Pubmed Biomarker Character Relation P-value Description
34339705 TMEFF2 TMEFF2 expression distant metastasis p=0.039 TMEFF2 expression was associated with distant metastasis
28453461 SerpinE2 high SerpinE2 expression distant metastasis p=0.013 high SerpinE2 expression was correlated with distant metastasis
27648714 L1CAM L1CAM positivity Extra-abdominal relapses p<0.0001 Extra-abdominal relapses were more frequent in L1CAM-positive (13.2%) than L1CAM-negative (1.9%) stage I endometrioid carcinomas
27549092 CA-125 increased serum CA-125 value adnexal invasion p=0.03 Adnexal involvements were related to increased serum CA-125 values
27549092 CA-125 increased serum CA-125 value cervical involvements Cervical involvements were related to increased serum CA-125 values
27549092 CA-125 mean pre-operative CA-125 values uterine serosa p=0.01 When the uterine serosa was involved by the tumor, the mean pre-operative CA-125 values were significantly higher when compared to women with no uterine serosal involvement
27540975 UCA1 High UCA1 expression distant metastasis p=0.003 High UCA1 expression was observed to be closely correlated with distant metastasis
27340318 IL-33 serum IL-33 distant metastases Serum IL-33 was close to the disease process: distant metastases
25964114 CA125 cutoff=30U/ml adnexal involement The best cutoff to evaluate adnexal involement in patients with clinical stage I was 30U/ml, with 81% sensitivity, and 78.4% specificity.
24420153 VEGF concentration metastases p=0.001 In the multivariable analysis, the concentration of VEGF was the sole independent, albeit weak predictive factor for the presence of metastases(OR= 1.004, 95% confidence interval, 1.002-1.007)
24420153 VEGF concentration serum concentration of VEGF metastases p<0.001 The serum concentration of VEGF was higher in the group with metastases than in the group without metastases (median [range], 743 pg/mL [546-1,183 pg/mL] vs. 383 pg/mL [31-1,524 pg/mL]
34339705 SMOC-2 SMOC-2 high expression distant metastasis p=0.039 SMOC-2 high expression was positively correlated with distant metastasis
23947899 CyclinD1 positive expression of CyclinD1 metastasis p<0.05 The ratio of positive expression of CyclinD1 was 47.0% in the non-metastatic and 67.0% in metastatic group
23947899 CyclinD1 CyclinD1 expression metastasis p<0.05 CyclinD1 expression was correlated with metastasis
23583212 HE4 and CA125 combination of HE4 and CA125 metastases p<.001 By a multivariate analysis, the combination of HE4 and CA125 (a risk score algorithm) was the only predictive factor for the presence of metastases.(OR= 21.562; 95% confidence interval, 5.472-84.963;)
23583212 HE4 and CA125 the serum concentrations of HE4 and CA125 metastases p=.001 The serum concentrations of HE4 were higher in the group with metastases than in the group without metastasesand. (median [interquartile range], 148.6 pmol/L [71.6-219.1 pmol/L] vs 77.2 pmol/L [52.9-99.3 pmol/L];
23583212 HE4 and CA125 the serum concentrations of CA125 metastases p<.001 The serum concentrations of CA125 were higher in the group with metastases than in the group without metastasesand.(20.0 U/mL [10.1-70.8 U/mL] vs 4.3 U/mL [2.9-10.4 U/mL])
23257935 ER-α36 ER-α36-negative cervical involvement p<0.05 ER-α36-negative tissues were significantly more likely than ER-α36-positive tumors to have tumor involvement of the cervix
23114646 EMT peritoneal cytology positive peritoneal cytology p<0.01 EMT status, which was represented by both reduced E-cadherin and nuclear expression of Snail, was significantly associated with positive peritoneal cytology .
22008707 ADCmin ADCmin cervical involvement p=0.003 There were significant correlations between the ADCmin of the primary tumor and cervical involvement
22008707 ADCmin ADCmin ovarian metastasis p<0.001 There were significant correlations between the ADCmin of the primary tumor and ovarian metastasis
22008707 ADCmin ADCmin peritoneal cytology p=0.027 There were significant correlations between the ADCmin of the primary tumor and peritoneal cytology
32901849 CDK9 CDK9 expression level metastatic p<0.001 The CDK9 expression level in primary endometrial cancer tissues was significantly lower than that in metastatic and recurrent endometrial cancer tissues. These differences were statistically significant (metastatic vs. primary,
20686370 YT521 YT521 exon6-retention mRNA expression metastasis p=0.026 YT521 exon6-retention mRNA expression was positively correlated to metastasis.(R = 0.196)
18313673 aquaporin-1 (AQP1) AQP1/IMD ratio metastasis The AQP1/IMD ratio was significantly higher for lesionsfrom the women with extrauterine metastasis than for thosewith no extrauterine metastasis
17065588 versican stromal versican expression ovarian metastasis p=0.024 Stromal versican expression was significantly higher in ovarian metastasis
12684410 KAI1 loss of KAI1 expression metastases p<0.001 Loss of KAI1 expression occurred in an increasing frequency (27.8-71.4%) from early stages of primary endometrial carcinomas to metastatic tumors
9038731 CA 72-4 serum CA72-4 positivity adnexal metastasis p<0.05 Serum CA72-4 positivity was correlated with depth of adnexal metastasis
9038731 CA 72-4 serum CA72-4 positivity adnexal metastasis. Multivariate analysis showed a significant correlation between serum CA72-4 positivity and adnexal metastasis.
7909788 EGFR EGFR-positive metastatic p<0.002 Seventy-seven percent of patients with metastatic disease were EGFR-positive versus 36% positivity in patients with no evidence of metastases
30591489 L1CAM L1CAM positivity distant metastasis p=0.01 Distant metastasis was significantly associated with L1CAM positivity
30556848 LncRNA FER1L4 Low expression of FER1L4 distant metastasis p=0.002 Low expression of FER1L4 was significantly correlated with distant metastasis
29984790 MACC1/c-Myc distal metastasis p<0.05 MACC1/c-Myc expression was correlated with distal metastasis
29096882 Asparaginase-like protein 1 metastatic p=0.001 ASRGL1 was more frequently lost in metastatic lesions than ERα (77% and 60% of lesions respectively
28800309 CA125 cut-off value =35 u/ml. metastasis the suitable cut-off value for CA125 in involvement of the ovaries (sensitivity = 77%, specificity = 72%, positive predictive value = 31%, negative predictive value = 95%) was 35 u/ml.
28800309 CA125 cut-off value = 35 u/ml. metastasis the suitable cut-off value for CA125 in omental involvement (sensitivity = 70%, specificity = 70%, positive predictive value = 22%, negative predictive value = 95%) was 35 u/ml.

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