Basic information
Biomarker: CD44v6
Histology type: endometrial carcinoma
Cohort characteristics
Followed up time :
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 57 | EC | 47 | proliferative endometrium samples | 10 |
Sample information
Conclusion: Our findings suggest that fascin might be an independent prognostic indicator in the different steps of extracellular matrix invasion.
Sample type : tissue
Sample method: immunohistochemisty
Expression pattern : IHS ≥ 11
Expression elevation: The extent of positively stained epithelial cells was estimated and classified on a four-point scale as follows: no staining = 0%, 1 = 1%–10%, 2 = 11%–25%, 3 = 26%–50%, and 4 = 51%–100%. The intensity of the immunoexpression was categorised into three groups: weak (+1), moderate (+2), and strong (+3). A final IHS score was obtained by multiplying the score for extent and the score for intensity. Therefore, the combined immunoreactivity score ranged from 0 to 12. According to this, cases were categorised into three groups: 0 (absent), IHS ≤ 10, and IHS ≥ 11.
Disease information
Related information
UniProt Link:
Molecular function from UniProt:
Expression figure legend: Immunohistochemical staining for fascin.
