Study design

retrospective

Study time

2013.8-2019.5

Country

Japan

Object

Patients were included in this study if the biopsy highest GS was GS 4+3 and GS 4+4 and RALP was performed

Inclusion criteria

atients were excluded if there was no evidence of nodal or distant metastases on preoperative imaging, Gleason pattern 5 was present in any biopsy cores, neoadjuvant hormol therapy was used, prior radiation therapy was performed, the diagnostic prostate-specific antigen (PSA) level was ≥20 ng/ml, or cancer was clinical stage ≥cT3.

Sample size

122

Topic classification

Prediction，Pathology

Keypoint

Patients with biopsy GS 4+4 and 4+3 often exhibit a downgrade to GS 3+4 or less in prostatectomy specimens. The lower percentage of highest GS cores out of positive biopsy cores was associated with downgrade.

Year