Basic information
Biomarker: PPH3
Histology type: endometrial stromal tumor
Stage: low grade
Cohort characteristics
Country: China
Region: Shanghai
Study type: retrospective study
Followed up time :
Subgroup 1 name : 0–21 group Recurrence/Number
Subgroup 1 number: 0/19
Subgroup 2 name: >21 group Recurrence/Number
Subgroup 2 number: 44990
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 24 | invasive endometrial stromal sarcomas | 24 |
Sample information
Conclusion: In this small study of WHO2003 defined ESS-LG, high levels of proliferation as measured by PPH3 are predictive of recurrence.
Sample type : tissue
Sample method: H&E stained,immunohistochemistry
Expression pattern : >21
Expression elevation: PPH3 expressions were defined as the total number of positive nuclei and mitoses in 10 HPF
Disease information
Related information
UniProt Link:
Molecular function from UniProt:
Expression figure legend: Examples of Endometrial Stroma Sarcomas showing parallel Ki-67 and PPH3 expression.
Expression figure link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795675/figure/pone-0075899-g002/
