Study design

prospective observatiol cohort study

Study time

2017.3-2018.5

Country

China

Object

The eligibility criteria for enrollment were as follows: (1) no history of diagnosis or treatment for other maligncies; (2) no history of neoadjuvant androgen deprivation therapy for PCa; (3) no history of inflammatory conditions that might affect the immune system as assessed by a white blood cell count less than 10,000 cells/mL and C-reactive protein less than 1.0 mg/L; and (4) no history of exposure to immunosuppressive agents.

Sample size

51

Topic classification

Other

Keypoint

NK cell activity was significantly higher postoperatively than preoperatively. Patients with positive surgical margins had lower postoperative NK cell activity than those with negative margins. Lower postoperative NKA was also observed in higher-stage PCa.

Year