Biomarker: Maltitol

Histology type: endometrial carcinoma

Country: China

Region: Guangzhou

Followed up time :

Description: It can combine the results of metabolomics and lncRNA sequencing to assist in the early diagnosis of endometrial precancerous lesions and endometrial cancer patients, to enhance the sensitivity and specificity of diagnosis, which has a certain clinical application prospect.

Sample method: LC-MS/MS technology

Status: Detected but not Quantified

HMDB ID: HMDB0002928

Secondary accession numbers: HMDB02928

Common name: Maltitol

Description: Maltitol is a sugar alcohol (polyol) used as a sugar substitute. It has 90% the sweetness of sugar and nearly identical properties, except for browning. It is used to very easily replace sugar and has less food energy, does not promote tooth decay and has a somewhat lower blood sugar response. Unfortunately, maltitol is well known to cause gastric distress, particularly if consumed in great quantities. Chemically, maltitol is also known as 4-O-alpha-Glucopyranosyl-D-sorbitol. Commercially, it is known under trade names such as Maltisorb and Maltisweet. Due to its slow absorption, excessive consumption of Maltitol can have laxative effect and often can cause gas and/or bloating. Maltitol is particularly demonized regarding gastric side effects because it is so easy for food producers to use it in vast quantities (due to its amazingly sugar-like properties) so consumers often end up consuming far more than they could most other sugar alcohols. While this is a major problem with maltitol, many sugar alcohols are far more likely to cause gastric distress than maltitol when compared gram-for-gram.

Chemical formula: C12H24O11

Chemical taxonomy description: Belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. Fatty acyl glycosides of mono- and disaccharides are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol.

Chemical taxonomy kingdom: Organic compounds

Chemical taxonomy super class: Lipids and lipid-like molecules

Chemical taxonomy class: Fatty Acyls

Chemical taxonomy sub class: Fatty acyl glycosides

Direct parent: Fatty acyl glycosides of mono- and disaccharides

Alternative parents: Alkyl glycosides O-glycosyl compounds Disaccharides Fatty alcohols Sugar alcohols Oxanes Secondary alcohols Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives

Substituents: Fatty acyl glycoside of mono- or disaccharide Alkyl glycoside Disaccharide Glycosyl compound O-glycosyl compound Fatty alcohol Sugar alcohol Oxane Secondary alcohol Acetal Organoheterocyclic compound Oxacycle Polyol Organooxygen compound Primary alcohol Hydrocarbon derivative Organic oxygen compound Alcohol Aliphatic heteromonocyclic compound

Molecular framework: Aliphatic heteromonocyclic compounds

Disposition: alpha-D-glucoside

Associated disorders diseases: None

KEGG compound ID: None

CPD link: None

Process: None

HMDB link: https://hmdb.ca/metabolites/HMDB0002928