immunohistochemically-detected marker with prognostic significance in endometrial carcinoma. Our results indicate that the immunohistochemical determination of S100+ DC could contribute to the identification of a high-risk subgroup and, therefore, would be a favorable prognostic factor for endometrial carcinoma.
Sample type : tissue
Sample method: immunohistochemistry
Expression pattern : S100+ DC/mm2>10
Expression elevation: group 1: less than 10 S100+DC/mm2 (n = 44) and group 2: 10 or more S100+ DC/mm2
Disease information
Related information
UniProt Link: https://www.uniprot.org/uniprotkb?query=S100
Molecular function from UniProt:
HPA link: https://www.proteinatlas.org/search/S100
HGNC link: https://www.genenames.org/tools/search/#!/?query=S100
