Basic information
Biomarker: ProExC
Histology type: rare type
Cohort characteristics
Country: Egypt
Region: Tanta
Study type: retrospective study
Followed up time :
Subgroup 1 name : positive in EAC
Subgroup 1 number: 8
Subgroup 2 name: negative in EAC
Subgroup 2 number: 2
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 30 | endometrial adenocarcinoma | 20 | endocervical adenocarcinoma | 10 |
Sample information
Conclusion: ProExC is a novel immunohistochemical marker for differentiating ECA from EMA and its inclusion in a panel of immunohistochemical markers including p16, ER, PR, and vimentin is recommended when there is morphological and clinical doubt as to the primary site of endocervical or endometrial origin.
Sample type : tissue
Sample method: immunohistochemistry
Expression pattern : positive(>5% )
Expression elevation: For ProExC, the staining was scored as diffuse (>80%) strong (2), focal (5% to 80%) strong (1), or negative (0) based on the nuclear staining for ProExC . For ProExC, weak cytoplasmic staining or reactivity in <5% nuclei was interpreted as negative.
Disease information
Related information
UniProt Link:
Molecular function from UniProt:
