Basic information
Biomarker: SPAG9
Biomarker subtype: gene
Clinical application: diagnosis
Histology type: endometrial carcinoma
Stage: early stage
Cohort characteristics
Country: Turkey
Region: Ankara
Study type: prospective cross-sectional study
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 80 | EC | 50 | healthy group | 10 | benign diseases | 20 |
Sample information
Sample type : serum
Clinical method: ELISA
Expression pattern : expression
Disease information
Related information
Description: SPAG9 is positively expressed in endometrial cancer, and with a high humoral immune response in patients. It may serve as a new type of endometrial cancer markers for early detection, diagnosis and treatment
Approved symbol: SPAG9
Approved name: sperm associated antigen 9
Locus type: gene with protein product
HGNC ID: HGNC:14524
HGNC link: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14524
Symbol status: Approved
Alias symbols: HSS SYD1 KIAA0516 MGC14967 MGC74461 MGC117291 JLP PHET HLC4 FLJ13450 FLJ14006 FLJ26141 FLJ34602 CT89 JIP4 JIP-4 PIG6
OMIM: 605430
Omim link: https://www.omim.org/entry/605430
NCBI name: 9043
NCBI link: https://www.ncbi.nlm.nih.gov/gene/9043
Summary: This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in brain (RPKM 29.0), testis (RPKM 27.0) and 25 other tissues
Expression: Ubiquitous expression in brain (RPKM 29.0), testis (RPKM 27.0) and 25 other tissues
NCBI gene expression https://www.ncbi.nlm.nih.gov/gene/9043#gene-expression
PDB ID: P62330
PDB link: https://www.ebi.ac.uk/pdbe/entry/search/index/?searchParams=%7B%22q_uniprot%22:%5B%7B%22value%22:%22(O60271)%22,%22condition1%22:%22AND%22,%22condition2%22:%22Contains%22%7D%5D,%22resultState%22:%7B%22tabIndex%22:0,%22paginationIndex%22:1,%22perPage%22:%2210%22,%22sortBy%22:%22Sort%20by%22%7D%7D
