Basic information
Biomarker: RFP
Histology type: endometrial carcinoma
Cohort characteristics
Country: Japan
Region: Nagoya
Followed up time :
Subgroup 1 name : negative
Subgroup 1 number: 62
Subgroup 2 name: positive
Subgroup 2 number: 57
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 119 | endometrial endometrioid adenocarcinoma |
Sample information
Conclusion: Positive RFP expression is a predictive marker for an unfavorable clinical outcome in patients with endometrial cancer.
Sample type : tissue
Sample method: Immunohistochemistry
Expression pattern : expression(+)
Expression elevation: When greater than 10% of the tumor cells were stained with the antibody regardless of staining intensity, the specimen was categorized as positive for RFP expression.
Disease information
Statictics: Median;Range
Cohort age: 57; 27 - 81
Related information
Funtion description: RFP knockdown significantly impaired cancer cell migration and invasion in vitro with concomitant decreases of integrins beta1 and alpha2.
UniProt Link: https://www.uniprot.org/uniprotkb?query=Ret%20finger%20protein
Molecular function from UniProt:
HPA link: https://www.proteinatlas.org/search/Ret+finger+protein
HGNC link: https://www.genenames.org/tools/search/#!/?query=Ret%20finger%20protein
