Basic information
Biomarker: p21
Biomarker subtype: gene
Clinical application: prognosis(unfavorable)
Histology type: endometrioid endometrial carcinoma
Stage: stage I
Cohort characteristics
Country: Norway
Region: Stavanger
Followed up time : 66 months (1-209),
Protocol age: 66;37–94
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 224 | EC | 224 |
Sample information
Sample type : tissue
Clinical method: immunohistochemical /tissue microarrays,image cytometry/PCR
Expression pattern : low p21(<1%) , high survivin expression(>158) and high microsatellite instability
Expression elevation: The percentage of positive cells for p16 was determined.
Disease information
Statictics: Median;Range
Protocol age: 66;37–94
Related information
Description: We conclude that low p21 and high survivin expression are poor prognosis indicators in FIGO stage I endometrial endometrioid adenocarcinoma, especially when high microsatellite instability occurs.
