ECbiomarker

Pubmed	Biomarker	P-value	Description
34399708	rs1137101		Heterozygous genotype AG of SNP LEP-R c.668A>G (p.Gln223Arg, rs1137101) is statistically significantly less frequent in obese (BMI >30) women with EC than in lean controls (BMI < 25)
30374843	Autotaxin	p=0.0115	ATX expression levels were significantly higher in obese women (BMI ≥ 30) with endometrial cancer compared with obese women with normal endometrium
23438672	Visfatin	p<0.05	In univariate and multivariate logistic regression models, a positive association between EC and serum visfatin, BMI, waist-to-hip ratio, diabetes, and hypertension was evident
23200913	GRP78	p=0.042	Obesity (BMI ≥30 kg/m2) was observed in significantly more patients with tumoral GRP78 overexpression compared to those who did not (BMI <30 vs. ≥30, 74% vs. 62%,
26763250	None		A logistic regression model with variable selection to show that the odds of having a POLE mutation were decreased with age (OR (odds ratio) 0.94 (95% CI 0.9-0.99) per year), BMI (OR 0.92 (95% CI 0.84-0.98) per unit increase) and advanced Stage (OR 0.04 (95% CI 0-0.39) relative to Stage I).
17128692	None	p=0.04	Lower BMI was associated with high stage
17128692	None	p=0.04	Lower BMI was associated with HER-2/neu expression

34399708

rs1137101

Heterozygous genotype AG of SNP LEP-R c.668A>G (p.Gln223Arg, rs1137101) is statistically significantly less frequent in obese (BMI >30) women with EC than in lean controls (BMI < 25)

30374843

Autotaxin

p=0.0115

ATX expression levels were significantly higher in obese women (BMI ≥ 30) with endometrial cancer compared with obese women with normal endometrium

23438672

Visfatin

p<0.05

In univariate and multivariate logistic regression models, a positive association between EC and serum visfatin, BMI, waist-to-hip ratio, diabetes, and hypertension was evident

23200913

GRP78

p=0.042

Obesity (BMI ≥30 kg/m2) was observed in significantly more patients with tumoral GRP78 overexpression compared to those who did not (BMI <30 vs. ≥30, 74% vs. 62%,

26763250

None

A logistic regression model with variable selection to show that the odds of having a POLE mutation were decreased with age (OR (odds ratio) 0.94 (95% CI 0.9-0.99) per year), BMI (OR 0.92 (95% CI 0.84-0.98) per unit increase) and advanced Stage (OR 0.04 (95% CI 0-0.39) relative to Stage I).

17128692

None

p=0.04

Lower BMI was associated with high stage

17128692

None

p=0.04

Lower BMI was associated with HER-2/neu expression