Pubmed Sample type Biomarker Biomarker type Expression pattern Clinical application Application supplementary
34162378 serum HOMA-IR OTHERS upregulated treatment predicted poor response to progestin
36037113 serum miR-21 RNA upregulated prognosis unfavorable
25219463 serum ANXA2 protein upregulated prognosis recurrent
25219463 serum ANXA2 protein upregulated prognosis recurrent
25329674 plasma miR-27a RNA diagnosis
25423695 serum CA125 protein upregulated prognosis unfavorable
25544793 cytology ZEB1 DNA upregulated diagnosis predict the lymph node metastasis
25557364 cytology ARID1A protein downgulated diagnosis peritoneal washings to confirm malignancy
25731151 serum Ca125 protein upregulated prognosis unfavorable
25731151 serum Tag72 protein upregulated prognosis unfavorable
25964114 serum CA125 protein upregulated diagnosis evaluate adnexal involement, lymph node metastasis
26223178 serum HE4 protein upregulated diagnosis predictor in distinguishing the high-risk patients
36037113 serum miR-205 RNA upregulated prognosis unfavorable
26308071 serum PGI protein upregulated treatment therapeutic target
26350184 serum TATI protein upregulated prognosis recurrence and distant metastasis,
26607777 serum HE-4 protein upregulated diagnosis discriminating early and advanced stages
26607777 serum YKL-40 protein upregulated diagnosis discriminating early and advanced stages
26678075 serum STN protein upregulated prognosis unfavorable
26701889 serum NRP-1 protein upregulated prognosis predicator of metastatic
26925634 serum CA-125 protein upregulated diagnosis predicate myometrial Invasion
27039795 serum HE4 protein upregulated diagnosis
27177284 serum miR-887-5p RNA upregulated diagnosis
27268621 serum HE-4 protein upregulated diagnosis
36510632 serum 2,3-Pyridinedicarboxylic acid metabolite upregulated diagnosis N/A
27268621 Serum HE-4 protein upregulated diagnosis
27340318 serum IL-31 protein upregulated diagnosis
27340318 serum IL-33 protein upregulated diagnosis
27549092 serum CA-125 protein upregulated prognosis unfavorable
27562869 serum HE4 protein upregulated diagnosis
27562869 serum CA125 protein upregulated diagnosis
27562869 serum CA724 protein upregulated diagnosis
27562869 serum CA19-9 protein upregulated diagnosis
28098927 serum HE4 protein upregulated diagnosis
28374920 serum DJ-1 protein upregulated diagnosis
36510632 serum Hematommic acid, ethyl ester metabolite upregulated diagnosis N/A
28383326 urine neopterin metabolite upregulated diagnosis
28401338 serum HE4 protein upregulated prognosis unfavorable
28618925 serum DJ-1 protein upregulated diagnosis high-risk endometrial cancer patients
28624692 serum YKL-40 protein upregulated prognosis unfavorable
28624692 serum CA125 protein upregulated prognosis unfavorable
28751757 plasma L1CAM protein upregulated prognosis predicts lymph node metastases
28800309 serum CA125 protein upregulated prognosis unfavorable
29092787 serum estriol (E3) metabolite upregulated prognosis unfavorable
29092787 serum estrone-sulfate (E1-S) metabolite upregulated prognosis unfavorable
29092787 serum 4-methoxy-E2 (4MeO-E2) metabolite upregulated prognosis unfavorable
36510632 serum Maltitol metabolite upregulated diagnosis N/A
29114696 serum cancer antigen 15-3 protein upregulated diagnosis identify high-risk patients
29382392 serum DNA integrity index DNA diagnosis
29463191 serum HE4 protein upregulated prognosis recurrent
29516012 serum visfatin protein upregulated prognosis unfavorable
29626374 cytology CC3 protein downgulated prognosis unfavorable
29848072 serum miR-29b RNA downgulated prognosis unfavorable
29848072 serum miR-29b RNA upregulated diagnosis
29898448 serum ProGRP protein upregulated diagnosis
29936727 serum neutrophil lymphocyte ratio (NLR) cell upregulated diagnosis
29984790 serum MACC1 protein diagnosis
36510632 serum 13(S)-HODE metabolite upregulated diagnosis N/A
29984790 serum c-Myc protein diagnosis
30314462 plasma API protein upregulated treatment
30414437 serum HE4 protein diagnosis
30508211 serum CA125 protein upregulated diagnosis predict lymph node metastasis （in aged > 50 years ）
30577833 serum ELR cell upregulated prognosis unfavorable
30577833 serum ENLR cell upregulated prognosis unfavorable
30614088 cytology IMP3 protein upregulated diagnosis
30618036 plasma the total amount of microparticles protein upregulated diagnosis
30618036 plasma endothelial (CD144+) protein upregulated diagnosis
30618036 plasma endothelial (CD144+) protein upregulated treatment
36510632 serum D-Mannitol metabolite upregulated diagnosis N/A
30618036 plasma monocytic (CD14+) protein upregulated diagnosis
30618036 plasma monocytic (CD14+) protein upregulated treatment
30618036 plasma the total amount of microparticles protein upregulated treatment
30645608 plasma GDF-15 protein upregulated prognosis unfavorable/recurrence
32761720 serum 16α-OHE1 -ERα metabolite high-affinity antigen for EC antibodies diagnosis
33059604 urine MCM5 protein upregulated diagnosis non-invasive aid
33099933 serum CA72-4 protein upregulated diagnosis
33099933 serum CA15.3 protein upregulated diagnosis
33143739 urine GHSR DNA increased methylation levels diagnosis non-invasive detection
33143739 urine SST DNA increased methylation levels diagnosis non-invasive detection
36751747 serum miB99b RNA upregulated diagnosis
33143739 urine ZIC1 DNA increased methylation levels diagnosis non-invasive detection
33148127 serum HE4 protein prognosis unfavorable
33156532 serum HE4 protein upregulated diagnosis predicte advanced disease
33208911 plasma LGALS3BP protein upregulated diagnosis
33208911 plasma LGALS3BP protein upregulated prognosis unfavorable
33360772 serum C22-ceramides metabolite diagnosis
33360772 serum C16-ceramide metabolite diagnosis
33360772 serum hydroxyhexadecenoylcarnitine metabolite diagnosis
33360772 serum 1-methyladenosine metabolite diagnosis
33360772 serum C22-ceramides metabolite upregulated diagnosis
36751747 serum miR-16 RNA upregulated diagnosis
33360772 serum C16-ceramide metabolite upregulated diagnosis
33360772 serum hydroxyhexadecenoylcarnitine metabolite upregulated diagnosis
33360772 serum 1-methyladenosine metabolite upregulated diagnosis
33436780 serum HE4 protein upregulated diagnosis
33448001 plasma NLR cell upregulated prognosis unfavorable
33448001 plasma PLB cell upregulated prognosis unfavorable
33528032 serum HE4 protein downgulated diagnosis low risk
33536036 plasma circulating tumor DNA (ctDNA) DNA ctDNA detect prognosis tumor recurrence
33660848 serum CEA protein upregulated diagnosis
33660848 serum periostin protein upregulated diagnosis
36751747 serum miR-125a RNA upregulated diagnosis
33660848 serum IDO protein upregulated diagnosis
33660848 serum CEA protein upregulated diagnosis
33660848 serum periostin protein upregulated diagnosis
33660848 serum IDO protein upregulated diagnosis
33781255 plasma Plasma-derived exosomal miR-15a-5p RNA upregulated diagnosis
33896823 plasma miR-146a-5p RNA altered expression diagnosis
33896823 plasma miR-151a-5 RNA altered expression diagnosis
33896823 plasma miR-142-3p RNA altered expression diagnosis
34076790 serum miRNA 27a RNA upregulated diagnosis
34076790 serum miRNA150-5P RNA upregulated diagnosis
34974784 serum YKL-40 protein upregulated diagnosis N/A
36751747 serum miR-145 RNA upregulated diagnosis
34099314 serum glycine metabolite treatment novel target
34099314 serum serine metabolite treatment novel target
34099314 serum SM C18:0 metabolite treatment novel target
34099314 serum free carnitine metabolite treatment novel target
34109467 serum HE4 protein upregulated prognosis unfavorable
34689374 cytology CD10 protein upregulated diagnosis
34802721 serum C-reactive protein protein upregulated prognosis unfavorable
35323926 plasma zinc finger and SCAN domain containing 12 (ZSCAN12) and/or oxytocin (OXT) DNA hypermethylation diagnosis N/A
35449078 serum circulating cell free DNA DNA upregulated diagnosis
35449078 serum citH3 protein upregulated diagnosis
36807337 urine CRNN protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
35575391 serum DJ-1 protein upregulated prognosis prediction of early recurrencies
35575391 serum HE4 protein upregulated prognosis prediction of early recurrencies
36396713 plasma CA125 protein upregulated diagnosis predictor of endometrial cancer lymphovascular space invasion and lymph node metastasis
36596280 serum CA125 protein upregulated diagnosis predict lymph node metastasis
36715558 plasma HE4 protein upregulated treatment progestin treatment response
36721236 plasma SLERT RNA upregulated treatment therapeutic target
36799979 serum ursodeoxycholic acid lipidomic upregulated diagnosis
36799979 serum PC(O-14:0_20:4) lipidomic upregulated diagnosis
36799979 serum Cer(d18:1/18:0) lipidomic upregulated diagnosis
36807337 urine SPRR1B protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine CALML3 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36918859 serum CA125 protein upregulated diagnosis deep myometrial invasion
7631667 serum colony-stimulating factor 1 protein upregulated prognosis presence and activity (progression, stabilization, or regression) of primary or recurrent disease
7737582 serum CA125 II protein diagnosis
8088605 serum CA 15-3 protein upregulated prognosis unfavorable
8088605 serum CA 125 protein upregulated prognosis unfavorable
8088608 serum CA19-9 protein upregulated prognosis recurrent
8088608 serum CA 125 protein upregulated prognosis recurrent
8137210 serum OVX1 protein upregulated diagnosis
8137210 serum OVX1 protein upregulated prognosis
8317901 serum sIL-2R protein upregulated diagnosis
36807337 urine CALML3 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
9038731 serum CA 72-4 protein prognosis predicting and monitoring recurrence,extracorporeal spread
9218009 serum CA15.3 protein upregulated prognosis unfavorable
9390137 cytology Calretinin protein upregulated diagnosis positive identification of normal and tumor mesothelial cells in serous effusions.
9473168 plasma melatonin protein upregulated diagnosis screening
9648586 serum CA125 protein upregulated diagnosis preoperative evaluation and postoperative surveillance of endometrial carcinoma
9804252 plasma PP14 protein upregulated diagnosis
9804252 cytology PP14 protein upregulated diagnosis
36807337 urine TXN protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine FABP5 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine C1RL protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine MMP9 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine ECM1 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
36807337 urine S100A7 protein combining SPRR1B, CRNN, CALML3, TXN, FABP5, C1RL, MMP9, ECM1, S100A7 and CFI diagnosis
35076938 serum 6-keto-PGF1α metabolite a biomarker panel including 6-keto-PGF1α, PA(37:4), LysoPC(20:1) and PS(36:0) diagnosis
10985893 serum CK-20 protein upregulated diagnosis metastasis
10999747 serum Serum soluble fas OTHERS upregulated prognosis unfavorable
11268474 serum CA125 protein upregulated prognosis unfavorable
11504312 serum endostatin protein upregulated treatment decreased significantly after treatment,marked elevations at clinical relapse.
11504312 serum VEGF protein upregulated treatment decreased significantly after treatment,marked elevations at clinical relapse.
11930622 serum CA125 protein upregulated prognosis unfavorable
12479072 serum VEGF protein upregulated diagnosis monitoring the progress of the disease
12820355 serum CEA protein prognosis unfavorable
12926169 serum CA 125 protein upregulated prognosis
12926169 cytology peritoneal cytology OTHERS upregulated prognosis
35076938 serum PA(37:4) metabolite a biomarker panel including 6-keto-PGF1α, PA(37:4), LysoPC(20:1) and PS(36:0) diagnosis
15225093 serum CD171 protein upregulated prognosis favorable
15867230 serum Human kallikrein 6 (hK6) DNA upregulated prognosis early disease recurrence and response to therapy.
15867230 plasma Human kallikrein 6 (hK6) DNA upregulated prognosis early disease recurrence
15867230 serum Human kallikrein 6 (hK6) DNA upregulated prognosis early disease recurrence
15867230 plasma Human kallikrein 6 (hK6) DNA upregulated treatment response to therapy.
15867230 serum Human kallikrein 6 (hK6) DNA upregulated treatment response to therapy.
15867230 plasma Human kallikrein 6 (hK6) protein upregulated prognosis early disease recurrence and response to therapy.
15867230 plasma Human kallikrein 6 (hK6) protein upregulated prognosis early disease recurrence and response to therapy.
16842844 serum RCAS1 protein upregulated treatment WST-1 assay，inhibit growth of immune cells
17023034 serum YKL-40 protein upregulated prognosis unfavorable
35076938 serum LysoPC(20:1) metabolite a biomarker panel including 6-keto-PGF1α, PA(37:4), LysoPC(20:1) and PS(36:0) diagnosis
17260229 serum CA-125 protein upregulated diagnosis lymph node metastasis (LNM)
17980190 serum serum p53 antibody (S-p53 Ab) protein upregulated diagnosis
18055714 serum CRP protein upregulated prognosis unfavorable
18422745 serum Midkine (MK) protein upregulated prognosis unfavorable
18431720 cytology PTEN protein upregulated diagnosis
18431720 cytology beta-catenin protein upregulated diagnosis aid in the stratification of EC into low grade and high grade EC
18431720 cytology p53 protein upregulated diagnosis high-grade EC in endometrial cytology
18495222 serum HE4 protein diagnosis
18682706 serum TFF3 protein upregulated diagnosis
18797802 serum SOD protein upregulated treatment therapy target
35076938 serum PS(36:0) metabolite a biomarker panel including 6-keto-PGF1α, PA(37:4), LysoPC(20:1) and PS(36:0) diagnosis
19194826 plasma osteopontin protein upregulated prognosis unfavorable
20570475 serum NLR cell upregulated diagnosis
20570475 serum NLR cell upregulated diagnosis
21176560 serum Hsa-miR-155 RNA diagnosis
21468050 serum HE4 DNA upregulated prognosis unfavorable
21468050 serum HE4 protein upregulated prognosis unfavorable
21616994 plasma GDF-15 protein upregulated prognosis unfavorable
21616994 plasma GDF-15 protein upregulated treatment monitoring treatment
21720250 serum HE4 protein upregulated diagnosis predict myometrial invasion
21806586 serum CA 125 protein upregulated prognosis unfavorable
35216190 serum Suprabasin (SBSN) isoform 2 protein downgulated prognosis N/A
21846440 serum CA 125 protein upregulated prognosis unfavorable
22037740 serum CA-125 protein upregulated diagnosis
22037740 serum CA-125 protein upregulated diagnosis
22037740 cytology CA-125 protein upregulated diagnosis
22037740 cytology CA-125 protein upregulated diagnosis
22037740 cytology CA-125 protein upregulated diagnosis
22037740 cytology CA-125 protein upregulated diagnosis
22146769 serum SPAG9 DNA upregulated diagnosis
22315051 serum GGT protein upregulated prognosis unfavourable
22378079 cytology Notch-1 protein upregulated diagnosis
35284957 serum two miRNAs (409 and 200c) and 8 CpG sites (4 CpGs at SLC22A18, 3 at HYAL2, and 1 at FUT7) DNA and RNA diagnosis N/A
22525819 serum HE4 protein upregulated prognosis unfavorable
22945838 serum YKL-40 protein upregulated diagnosis
22945838 serum YKL-40 protein upregulated prognosis unfavorable
23096757 serum HE4 protein upregulated prognosis
23179397 serum HE4 protein upregulated diagnosis
23438672 serum Visfatin protein upregulated prognosis unfavorable
23583212 serum HE4 protein upregulated prognosis predictor of metastatic disease
23583212 serum CA125 protein upregulated prognosis predictor of metastatic disease
23700142 plasma API OTHERS upregulated diagnosis
24011381 serum albumin protein pre-treatment serum albumin ≤42.1 mg/dl prognosis unfavorable
36037113 serum miR133a-2 RNA upregulated prognosis unfavorable
24211402 serum HE4 protein upregulated prognosis unfavorable
24211402 serum HE4 protein upregulated prognosis unfavorable
24316923 serum tumor-associated carbohydrate antigen sTn protein diagnosis
24420153 serum VEGF protein upregulated diagnosis predictive metastases
24460345 serum SPAG9 protein upregulated diagnosis
24614826 serum DJ-1 protein diagnosis
24614826 serum DJ-1 protein diagnosis
24659664 serum CA 125 protein prognosis unfavorable
24722971 urine 4-OHE2 metabolite upregulated diagnosis risk of estrogen-induced endometrial cancer
25202086 cytology IgA autoantibody against DLDDLD（dihydrolipoamide dehydrogenase） protein upregulated diagnosis

Institutes for Systems Genetics, West China Hospital
     Copyright @ 2023 ISG. All Rights Reserved.