Biomarker name Biomarker type Expression pattern Clinical application Application supplementary Sample type PMID
BMP protein upregulated treatment therapeutic target N/A 34360647
MMR protein protein methylation status treatment response to adjuvant therapy tissue 33449452
HAI-1 protein upregulated treatment therapeutic target tissue 20715109
HAI-2 protein upregulated treatment therapeutic target tissue 20715109
claudins protein upregulated treatment therapeutic target tissue 19795358
EphA2 protein upregulated treatment therapeutic targe in hormone receptor-negative EEC tissue 19396818
superoxide dismutase(SOD) protein upregulated treatment therapeutic target tissue 18797802
superoxide dismutase(SOD) protein upregulated treatment therapeutic target serum 18797802
aquaporin-1 (AQP1) protein upregulated treatment therapeutic target tissue 18313673
RCAS1 protein upregulated treatment predict treatment response serum 16842844
CRBP-1 protein downgulated treatment therapeutic target tissue 16575402
Twist protein upregulated treatment therapeutic target tissue 16564917
folate receptor alpha protein upregulated treatment therapeutic target tissue 33323854
p27 protein upregulated treatment predicting medroxyprogesterone acetate therapy tissue 16515645
Human kallikrein 6 (hK6) DNA upregulated treatment response to therapy plasma 15867230
Human kallikrein 6 (hK6) DNA upregulated treatment response to therapy serum 15867230
Smad7 DNA upregulated treatment potential target to restore TGF-beta responsiveness tissue 15661223
17beta-HSD type 2 protein in situ abundance treatment progestogen treatment tissue 12780745
PRB protein in situ abundance treatment progestogen treatment tissue 12780745
beta-catenin protein upregulated treatment progestogen treatment tissue 12708483
AgNORs protein upregulated treatment predict sensitivity to radiotherapy tissue 11917578
endostatin protein upregulated treatment predict treatment response serum 11504312
VEGF protein upregulated treatment predict treatment response serum 11504312
FTO DNA upregulated treatment therapeutic target tissue 33103587
AL161431.1 RNA upregulated treatment therapeutic target tissue 32196580
BANCR RNA upregulated treatment therapeutic target tissue 27898420
CCAT1 RNA upregulated treatment therapeutic target tissue 32173521
CDKN2A DNA hypermethylation treatment therapeutic targe N/A 26283007
VEGFR2 protein upregulated treatment N/A tissue 35241527
Musashi-1 protein upregulated treatment therapeutic target N/A 35619161
SLERT RNA upregulated treatment therapeutic target tissue 36721236
SLERT RNA upregulated treatment therapeutic target plasma 36721236
HE4 protein upregulated treatment progestin treatment response plasma 36715558
PDL-1 protein upregulated treatment therapeutic target tissues 35220229
FTO protein upregulated treatment therapeutic target tissue 33103587
PD-L1 protein upregulated treatment therapeutic target tissues 35804040
TIM-3 protein upregulated treatment therapeutic target tissues 35804040
B7-H3 protein upregulated treatment therapeutic target tissues 35804040
lymphocyte activation gene-3 protein upregulated treatment therapeutic target tissues 35749914
L1CAM protein upregulated treatment platinum response tissue 35429348
L1CAM DNA upregulated treatment platinum response tissue 35429348
MMRd/MSI-H protein upregulated treatment response to immune checkpoint tissue 34902958
apparent diffusion coefficient (ADC) Image DNA treatment fertility-sparing treatment Image 35469683
HER2 protein upregulated treatment targeted therapy tissue 36516643
HER2 protein upregulated treatment targeted therapy tissue 36939053
mismatch repair status DNA mismatch repair deficiency treatment predict hormone therapy response tissue 33039397
Lymphocyte activation gene (LAG)-3 protein upregulated treatment therapeutic target tissue 36509464
MHC class I status protein downgulated treatment resistance mechanism to immune checkpoint inhibition tissue 33011747
MHC class I status protein downgulated treatment selecting endometrial cancer patients for checkpoint inhibition tissue 33011747
CDK9 protein upregulated treatment therapeutic target tissue 32901849
hsa_circ_0002577 RNA upregulated treatment therapeutic target tissue 32847606
ARID1A protein downgulated treatment immune checkpoint inhibitor response tissue 32594230
GABPA protein downgulated treatment therapeutic target tissue 34306255
RRBP1 protein upregulated treatment therapeutic target tissue 30684972
SNF5 protein upregulated treatment therapies target/Knockdown of SNF5 inhibits the expression of p21 tissue 30683081
endothelial (CD144+) protein upregulated treatment plasma 30618036
monocytic (CD14+) protein upregulated treatment plasma 30618036
the total amount of microparticles protein upregulated treatment plasma 30618036
SMOC-2 protein upregulated treatment therapeutic target, enhanced resistance toward chemotherapy tissue 30594556
Autotaxin DNA upregulated treatment therapeutic target tissue 30374843
ALDH1 protein upregulated treatment therapeutic target tissue 30372483
CD44 protein upregulated treatment therapeutic target tissue 30372483
ZIC2 protein upregulated treatment therapeutic target tissue 34278490
plasma amino acid profile-based index protein upregulated treatment predict treatment response and remission plasma 30314462
PD-1 protein upregulated treatment potential target for immunotherapy tissue 30134343
PD-L1 protein upregulated treatment potential target for immunotherapy tissue 30134343
PD-L2 protein upregulated treatment potential target for immunotherapy tissue 30134343
PR protein upregulated treatment therapeutic target and predictor of treatment response tissue 29869299
AR protein upregulated treatment therapeutic target and predictor of treatment response tissue 29869299
ER-alpha protein upregulated treatment therapeutic target and predictor of treatment response tissue 29869299
ABHD11-AS1 RNA upregulated treatment therapeutic target tissue 29799152
PIR2 protein upregulated treatment targeted therapy tissue 29724995
HOMA-IR OTHERS upregulated treatment predicted poor response to progestin serum 34162378
RNF144B protein upregulated treatment therapeutic target tissue 29724995
CIP2A protein upregulated treatment therapeutic target tissue 29274810
HER2 protein upregulated treatment benefit of anti-HER2 treatments tissue 29169184
IRAK1 protein upregulated treatment therapeutic target tissue 28980703
IRAK1 DNA upregulated treatment therapeutic target tissue 28980703
SUSD2 protein downgulated treatment chemotherapeutic target N/A 28841682
EMP2 protein upregulated treatment reducing endometrial cancer stem cells tissue 28604744
EZH2 protein upregulated treatment therapeutic target tissue 28418882
miR-944 RNA upregulated treatment therapeutic targe tissue 28178620
S100P protein upregulated treatment drug target，quamous cell and adenosquamous carcinoma subtypes of endometrial cancer tissue 27918216
lncRNA NEAT1 RNA upregulated treatment therapeutic target tissue 34153644
Fzd2 protein upregulated treatment therapeutic target tissue 27373314
ERRα protein upregulated treatment therapeutic target tissue 27153547
HDACs 1 protein upregulated treatment therapeutic target tissue 27127168
HDACs 4 protein upregulated treatment therapeutic target tissue 27127168
HDACs 6 protein upregulated treatment therapeutic target tissue 27127168
HDACs 7 protein upregulated treatment therapeutic target tissue 27127168
HDACs 8 protein upregulated treatment therapeutic target tissue 27127168
survivin protein upregulated treatment therapeutic target N/A 27079211
SLUG protein upregulated treatment therapeutic target tissue 27003026
CD169 protein upregulated treatment monitoring anti-tumor immunity tissue 26991548
glycine metabolite treatment novel target serum 34099314
CXCR4 DNA upregulated treatment therapeutic targe N/A 26678890
CXCR4 protein upregulated treatment therapeutic targe N/A 26678890
CXCR7 DNA upregulated treatment therapeutic targe N/A 26678890
CXCR7 protein upregulated treatment therapeutic targe N/A 26678890
CCNE1 DNA upregulated treatment targeted therapy tissue 26647729
TOP2A protein upregulated treatment receiving adjuvant taxane-platinum regimens tissue 26588239
CDK6 protein upregulated treatment chemosensitive tissue 26554657
CDK6 protein upregulated treatment chemosensitchenm ive tissue 26554657
Sperm-associated antigen 9 (SPAG9) protein upregulated treatment progestin treatment tissue 26334303
Sperm-associated antigen 9 (SPAG9) protein upregulated treatment progestin treatment tissue 26334303
serine metabolite upregulated treatment novel target serum 34099314
phosphoglucose isomerase (PGI) protein upregulated treatment therapeutic target tissue 26308071
phosphoglucose isomerase (PGI) protein upregulated treatment therapeutic target serum 26308071
CDC20 protein upregulated treatment therapeutic target tissue 26245990
Autocrine motility factor protein upregulated treatment therapeutic target tissue 26201353
Enolase-1 protein upregulated treatment therapeutic target tissue 25951350
G9a protein upregulated treatment therapeutic target tissue 25613390
Yes-associated protein (YAP) protein upregulated treatment therapeutic target/predict radiation sensitivity tissue 24972085
CYP1A1 protein upregulated treatment chemotherapeutic targets tissue 24957043
CYP1A1 DNA upregulated treatment chemotherapeutic targets tissue 24957043
CYP1B1 protein upregulated treatment chemotherapeutic targets tissue 24957043
SM C18:0 metabolite upregulated treatment novel target serum 34099314
CYP1B1 DNA upregulated treatment chemotherapeutic targets tissue 24957043
MRE11 protein downgulated treatment sensitivity to PARP-inhibitor tissue 24927325
CGRRF1 DNA downgulated treatment metformin response tissue 24680596
stathmin protein upregulated treatment paclitaxel treatment tissue 24587245
CD117 protein upregulated treatment therapeutic targe(targeting of the SCF/CD117 axis) tissue 24333732
hPEBP4 protein upregulated treatment potential target tissue 23818363
ER-α36 protein upregulated treatment tissue 23257935
ERRγ protein ERRγ-positive/ERα-negative status treatment predictive marker for the treatment tissue 23051957
ERα protein ERRγ-positive/ERα-negative status treatment predictive marker for the treatment tissue 23051957
BST2 protein upregulated treatment therapeutic target tissue 22729361
free carnitine metabolite treatment novel target serum 34099314
emmprin protein downgulated treatment theranostic target tissue 22640183
miR-125b RNA aberrantly expressed treatment targeting ERBB2 tissue 22460089
survivin DNA allele C treatment therapeutic implications tissue 21897272
Ras-PI3K/mTOR pathway protein downgulated treatment predicting sensitivities to such agents N/A 21772091
GDF-15 protein upregulated treatment monitoring treatment plasma 21616994
epithelial cell size ratio Image higher epithelial cell size ratio after 4 weeks + lower Ki-67 nuclear antigen labeling treatment progestin therapy tissue 21551965
Ki-67 nuclear antigen labeling protein higher epithelial cell size ratio after 4 weeks + lower Ki-67 nuclear antigen labeling treatment progestin therapy tissue 21551965
Stathmin protein upregulated treatment redictive marker for response to PI3Kinase inhibition tissue 21242118
E-cadherin protein upregulated treatment theranostic target tissue 20874004
CDH1 DNA hypermethylation treatment therapeutic targe tissue 20874004

Institutes for Systems Genetics, West China Hospital
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