Institutes for Systems Genetics, West China Hospital
Copyright @ 2023 ISG. All Rights Reserved.
| PMID | Topic classification | Keypoint |
|---|---|---|
| 32665997 | Other treatments，Prediction | A substantial proportion of patients with GS 3+4 prostate cancer were upgraded after RP. |
| 28988599 | Other treatments | Although AS may prevent over treatment and significant adverse effects after surgical intervention, stratification of patients with low risk prostate cancer is of paramount importance when choosing appropriate candidate for AS. The risk of adverse pathological results should be well informed in the pretreatment counseling. |
| 28153509 | Hospital | Increasing hospital robot-assisted radical prostatectomy volume was associated with improved perioperative outcomes up to approximately 100 surgeries per year, beyond which there appeared to be marginal improvement. |
| 34138904 | Hospital | High surgeon and hospital volume were associated with better outcomes. |
| 23069384 | Hospital | Hospitals with the greatest volume increases are specialty centers already performing a high volume of radical prostatectomy procedures. |
| 33513885 | Hospital | Hospital volume significantly affected PSM and biochemical-failure-free survival in robotic RP, but not in nonrobotic RP. When patients with PC want to receive robotic RP, it should be performed in a relatively high-volume hospital (>100 patients/year). |
| 32807046 | Assistants | As far as outcomes are concerned, there were no statistically significant differences between the three bedside assistants in terms of operative time, estimated blood loss, length of stay, days of catheterization, positive surgical margin rate. |
| 31808399 | Assistants | Previous bedside assistant experience led to an increase in self-confidence and the ability to manage troubleshooting and made it more likely for surgeons to start with more difficult cases with more challenging patients. |
| 19195692 | Focus on RARP，Sexual function | A scoring system for the extent of circumferential FP during prostatectomy is a stronger predictor of postoperative erectile function recovery than is laterality (bilateral or unilateral) or fascial depth (interfascial or intrafascial). More ventral FP significantly contributed to postoperative erectile function recovery. |
| 25129475 | Medication，Intraoperative operation | Both anaesthetic techniques significantly seem to increase the risk of thrombosis in prostate cancer patients undergoing laparoscopic prostatectomy, mainly when the robotic device was utilized, encouraging the use of a peri-operative thromboembolic prophylaxis in these patients. |
| 27841089 | Medication | Postoperative tadalafil treatment may be temporarily effective for the recovery of the IPSS storage symptom scores and OABSS. |
| 35063205 | Medication | ω- 3 supplements can be safely taken before radical prostatectomy without increasing surgical bleeding risk. |
| 29594551 | Other treatments | The superior preservation of pad-free continence and erections sufficient for intercourse with focal irreversible electroporation compared to RARP up to 12 months after treatment. |
| 33248139 | Medication | Perioperative continuation of anticoagulant use is feasible for patients undergoing robot-assisted radical prostatectomy. |
| 26341038 | Supplementary Examination，Prediction | The neutrophil-to-lymphocyte ratio was not useful in predicting adverse pathologic outcomes in our patients with low-risk PCa. |
| 34219063 | Supplementary Examination，Prediction | The ability of neutrophile to lymphocyte ratio calculated preoperatively is an easy diagnostic method that can predict GS upgrading in patients scheduled for radical prostatectomy for prostate cancer. |
| 33819496 | Supplementary Examination，Comparison of surgical techniques | Although postoperative serum Neutrophil Gelatinase-Associated Lipocalin levels were increased in both Retropubic Radical Prostatectomy and RALP, the 6-h NGAL levels were higher in Retropubic Radical Prostatectomy. RALP was associated with fewer intraoperative blood loss and fluid administration, and shorter length of hospital stay. |
| 32551332 | Supplementary Examination，Complications | As transfusion following minimally invasive radical prostatectomy is rare, scheduled postoperative hemoglobin assessments in the absence of symptoms are unnecessary to recognize bleeding events. The largest hemoglobin difference between men who did vs did not receive transfusion was seen at 14 hours postoperatively. |
| 28785191 | Supplementary Examination | In a contemporary cohort of patients, preoperative plasma levels of total testosterone directly and independently associated with high grade PCa. High baseline plasma levels of total testosterone might have clinical applications for managing PCa. |
| 27637685 | Learning curve | Reporting a preliminary experience of a proctor-based team approach in robot-assisted laparoscopic prostatectomy (RALP) for the treatment of localized prostate cancer. |
| 19888970 | Learning curve | RALP is a safe and reproducible procedure and offers a short learning curve for experienced laparoscopic surgeons. |
| 32192919 | Learning curve | RS-RARP can be safely performed by inexperienced surgeons who have received adequate training. |
| 29072565 | Learning curve | Even when controlling for copredictors, a statistically significant learning curve for PSM rate of a surgeon with significant previous LRP experience was not detected during the first 400 RARP cases. |
| 21226623 | Pathology | In patients with Gleason 6 prostate cancer in one or two biopsy cores, 25% have more ominous pathology at RARP. |
| 25443913 | Learning curve | A surgeon with extensive open and laparoscopic experience presents a safe learning curve in regard to robot-assisted radical prostatectomy and extended pelvic lymph node dissection. With increasing experience, the rates of overall and positioning-related complications significantly decrease after 175 procedures. No detrimental effect on renal function is to be expected. |
| 22556136 | Learning curve | RARP is safe and reproducible even during the initial learning curve. Overcoming the learning curve is multifactorial and is necessarily dependent on the surgeon. However, joining a well-trained team probably affects positively the performance of the surgeon. |
| 19245295 | Learning curve | RALP perioperative parameters improved throughout the first 100 cases, while postoperative outcomes remained acceptable. Methods to improve patient safety and outcome occurred throughout the series. Even during the initial learning curve for this procedure, RALP appears to be another alternative for achieving prostate cancer control. |
| 24917775 | Learning curve | Robotic radical prostatectomy is a safe procedure with low morbidity. As surgeons progress through the learning curve peri-operative parameters and oncological outcomes improve. This learning curve is not affected by the introduction of a fellowship-training programme. |
| 25927060 | Learning curve | Previous large-volume experience of laparoscopic radical prostatectomy may shorten the learning curve for RARP in terms of oncological outcome. Additionally, previous experience with laparoscopy may improve the functional outcomes of RARP. |
| 30521164 | Learning curve | Although the bedside assistant's experience in RARP does not appear to influence the robotic surgeon's oncological outcomes during the learning curve, it may reduce the potential complications by shortening the total operation time. |
| 31306669 | Intraoperative operation，Sexual function | Electrostimulation of the prostate pedicle and medial side of the prostate pedicle increases the cavernosal pressure similar to the typical neurovascular bundle stimulation |
| 29279663 | Intraoperative operation，Sexual function | Hydrodissection of the NVB appears to improve erectile function after RALP. |
| 32944518 | New technique，Intraoperative operation | Low intensity extracorporeal shock wave therapy could be used as a treatment option in penile rehabilitation. |
| 32449896 | New technique，Intraoperative operation | A peritoneal flap after RARP was not found to influence the rate of postoperative lymphocele, whether asymptomatic or requiring treatment. |
| 31833722 | Other prognosis，Prediction，Comparison of surgical techniques | ORP, ePLND and seminal vesicle invasion are independent predictors of the risk of hospital readmission over the long term at a large single tertiary referral center. |
| 30979636 | New technique | With the introduction of the elastic 3D virtual models, prostate deformation is correctly simulated during surgery and lesion location is correctly identified, even in dynamic reality with a subsequent potential reduction of positive surgical margin rate and, in the meantime, maximization of functional outcomes. |
| 32883625 | New technique | Augmented reality-3D guided surgery is useful for improving the real-time identification of the index lesion and allows changing of the NS approach in approximately one out of three cases, with overall appropriateness of 94.4%. |
| 33965288 | New technique | Digital frozen sections with Fluorescence confocal microscopy during RARP may represent an alternative to NeuroSAFE for possible optimization of functional outcomes without compromising oncological safety. |
| 35223660 | QoL | Vintage neoadjuvant hormonal therapy prior to RARP should not be recommended due to not only oncological outcomes, but also the impacts on postoperative hormonal- and sexual-related QOL. |
| 34104636 | Other | Neoadjuvant androgen deprivation therapy provides significantly better perioperative outcomes, especially in non-low risk prostate cancer, and has comparable pathological outcomes. |
| 32081564 | Other | NK cell activity was significantly higher postoperatively than preoperatively. Patients with positive surgical margins had lower postoperative NK cell activity than those with negative margins. Lower postoperative NKA was also observed in higher-stage PCa. |
| 21165525 | Other | The registry is expected to be fully compliant with the CoC standard with the recruitment of more full time cancer registrars when a new web-based cancer registry is in full operation. |
| 25484950 | Intraoperative operation，Sexual function | Recovery of erectile function in the author’s dVP series favors an athermal technique. |
| 33495942 | Medication | A structured opioid-free pain regimen following RARP is non-inferior compared to traditional opioid-based standard of care. |
| 32945234 | Medication | The use of TAP block during a RALP is a safe procedure that can be applied more appropriately to achieve better pain control. |
| 27989916 | Other prognosis | Transperitoneal RARP is a safe and efficient treatment for clinically localised prostate cancer even in patients with previous abdominal surgery. |
| 22967208 | Medication | Intravesical administration of ropivacaine may be used safely in the context of RARP and is associated with a significant, albeit modest reduction in the need for supplementary analgesic agents, but did not result in a decrease in postoperative pain scores. |
| 35474865 | Complications | Frailty was significantly associated with moderate to severe pain after RARP, and might be a potential predictor of postoperative pain. |
| 32362599 | Intraoperative operation，Prediction | Intraoperative frozen sections of periurethral tissue can independently predict PSM, whereas sections of the bladder neck and dorsal vein could not. |
| 33474847 | Intraoperative operation，Sexual function | Patients with sarcopenia can have worse erectile functional outcomes after NS RARP. Sarcopenia and a lower preoperative IIEF-5 score may be predictive of postoperative ED. |
| 33275823 | Intraoperative operation，Sexual function | There was a large discrepancy between the percentages of patients taking part in sexual intercourse and sexual activity; therefore, surveys of postoperative SF are recommended to include not only sexual intercourse but also sexual activity. |
| 32761408 | Intraoperative operation，New technique | This study demonstrates the feasibility of beta-radioguided surgery in a robotic context by means of a DROP-INβ detector. |
| 28872774 | Intraoperative operation，postoperative treatment | Incidence of adverse events in the no drain placement group was not inferior to the group who received a pelvic drain. In properly selected patients, pelvic drain placement after RARP can be safely withheld without significant additional morbidity. |
| 24440236 | Intraoperative operation，postoperative treatment | Patients randomized to suprapubic tube vs urethral catheter drainage for the week after prostatectomy had similar pain, catheter related bother and treatment related satisfaction in the perioperative period. |
| 35173071 | Intraoperative operation，MRI | In this study, the effect caused by differingpelvimetric diameters, surgical positions, andduration of anesthesia during p-RARP on anesthesiaparameters were shown. |
| 20818988 | Intraoperative operation， | A novel technique of self-cinching anastomosis using a barbed and looped suture during robot-assisted radical prostatectomy is feasible and improves posterior reconstruction and anastomotic times. Further follow-up will determine any benefits of this technique on anastomotic urinary leak rates, continence, and catheter removal times. |
| 34120255 | Other prognosis，QoL | Functional outcomes were all significantly associated with the HRQoL |
| 34168526 | Intraoperative operation， | The data indicated that lower pressure RP reduced intra-/postoperative cytokine levels. |
| 26768422 | Intraoperative operation | Directly linking 3D preoperative nuclear imaging information on sentinel lymph nodes to a robot-integrated fluorescence laparoscope improved the surgeon's use of the technology and did not influence the sensitivity or morbidity of the procedure. To our surprise, however, the detection rates with the current fluorescence camera did not improve. |
| 27751731 | Intraoperative operation | Incorporation of a urinary bladder extracellular matrix scaffold into the base of the VUA and distal bladder neck should be considered as an option to decrease morbidity associated with sRARP since it decreased the rate of VUA disruption, enhanced healing, and reduced catheterization time. This technique could be a valuable tool for all surgeons performing sRARP. |
| 33426579 | Intraoperative operation | The LigaSure system was associated with fewer positive surgical margins and shorter operation time, indicating that it could be a useful alternative to Hem-o-lok clips for controlling the prostatic pedicle in robot-assisted radical prostatectomy, despite its high costs. |
| 18564130 | Intraoperative operation | Peroperative transrectal ultrasonography during RALP decreased the positive surgical margin rate at the base of the prostate during the initial experience of RALP. |
| 30054696 | Intraoperative operation | Overall the DROP-IN design proves to be a valuable tool for robot-assisted radioguided surgery approaches. |
| 28710845 | Intraoperative operation | ChiMe applied on the NVBs after NS-RARP was feasible and safe, without compromising the duration, difficulty or complication rate of the 'standard' procedure. |
| 31187653 | Intraoperative operation | Autologous fibrin glue application reduced postoperative lymphatic drainage, and also lymphocele formation rate after extended PLND in RARP operation. |
| 30740014 | Intraoperative operation | The use of a valveless trocar system during robot-assisted robotic prostatectomy may shorten operative times, and reduce postoperative pain scores and nausea episodes without increasing the 30-day complication rate. |
| 34332759 | Intraoperative operation | The novel technique of augmented reality three-dimensional guidance for intraoperative frozen section analysis may allow for reducing PSMs at the level of the index lesion. |
| 31718600 | Other prognosis，QoL | RsRARP in high-risk PCa is feasible and results in excellent continence rates, even after postoperative radiotherapy. The potency rates are promising but need further clarification in larger cohorts. |
| 33585117 | Intraoperative operation | Lithotomy position is the standard for RALP procedures; nonetheless, it poses significant risks that might be avoided with supine positioning. |
| 33380323 | Intraoperative operation | Applying a 45° Trendelenburg position causes no difference in postoperative brain function, and does not alter cerebral oxygenation during a surgical procedure lasting up to 5 h. |
| 32174775 | Intraoperative operation | Both total intravenous anesthesia with propofol/remifentanil and volatile anesthetics with sevoflurane or desflurane/remifentanil have comparable effects on oncologic outcomes in patients undergoing RALP. |
| 32164666 | Intraoperative operation | Console time of < 4 h is important to prevent extreme elevation of intraocular pressure during RARP. |
| 29953025 | Intraoperative operation，Medication，Complications | Intraoperative mannitol administration has no beneficial effect on the prevention of acute kidney injury after RALP in prostate cancer patients. |
| 29925316 | Intraoperative operation，Medication， | The optic nerve sheath diameter was significantly lower during propofol anesthesia than during sevoflurane anesthesia 60 min after pneumoperitoneum and the Trendelenburg position. |
| 29415565 | Intraoperative operation，Medication | Mannitol decreases the optic nerve sheath diameter in patients undergoing RALP with CO2 pneumoperitoneum and the steep Trendelenburg position. |
| 28859491 | Intraoperative operation，Sexual function | Accessory pudendal arteries transection had no measurable effect on recovery of erections or potency regardless of age, preoperative erectile dysfunction, or number of accessory pudendal arteries transected. |
| 29593197 | Intraoperative operation，New technique | Although the blood pressure measured with the ClearSight system correlated with that measured invasively, a large difference between the values obtained by the two devices was noted. |
| 29124889 | Intraoperative operation，Pathology | Adoption of NeuroSAFE allowed us to offer NS in higher risk patients, whilst reducing PSM rates and at the same time improving potency at 12 months. |
| 32639601 | Other prognosis，Economy | The implementation of enhanced recovery after surgery and PreHab programs significantly changes the postoperative course of patients and may synergistically optimize RARP outcomes. The combination of these pathways improves patient recovery and is associated with reduced lengths of stay, blood loss, operative times, and costs without an increase in the postdischarge readmission rate. |
| 23415965 | Intraoperative operation，Pathology | The surface frozen section technique is associated with a low false-negative surgical margin rate. |
| 24089234 | Intraoperative operation，Pathology | Preoperative measured prostate volume in TRUS may be an indicator of intraoperative frozen section. |
| 34789219 | Intraoperative operation，Complications | Red blood cells transfusion had no significant influence on the 5-year biochemical recurrence in patients undergoing robot-assisted laparoscopic radical prostatectomy. |
| 31506877 | Intraoperative operation | No evidence of lung protective effects of lung protective ventilation compared to conventional ventilation estimated by pulmonary function tests, IL-6 levels and postoperative complications in patients undergoing RARP. |
| 31014320 | Intraoperative operation | Application of hyaluronic acid-carboxymethyl cellulose membrane to the prostate bed and neurovascular plate resulted in significantly faster postoperative return of continence after both unilateral and bilateral nerve-sparing RARP. |
| 30868938 | Intraoperative operation | During RARP, warm and humidified CO2 insufflation with the HumiGard device was more effective than the standard CO2 insufflation in maintaining the patient's heat homeostasis, even if the difference was minimal. |
| 30653808 | Intraoperative operation | Robot-assisted laparoscopic prostatectomy at a pneumoperitoneum pressure of 6 mmHg was uniformly feasible without increasing complications. Ultra-low pneumoperitoneum may confer a pain benefit, which may contribute to safe same-day discharge. |
| 30652509 | Intraoperative operation | Robot-assisted transversus abdominis plane is associated with lower postoperative pain scores and less narcotic use than local anesthetic port-site infiltration. |
| 29188199 | Intraoperative operation | RARP in the 25-degree Trendelenburg position may reduce the risks of position-related ophthalmic complications without increasing the difficulty of the surgical procedure. |
| 27225958 | Intraoperative operation | In radical retropubic prostatectomy, high positive end-expiratory pressure was associated with higher estimated blood loss, and the benefits of positive end-expiratory pressure should be weighed against the risk of increased estimated blood loss. In robot-assisted laparoscopic prostatectomy, high positive end-expiratory pressure was associated with lower estimated blood loss, and might have more than just pulmonary benefits. |
| 30649377 | Other prognosis，Pathology | The presence of TGG5 in RARP specimens had no strong impact on pathological and prognostic outcomes. |
| 26531205 | Intraoperative operation | The supine position of the patient may prevent neurological complications of the lower limbs. |
| 24428586 | Intraoperative operation | The steep Trendelenberg position used in RARP was not shown to be associated with patient positioning-related complications. |
| 35929873 | Intraoperative operation | Ultra-low-pressure RARP is a practical and safe option, and it supports the routine practice of ultra-low-pressure RARP with slow adaptation in other complex robotic surgeries, such as robotic cystectomy for bladder cancer. |
| 33816697 | Other | Preoperative information about the surgical procedure was found to be an effective factor in reducing anxiety. |
| 28798829 | Other | In the present study evaluating surgical wait time for RARP in a Canadian socialized system, increased delay for surgery does not appear to impact the pathological outcome. |
| 28230003 | postoperative treatment，Special populations | The heterogeneity of oncologic outcomes in patients with pT3 prostate cancer |
| 31719716 | postoperative treatment，QoL，Urinary Incontinence | The self-reported benefits of physiotherapy for stress urinary incontinence symptoms did not differ significantly between the two types of prostatectomy surgery at 2 years post-surgery. |
| 30248343 | postoperative treatment，Salvage | Salvage radical prostatectomy after vascular targeted photodynamic therapy treatment was feasible and safe without difficulty for most of the surgeons. |
| 18047953 | postoperative treatment | Foley catheter removal on postoperative days 8-10 after robot-assisted radical prostatectomy without routine cystography appears safe. |
| 34423666 | postoperative treatment | Enhanced recovery after surgery effectively accelerated patient rehabilitation and reduced the length of hospital stay for patients undergoing RALP. |
| 30396982 | Other prognosis，Pathology | Latent Gleason pattern5 is an important prognostic factor that should be evaluated in patients with low- and intermediate-risk for prostate cancer before the initiation of treatment. |
| 33483790 | postoperative treatment | This study demonstrates that home-based resistance exercise training is an effective and safe mode of exercise that elicits beneficial effects on aerobic exercise capacity, muscular strength and HR-QoL in men who have undergone RARP. |
| 34410984 | postoperative treatment | Pelvic drain placement is not necessary after RARP. |
| 22177263 | postoperative treatment | Percutaneous suprapubic tube placement after RARP is safe and efficacious on long-term follow-up. • Splinting of the urethrovesical anastomosis is not a critical step of RP if a watertight anastomosis and excellent mucosal apposition are achieved. |
| 33879394 | Complications | Implementation of changes in the urethrovesical anastomosis technique arising from increased awareness of surgical outcomes reduced the risk of anastomotic leaks. |
| 29264170 | postoperative treatment，Comparison of surgical techniques | PCa surgery immediately (POD 0) triggers the stress system which respond by overproduction of cortisol which induces the negative feedback mechanism that starts on POD 1, is still ongoing on POD 5, but is completely settled on POD 45. Moreover, after surgical trauma, study gives evidence that the RARP procedure associates with stress recovery faster than RRP. |
| 25216924 | Other prognosis，Local Experience | RARP is a safe procedure, has low PSM rates, high continence, and potency rates for the treatment of localized PC at experienced centers. |
| 27628466 | Other prognosis，Local Experience | RALRP is a safe and feasible technique in the treatment of localized prostate cancer. |
| 33185707 | Other prognosis，Local Experience | This longitudinal analysis of trifecta outcomes may be beneficial and should be used when counseling patients with clinically localized PCa. |
| 26881411 | Other prognosis，Local Experience | The main advantages of minimally invasive prostatectomy, i.e. low blood loss and short hospitalization, are easily achieved, while continuous effort is necessary for improvements in surgical outcomes. |
| 27388671 | Other prognosis，Local Experience | Robot-assisted radical prostatectomy is confirmed to be an oncologically safe procedure that is able to provide effective 5-year cancer control, even in patients with high-risk disease. |
| 32158334 | Other treatments，QoL | Health related quality of life was inferior at 1 month after RARP, however, recovered at 3 months after RARP and was better than after radiotherapy at 6, 12, and 24 months. |
| 31980875 | Other prognosis | Over the long term after RARP for PCA, the risk of hospital readmission is associated with ePLND. |
| 32378083 | Other prognosis，Local Experience | Men with prostatic adenocarcinoma treated with RARP in Kuwait show a high incidence of pT3 disease. |
| 27124625 | Other prognosis，Local Experience | This study suggests that the patient profile for RALP in the unit is changing, with increasing proportions of higher stage and more advanced disease being referred and operated on. However, surgical margin outcomes have remained good. |
| 30681267 | Other prognosis，Local Experience | RP for high-risk prostate cancer in the UK appears safe, regardless of modality used or surgeon volume. No clear evidence that surgeon volume impacts on early perioperative outcomes was seen. |
| 29371819 | Other prognosis，Local Experience | In Japanese patients, erection after a RARP is improved with multiNS grade procedures. |
| 32167708 | Focus on RARP，Anatomic structure | In robot-assisted perineal radical prostatectomy technique, peroperative findings and oncological outcomes can vary depending on several variable factors, but although usually not taken into account, pelvimetric measurements can also affect these outcomes. |
| 30003407 | Focus on RARP | outpatient RARP as a safe and feasible alternative to inpatient RARP for appropriately selected prostate cancer patients. |
| 26502293 | Focus on RARP | Herein we demonstrate an institutional mentoring program that effectively balances surgeon robot-assisted radical prostatectomy training and surgical quality control. |
| 28054309 | Local Experience | The number of RARP has significantly increased over the past decade and there is a trend towards surgeries on more advanced tumors with higher yields of lymph nodes dissected. At the same time, the rate of nerve-sparing procedures has significantly increased. |
| 24454607 | Comparison of surgical techniques；QoL | The results of our study found no significant difference in health-related quality of life outcomes based on surgical procedure at 12 months. Moreover, patients in both groups reported low levels of decision regret at 12 months. |
| 34538508 | Comparison of surgical techniques，Other prognosis | In this prospective multicentre controlled trial, Prostate cancer-specific mortality at 8 yr after surgery was lower for RALP in comparison to RRP. |
| 30904357 | Other prognosis | Robotic surgery after focal therapy for prostate cancer is safe and achieves postoperative continence results similar to those for robotic radical prostatectomy in treatment-naïve patients. |
| 27720782 | Comparison of surgical techniques，Other prognosis | Robot-assisted radical prostatectomy has comparable intermediate cancer control as evidenced by less use of additional postoperative cancer therapies and equivalent cancer specific and overall survival. |
| 31576266 | Comparison of surgical techniques，Learning curve，Other prognosis | For surgeons experienced in retropubic radical prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP) surgeries, RALRP is a safe and feasible surgical procedure for both oncological and functional outcomes even during the learning curve. |
| 27628630 | Comparison of surgical techniques，Learning curve | They report similar outcomes in patients undergoing RARP by a surgeon transitioning from RRP to RARP, confirming that the learning curve does not affect patient outcomes over a 2-year follow-up. |
| 18480623 | Comparison of surgical techniques，Learning curve | RALP is a feasible and reproducible technique, with a short learning curve and low perioperative complication rate. Even during the initial phase of the learning curve, good results were obtained with regard to postoperative complications and oncological outcome. |
| 32738549 | Comparison of surgical techniques，Learning curve | When Retropubic radical prostatectomy and RARP were begun contemporaneously by a novice, they showed similar learning curve patterns. The direct tactile feedback in RRP and the magnified field of view and detailed techniques in RARP help improve surgical skills complementarily to attain proficiency in both surgical types. |
| 17651548 | Comparison of surgical techniques，Learning curve | Robotic radical prostatectomy is an effective treatment modality for clinically localized prostate cancer. |
| 26343985 | Comparison of surgical techniques，Sexual function，QoL，Urinary Incontinence | This population based study reveals that men undergoing robotic assisted radical prostatectomy likely experience less decline in early urinary continence and sexual function than those undergoing open radical prostatectomy. |
| 30697080 | Comparison of surgical techniques，QoL | ORP, LRP, and RARP have similar early HRQOL outcomes with respect to urinary incontinence and erectile dysfunction. |
| 23465150 | Comparison of surgical techniques，QoL | Introduction of RALP did not result in improvement of functional outcome. There was no difference regarding urologic function/bother score or sexual function/bother score at 36-month follow-up in patients treated with LRP or RALP. |
| 23356390 | Comparison of surgical techniques，Special populations | At an experienced centre, minimally-invasive radical prostatectomy is comparable to open radical prostatectomy for high-risk prostate cance with respect to surgical margin status and biochemical recurrence. |
| 34004044 | Prediction，Other prognosis，QoL，Urinary Incontinence | Personalized information about the risk of incontinence after RARP makes more patients reconsidering their initial treatment preference. |
| 22949997 | Comparison of surgical techniques，Special populations | RALP is thought to be a more effective and safer procedure in obese patients compared with traditional open radical prostatectomy. In the management of obese patients with localized prostate cancer, RALP should be considered as a primary choice for treatment. |
| 22967039 | Comparison of surgical techniques，Economy | High surgical volume was associated with lower cost of RP. Even at high surgical volume, however, the cost of RALRP still exceeded that of RRP. |
| 28733299 | Comparison of surgical techniques，Economy | The use of RALP generates a factor 1.3 additional cost when compared with open prostatectomy and a factor 1.6 additional cost when compared with laparoscopic prostatectomies, on average, based on 12 months follow-up. |
| 24912809 | Comparison of surgical techniques，Economy | Positive surgical margin distributions after robot-assisted radical prostatectomy and laparoscopic radical prostatectomy are significantly different. The only disadvantage of robot-assisted radical prostatectomy is the lack of tactile feedback. |
| 24053198 | Comparison of surgical techniques，Economy | RARP operative times decreased by 68 min while RRP operative times remained stagnant. Higher surgeon volume was associated with shorter operative times, and selective referral or improved efficiency to the level of high-volume surgeons would net almost $15 million (USA dollars) in annual savings. |
| 29348490 | Comparison of surgical techniques，Local Experience | It is unlikely that the rapid adoption of RARP in the English NHS has produced substantial improvements in functional outcomes for patients. |
| 25770484 | Comparison of surgical techniques，Local Experience | In a Swedish setting, RALP for prostate cancer was modestly beneficial in preserving erectile function compared with RRP, without a statistically significant difference regarding urinary incontinence or surgical margins. |
| 25183452 | Comparison of surgical techniques，Local Experience | Even in its initial year, robot-assisted radical prostatectomy was carried out with several favorable safety aspects compared to the conventional surgeries despite its having the longest anesthesia time and the highest cost. |
| 32754332 | Comparison of surgical techniques，Complications | Clinicians should be aware of transient Acute kidney injury occurring after RARP, rather than ORP, to ensure better perioperative management in patients undergoing radical prostatectomy. |
| 34432012 | Comparison of surgical techniques，Complications | Undergoing RARP was associated with fewer acute and chronic postoperative complications than undergoing ORP or LRP. |
| 34155724 | PredictionOther prognosis | Factors associated with aggressive disease can predict the PSA persistence. |
| 20438567 | Comparison of surgical techniques，Complications | The overall incidence of bladder neck contracture was low in both RALP and open radical prostatectomy groups. |
| 23000849 | Comparison of surgical techniques，Salvage RARP | Salvage robotic assisted laparoscopic prostatectomy is safe, with many favorable outcomes compared to open salvage radical prostatectomy series. Advantages include superior visualization of the posterior prostatic plane, modest blood loss, low complication rates and short length of stay. |
| 27878050 | Comparison of surgical techniques | Adherence to NCCN and AUA PLND guidelines was lower during RARP than during ORP when PLND was recommended. The rate of non-recommended PLND was also higher during ORP than during RARP. |
| 22834963 | Comparison of surgical techniques | The initial results of the outcome of RALP are at least at par with those of LRP and with those of previously published RALP series. |
| 29789672 | Comparison of surgical techniques | Fast-track surgery is feasible and safe for Chinese Pca patients undergoing RALP and that it accelerates recovery, attenuates surgical stress response, and reduces morbidity compared to CS. |
| 17382723 | Comparison of surgical techniques | They failed to find evidence of an early adopter bias for patients undergoing robot assisted laparoscopic prostatectomy. |
| 34729223 | Comparison of surgical techniques | Next to an extended lymph node yield, high-grade disease was associated with a higher risk to develop symptomatic lymphocele irrespective of the technical approach. |
| 32564173 | Comparison of surgical techniques | Compared with open radical prostatectomy in the supine position, robot-assisted surgery in the extreme Trendelenburg position with capnoperitoneum did not lead to an impairment of cerebral autoregulation during the perioperative period in our study population. |
| 34970314 | Comparison of surgical techniques | For the surgical management of intermediate- and high-risk localized PCa, RARP tended to a lower risk of ≤ Grade II complications and superior functional preservation without cancer control being compromised than LRP. |
| 34631541 | Comparison of surgical techniques | For surgically managing localized PCa with a large prostate (≥50 ml), RARP had a tendency toward a lower risk of postoperative complications and better functional preservation without cancer control being compromised when compared to LRP. |
| 33951669 | PredictionOther prognosis | To avoid Symptomatic lymphoceles, RARP should be the procedure of choice. |
| 34337458 | Comparison of surgical techniques | No significant difference was observed for cancer recurrence rate between RALP and RRP 6 yr after surgery. However, in a subgroup analysis, they found a significant benefit for RALP regarding recurrence rate in the high-risk group |
| 34336234 | Comparison of surgical techniques | Comparing LRP-NS with RARP-NS in a high-volume single center, the expectation/satisfaction ratio is in favor of LRP. Worse oncologic preoperative characteristics in the RARP group may influence the higher incidence of SM+. |
| 33437271 | Comparison of surgical techniques | RARP may provide better perioperative outcomes and lower complication rates after the surgeon factor is eliminated in the early period. |
| 33240927 | Comparison of surgical techniques | Patients with larger prostates and obese patients undergoing ORP are at risk of higher blood loss, operation time or non-nervesparing procedure. Conversely, in patients undergoing RARP only obesity is associated with increased operation time. Patients with larger prostates or increased BMI might benefit most from RARP compared to ORP. |
| 33029430 | Comparison of surgical techniques | Minimally invasive surgery techniques appear to be safe, especially RALRP, which has significantly better perioperative outcomes in all subgroups of patient risk classification, and in the high-risk patient group it seems to have better pathological outcomes when compared to LRP. |
| 32748620 | Comparison of surgical techniques | RS-RARP had better perioperative outcomes and faster recovery of urinary continence compared with ORP. Short-term oncological outcomes were comparable between both surgical approaches. |
| 32648416 | Comparison of surgical techniques | The RARP approach has lower incidence rates of perioperative complications than the ORP approach, and there is a potential decreasing tendency of complication incidence rates for the RARP. |
| 32257973 | Comparison of surgical techniques | The rate of BCR-free survival was significantly higher in men classified as D'Amico high-risk patients who received RARP versus that reported in D'Amico high-risk patients who received LRP. |
| 31807424 | Comparison of surgical techniques | Minimally invasive RP techniques, such as LRPs and RALRPs, appear to be safe, have significantly better perioperative outcomes than ORPs, and have comparable pathological outcomes to those of ORPs. |
| 31603415 | Comparison of surgical techniques | Robotic prostatectomy has a shorter operative time, length of hospitalization, catheterization time, and lower early and late complication rates. |
| 30279989 | PredictionOther prognosis | The present study identified several clinical factors affecting perioperative outcomes in RARP. |
| 30937294 | Comparison of surgical techniques | Surgical and functional outcomes are better with robot-assisted surgery than with laparoscopic or open surgery in terms of estimated blood loss and urinary continence; however, no differences were found among groups in terms of biochemical recurrence and the rate of complications. |
| 29931077 | Comparison of surgical techniques | Robot-assisted laparoscopic prostatectomy and open radical retropubic prostatectomy yielded similar functional outcomes at 24 months. |
| 29757580 | Comparison of surgical techniques | We should be more careful when we perform RALP in patients at risk of impaired renal function despite being a minimally invasive surgical method with superior visual characteristics. |
| 29463975 | Comparison of surgical techniques | The advantages of RARP over RRP (complications, transfusion, conversion, hospital stay, 1-year continence) were over LRP as well, with the only exception being complications. |
| 29032582 | Comparison of surgical techniques | Men who underwent RARP had the lowest risk of developing severe urinary complications within 2 years of surgery. |
| 28662644 | Comparison of surgical techniques | RARP versus retro-pubic radical prostatectomy is associated with an improved PSM rate and BCR. |
| 28591934 | Comparison of surgical techniques | The postoperative risk profile for RARP and retro-pubic radical prostatectomy was quite similar. However, risk of anastomotic stricture was lower and risk of incisional hernia higher after RARP. |
| 26770940 | Comparison of surgical techniques | Nocturia was influenced by a range of factors, including other storage LUTS and the relief of bladder outlet obstruction after radical prostatectomy. |
| 26762928 | Comparison of surgical techniques | The 90-day postoperative mortality rates were low after RARP and RRP and there was no statistically significant difference between the methods. Given the long life expectancy among men with low- and intermediate-risk prostate cancer, very low postoperative mortality is a prerequisite for RP, which was fulfilled by both RRP and RARP. |
| 26279826 | Comparison of surgical techniques | Five-year biochemical recurrence-free survival rates of RARP are comparable to RRP in high-risk PCa. |
| 27083922 | PredictionOther prognosis | Baseline patient comorbidity, quantified by Charlson comorbidity index, was the only independent predictor of hospital LOS greater than 1 day following RARP. |
| 24733797 | Comparison of surgical techniques | RARP and ORP have comparable rates of complications and additional cancer therapies, even in the postdissemination era. Although RARP was associated with lower risk of blood transfusions and a slightly shorter length of stay, these benefits do not translate to a decrease in expenditures. |
| 24582327 | Comparison of surgical techniques | In a nationwide cohort of patients undergoing surgical treatment for prostate cancer, RALP was associated with shorter hospital stay, and lower blood loss and transfusion rates than RRP. Surgical oncologic and HRQOL outcomes were similar between groups. |
| 24255757 | Comparison of surgical techniques | RALP is associated with a lower complication rate than RRP. |
| 23485928 | Comparison of surgical techniques | Open and robot-assisted radical prostatectomy had comparable complication rates. With better patient- and tumor-related parameters as well as decreasing transfusion rates in the robot-assisted subgroup, this observation might reflect the learning curves of the involved robotic surgeons. |
| 23451984 | Comparison of surgical techniques | This study is novel in that it assesses outcomes of open RRP vs RARP in a cohort of high-risk men at a single institution. RARP appears to be a feasible option for men with high-risk prostate cancer and displayed equivalent oncological outcomes compared with open RRP. |
| 23356747 | Comparison of surgical techniques | In this relatively high risk cohort of patients undergoing radical prostatectomy we found no evidence to suggest that ORP resulted in better early oncological outcomes then RALP. |
| 23185666 | Comparison of surgical techniques | Limited PLND may help in prostate cancer staging in intermediate- and high-risk prostate cancer groups. RRP is a more effective surgical modality for PLND than is RALP, especially in high-risk prostate cancer groups. |
| 22111001 | Comparison of surgical techniques | RPP, RRP, and RALP offer similar surgical and QOL outcomes. RALP and RPP demonstrate less estimated blood loss compared to RRP.(perineal (RPP), retropubic (RRP), and robot-assisted laparoscopic (RALP) prostatectomies) |
| 21604962 | Comparison of surgical techniques | RALP was more effective and more costly. |
| 21044243 | Comparison of surgical techniques | radical retropubic prostatectomy (RRP), laparoscopic radical prostatectomy (LRP) and robot-assisted radical prostatectomy (RARP) represent effective surgical approaches for the treatment for clinically localized prostate cancer. A higher overall positive SM rate was observed for the RARP group compared to RRP and LRP; however, there was no difference with respect to biochemical recurrence-free survival between groups. |
| 34313905 | PredictionBCR | Higher GS at PSM and greater length of PSM were significant predictors of BCR after RARP. |
| 16194714 | Comparison of surgical techniques | The incorporation of robotics may result in even better surgical outcomes than conventional laparoscopy. |
| 26648678 | Comparison of surgical techniques | RARP after transurethral resection of the prostate or open prostatectomy is a challenging but oncologically promising procedure with a longer console and anastomosis time, as well as higher blood loss and higher anastomotic stricture rate. |
| 26539008 | Comparison of surgical techniques | Radical perineal prostatectomy achieved acceptable oncological control for intermediate-risk and high-risk PCa. |
| 34272595 | Comparison of surgical techniques | Surgical experience has a relevant impact on perioperative and pathological parameters RARP has a higher initial pT2-PSM rate and lower lymph node yield than open retropubic radical prostatectomy. |
| 33396327 | Comparison of surgical techniques | No significant differences in PSM or biochemical failure-free survival were observed among patients receiving open, laparoscopic, or robotic RP. |
| 24223399 | Comparison of surgical techniques | RALP has comparable oncologic outcomes compared to open radical retropubic prostatectomy, especially with higher volume surgeons. |
| 25378817 | Other | A reverse stage migration in men undergoing robotic prostatectomy. |
| 28130703 | Comparison of surgical techniques，QoL | At postoperative 3 months, Physical and Mental Components of SF-8 and Urinary Summary, all Urinary Subscales, Sexual Function and Bowel Function of EPIC showed significantly better scores in RARP group than in LRP group. RARP group showed better scores in SF-8 as well as urinary and sexual function of EPIC. |
| 28867561 | Comparison of surgical techniques，QoL | Patients who undergo robot-assisted radical prostatectomy reported lower depressive symptoms than those treated with open radical prostatectomy. Sexual desire was highly affected after radical prostatectomy with greater impairment reported by patients who underwent open radical prostatectomy. |
| 29195014 | Comparison of surgical techniques | Self-perceived penile morphometric alterations were reported in one of two patients after radical prostatectomy at long-term follow-up, with open surgery associated with a potential higher risk of this self-perception. |
| 34224165 | PredictionBCR | The construction of more reliable and potent models will provide the clinicians and patients with advantages. |
| 29427005 | Comparison of surgical techniques | The general guideline adherence regarding performing PNLD and the LN yield is high, regardless of the surgical approach. |
| 31228477 | Comparison of surgical techniques | Neither safety nor quality is diminished by R involvement in robot assisted laparoscopic prostatectomy. |
| 33559802 | Comparison of surgical techniques | Radical prostatectomy showed major postoperative complications that were independently predicted by the open approach, extended lymph-node dissection, and excessive intraoperative blood loss. |
| 28823768 | Intraoperative operation，Other prognosis | In select patients with organ confined prostate cancer partial gland ablation offered good oncologic control with fewer adverse effects that required additional treatments. Potency and continence appeared to be better preserved after partial gland ablation. |
| 28081352 | Intraoperative operation，Other prognosis | Removing the specimen with traction during robot-assisted laparoscopic radical prostatectomy does not cause a positive surgical margin. |
| 23356436 | Intraoperative operation，Other prognosis | Robot-assisted eLND achieved an increased lymph node yield and higher detection rate of lymph node metastases; however, robotic eLND did not alter biochemical outcomes in a short-term follow-up. |
| 31555579 | Intraoperative operation，Other prognosis | Robot-assisted sLND is associated with significantly reduced peri-operative morbidity compared to open sLND. No difference in LN yield, BRFS and CRFS was seen between both groups. |
| 29225060 | Intraoperative operation，Other prognosis | Among patients with clinically low-intermediate risk prostate cancer randomized to anterior (Menon) or posterior (Bocciardi) approach robot-assisted radical prostatectomy the differences in urinary continence seen at 3 months were muted at the 12-month followup. Sexual function recovery, postoperative complication and biochemical recurrence rates were comparable 1 year postoperatively. |
| 26531111 | Intraoperative operation，Prediction | Robotic malfunction was the strongest predictor of prolonged operative time. Blood loss, PSA, and gland volume were also associated with prolonged operative time |
| 35116647 | Intraoperative operation，Prediction | Cystoscopy is recommended in post-RARP patients with recurrent lower urinary tract symptoms and/or urinary retention. Prolonged length of stay after the first RARP, urine leakage, anastomotic stenosis, and positive urethra/apex margin might be predictors of Ligating clip migration. |
| 31001870 | PredictionBCR | The risk of recurrence decreases with increasing number of years without disease. An easy-to-use nomogram for conditional survival estimates can be useful for patient counseling and also to optimize postoperative follow-up strategies. |
| 28558990 | Intraoperative operation，Hospital | While PLND is not recommended for low-risk PCa by clinical practice guidelines, it was performed frequently (36.7%) in a large hospital-based data set. PLND in this population was of lower quality (nodal yield) and had less utility of detecting nodal metastatic disease than PLND in intermediate/high-risk PCa. Treatment at a high-volume or academic center was associated with increased use of PLND. |
| 28122393 | Intraoperative operation，Hospital&Surgeon | The surgeon's experience influences the occurrence of positive surgical margins, although a considerable number of surgeons carried out nerve sparing during their early robot-assisted radical prostatectomy cases |
| 32929627 | Intraoperative operation，Medication | There was no difference in adverse events, complications, symptomatic collections, or opioid use with deferral of routine drain placement after RP. |
| 25484951 | Intraoperative operation，Learning curve | Changing from open to robotic-assisted radical prostatectomy may improve the ability of urologists to obtain negative surgical margins. |
| 28488986 | Sexual function | In the setting of robotic prostatectomy, perioperative smoking cessation is associated with a significant improvement in long-term sexual functional outcome when other factors are adjusted. |
| 28677091 | Medication，Sexual function | Local use of Floseal worsens the long-term erectile function recovery in patients selected for nerve-sparing RALP. |
| 35083069 | Prediction，Sexual function | Independently to the surgical approach, operative time, more than blood loss at RP, represents a significant variable able to influence surgical margins status and post-operative erectile disfunction. |
| 22196405 | Intraoperative operation，Comparison of surgical techniques，Prediction | There is a higher rate of vesicourethral anastomotic stenosis after open RRP vs RARP. Most cases of vesicourethral anastomotic stenosis require endoscopic intervention. Predictors include open surgery, PSA recurrence, and postoperative hematuria, urinary leak, and retention. There is no diminution of quality of life scores at 12 months. |
| 29246146 | Intraoperative operation，Comparison of surgical techniques | The combined technique of RARP + BNP + posterior musculofascial reconstruction seems to be effective to determine early and long term significant effects on urinary continence of patients with comparable body mass index, age and prostate volume. |
| 19912486 | Intraoperative operation，QoL | RARP with Nerve preservation as a method of choice for treatment of prostate cancer in patients interested in preservation of erectile function and quality of life in general. |
| 23978277 | Other treatments，QoL | Patients with low-risk prostate cancer who are treated with brachytherapy or RALP report deterioration of QoL of specific domains such as voiding, continence, and sexual functioning in comparison with AS patients. A decrease of erectile function was also observed during AS. Overall QoL was similar for all three treatments options. |
| 18435807 | Prediction；Intraoperative operation | The most important risk factors for a PSM after RARP are the preoperative PSA level, PSA density, pathological stage and Gleason grade. PSM rates for a surgeon in their initial experience can be comparable to that of a surgeon experienced in RARP. Using a stapling device to control the DVC does not appear to increase the risk of a PSM, although nerve-sparing increases the rates of PSM in extraprostatic prostate cancer. |
| 33550690 | Intraoperative operation，Focus on RARP | Total extraperitoneal surgical approach is a critical factor for the success of the ambulatory with extended recovery protocol. |
| 33112984 | Intraoperative operation，QoL，Urinary Incontinence | A statistically significant improvement in early Urinary continence rate in patients who are undergoing total anatomical reconstruction and TZ sling compared to undergoing only total anatomical reconstruction. |
| 28483330 | Intraoperative operation，QoL，Urinary Incontinence | Men with low-intermediate-risk prostate cancer undergoing Retzius-sparing robot-assisted radical prostatectomy (RARP) had earlier recovery of urinary continence and lower urinary function-related bother than those undergoing standard RARP. |
| 35083072 | Intraoperative operation，QoL，Urinary Incontinence | Urethral and urinary bladder mucosal coaptation is a simple innovative technique for early continence following RARP. |
| 32158316 | Intraoperative operation，QoL，Urinary Incontinence | The combination of anterior suspension suture and long urethral stump contributed to early improvement in the continence rates. |
| 27503582 | Intraoperative operation，QoL，Urinary Incontinence | Posterior urethral suspension may improve objective measures of early urinary control compared with controls. |
| 20626271 | Intraoperative operation，QoL，Urinary Incontinence | A modified PR combines the benefits of early recovery of continence reported with the original PR technique with a reinforced watertight closure of the posterior anastomotic wall. |
| 19171418 | Intraoperative operation，QoL，Urinary Incontinence | Fascia preservation at the lateral aspect of the prostate was the best predictor of urine continence after RALP. These data suggest that preservation of fascial support lateral rather than dorsolateral to the urethra and prostate may protect neurovascular structures important to improving postprostatectomy urine continence. |
| 33623874 | Intraoperative operation，QoL，Urinary Incontinence | The combination of anterior urethral fixation and bladder neck sparing significantly increases early continence rates and decreases post-mictional symptoms after RALP without hampering oncologic outcomes. |
| 28655528 | Intraoperative operation，QoL，Urinary Incontinence | Creating an extremely small bladder neck during robot-assisted laparoscopic radical prostatectomy increases the risk of positive margins at the bladder neck without facilitating early recovery of continence. |
| 24044093 | Prediction，Other prognosis，Comparison of surgical techniques | RALP is an independent factor for the recovery of continence and that RALP has advantages for postoperative continence recovery and the quality of continence compared with RRP. |
| 27777500 | Intraoperative operation，QoL，Urinary Incontinence | Anatomic restoration improves continence rates in the early period after Robot-assisted laparoscopic radical prostatectomy. |
| 34401332 | Intraoperative operation，QoL，Urinary Incontinence | Use of puboprostatic ligament-sparing RARP could be a method to accelerate early continence without affecting the final oncological outcome. |
| 33569279 | Intraoperative operation，QoL，Urinary Incontinence | Sustainable functional urethral reconstruction is a safe and easy-to-handle modification that may contribute to early continence return for RARP. |
| 33057938 | Intraoperative operation，QoL，Urinary Incontinence | Suspension stitch improved early urinary continence following robotic prostatectomy. |
| 32674608 | Intraoperative operation，QoL，Urinary Incontinence | The Subsphincteric anastomosis significantly improved the rates of immediate, early, and 1-year continence recovery after RALP. |
| 31386793 | Intraoperative operation，Focus on RARP | Extraperitoneal SP-RARP is a feasible and safe surgical option to treat localised prostate cancer. |
| 27544575 | Intraoperative operation，Complications | This trial failed to identify a difference in lymphocele occurrence between clipping and coagulation of the lymphatic vessels at the level of the femoral canal during robot-assisted ePLND for prostate cancer. |
| 25038184 | Intraoperative operation，Complications | LN yield and the node positive rate achieved using this robotic technique are comparable to those of open series. In addition, the extent of dissection is more important than the absolute number of LNs removed in eLND, and the robotic technique is not a prohibitive factor for performing eLND. |
| 24964296 | Intraoperative operation，Complications | Minimally-invasive extended pelvic lymph node dissection before curative radiotherapy is associated with low morbidity. Asymptomatic lymphocele development rate is higher compared with open pelvic lymph node dissection. |
| 24411705 | Intraoperative operation，Complications | In the post-dissemination era, RARP remains associated with a decreased use of PLND and suboptimum extent. Efforts should be made to improve guideline adherence in performing a PLND whenever indicated according to tumor aggressiveness, despite surgical approach. |
| 32871139 | Prediction，Supplementary Examination | Combination of both biopsy improved detection rate of clinically significant PCa. |
| 27600589 | Intraoperative operation，Salvage | Robot-assisted salvage nodal dissection represents a feasible procedure in patients with nodal recurrence after RP and provides acceptable short-term oncologic outcomes, where one out of three patients experience BR immediately after surgery. Long-term data are needed to confirm the effectiveness of this approach. |
| 24166291 | Intraoperative operation，PSM | Capsular incision in normal prostatic tissue is not a predictive factor of PSM but reflected risk-taking during surgery especially when NVB preservation is indicated in low-risk prostate cancer. It can therefore only be considered a means to evaluate a surgical technique, but not a real predictor of PSM. |
| 30276864 | Intraoperative operation，BCR | Retzius-sparing robot-assisted radical prostatectomy confers effective biochemical recurrence control at the mid-term follow-up period. Preoperative prostate-specific antigen, advanced clinical stage and higher Gleason score were important predictors of biochemical recurrence after Retzius-sparing robot-assisted radical prostatectomy. |
| 28747519 | Intraoperative operation，BCR | Adding sentinel node biopsy to ePLND improves BCR-free survival, although the precise explanation of this observation remains speculative. |
| 33551295 | Intraoperative operation | Compared with the standard technique, utilization of our technique was found to be associated with an improved early recovery of urinary continence, with no increase in operating room time or perioperative complications. |
| 25422166 | Intraoperative operation | Robot-assisted radical prostatectomy appears to be a safe approach for patients with prior abdominal surgery without increasing total operative time, robotic console time, positive surgical margin or the incidence of perioperative complications. |
| 30426256 | Intraoperative operation | The Retzius-sparing approach significantly reduces time to continence following RALP. |
| 32634854 | Intraoperative operation | Lymphatic drainage patterns from the prostate can be identified and classified using indocyanine green-guided extended pelvic lymph node dissections. |
| 32327264 | Intraoperative operation | The 5-step superextended pelvic lymph node dissection approach is a reproducible and feasible technique for PCa patients at a very high risk of lymph node invasion. |
| 31899555 | Intraoperative operation | No case of positive lymph nodes in the fossa of Marcille that had skipped over other regions was confirmed. Additional lymph node dissection of fossa of Marcille did not lead to complete resection of molecularly positive lymph nodes. |
| 32737518 | Prediction，Supplementary Examination | Machine learning-based analysis of quantitative [18F]DCFPyL PET metrics can predict LNI and high-risk pathological tumor features in primary PCa patients. |
| 30398382 | Intraoperative operation | No-drain policy is equivalent to drain after RARP in terms of Clavien-Dindo score complication rate, length of hospital stay, and hospital readmission rate. |
| 29767326 | Intraoperative operation | While indocyanine gree-ePLND seems to be beneficial for a better understanding of the lymphatic drainage and a more meticulous diagnostic approach, the sensitivity is not sufficient to recommend stand-alone indocyanine gree lymph node dissection. |
| 29230586 | Intraoperative operation | ePLND, which significantly increased the console time and blood loss but nearly quadrupled the lymph node yield, is considered a relatively safe and acceptable procedure. Moreover, the results of this study suggest that ePLND improves staging and removes a greater number of metastatic nodes. |
| 28905289 | Intraoperative operation | In the largest series of node-positive patients from robotic prostatectomy and extended lymphadenectomy, those with pathologic Gleason ≥8 and positive lymph nodes ≥2 were more likely to receive additional treatment. |
| 28281741 | Intraoperative operation | extended PLND during RARP is safe and effective. It results in more removed nodes and a higher LN positivity rate compared to standard-PLND, predicting LNI without increasing complications. |
| 26742982 | Intraoperative operation | The number of lymph nodes removed was comparable to published data about open series, allowing the increase of detection rate of lymph nodal metastasis for minimally invasive approach without compromising complications' rate if performing the procedure following reported technique. |
| 25899767 | Intraoperative operation | Anterior prostatic fat pad (APFP) dissection must be done regardless of the radical prostatectomy technique chosen. In our opinion, it is not necessary to do pathological examination of the APFP tissue routinely except for the patients with high preoperative PSA values, patients with high prostate biopsy Gleason scores and patients at high risk in order to save time and cost. |
| 23521086 | Intraoperative operation | Lymphocele might preferentially develop in cases with seminal vesicle invasion and large tumor volume. Additionally, extracapsular extension, seminal vesicle invasion, and the number of positive lymph nodes are independent risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy. |
| 27628473 | Intraoperative operation | Intraoperative findings of macroscopically positive LN during RARP is a rare event that may occur in high-risk patients, particularly in those with a high PSA and biopsy perineural invasion. Long-term survival is possible after completion RARP. |
| 21851536 | Intraoperative operation | Anterior lymphofatty tissue overlying the prostate occasionally contains lymph nodes that can harbour malignant disease and routine excision may eradicate regional tumour burden. ? |
| 32789599 | Prediction，Supplementary Examination | Current Prostate-specific membrane antigen PET/CT imaging cannot replace diagnostic ePLND |
| 19515403 | Intraoperative operation | Feasibility and low complication rate of robotic standard-template PLND with lymph node yields comparable to those with open PLND. Considering the low morbidity of PLND in experienced hands, coupled with the potential of preoperative undergrading and understaging and the therapeutic benefit to patients with micrometastatic disease, an increase in overall standard-template PLND use should be considered. |
| 34692583 | Intraoperative operation | Not only the performance but also the degree and quality of NVB sparing thought to be important for postoperative sexual function |
| 34562303 | Intraoperative operation | Extended robot-assisted laparoscopic prostatectomy and extended pelvic lymph node dissection without adjuvant therapy is safe and effective for some patients with very-high-risk prostate cancer. |
| 34384621 | Intraoperative operation | Electrocautery can be applied safely, with similar outcomes to those of an athermal technique. |
| 34337544 | Intraoperative operation | A higher degree of NS significantly increased the risk of PSM but did not significantly increase the risk of cancer recurrence. Combined with the known functional benefits of NS surgery, these results underscore the need to identify an individualised balance. |
| 34222808 | Intraoperative operation | The novel technique provided very early continence at the time of catheter removal after RALP within short-term follow-up in addition to favorable oncologic results. |
| 34079768 | Intraoperative operation | transvesical Retzius-sparing robot-assisted radical prostatectomy by experienced hands was feasible for selected patients with clinically localized PCa, yielding significantly improved early return to UC and similar erectile functional preservation without compromising oncological control when compared with the standard approach. |
| 32521115 | Intraoperative operation | Suture suspension of the DVC during RARP contributes to higher overall continence rates compared to stapling and cut and suture. Nerve sparing contributes to earlier return of continence than non-nerve sparing. |
| 32402143 | Intraoperative operation | The transvesical approach is a valid alternative to RARP in selected patients, providing promising postoperative urinary continence. |
| 31964317 | Intraoperative operation | Positive surgical margins at the level of bladder neck are linked to neoplasia with adverse pathological features, rather than the "extreme" bladder neck preservation procedure. |
| 31428576 | Prediction，Medication，Special populations | Early dutasteride administration showed a significant decline in the PSA levels of patients with pathology stage >T2 and positive surgical margin. If dutasteride was provided before the PSA value increased to 0.195 ng/ml after RARP, it would reduce the probability of acquirement of RT/ADT. |
| 31586543 | Intraoperative operation | Patients with BNS had a better chance to be pad-free at 7 days after catheter removal and had a significant shorter time to catheter removal. However, this beneficial effect disappeared with time and no differences in continence rates at 3 months and 1 year were recorded. Moreover, BNS did not negatively affect positive margin or BCR rates. |
| 31579411 | Intraoperative operation | In selected high-risk PCa cases, the NS technique resulted in equivalent oncological outcomes and improved urinary continence compared with the non-NS RARP group. |
| 30041833 | Intraoperative operation | Retrograde release of the neurovascular bundle with preservation of dorsal venous complex during RARP is safe and associated with excellent oncological and functional outcomes. |
| 30021425 | Intraoperative operation | eRARP is a safe, reproducible, and effective procedure for the surgical treatment of prostate cancer. Superior functional outcome can be achieved when a bilateral intrafascial nerve-sparing approach can be performed. |
| 30006861 | Intraoperative operation | Standard and delayed approaches to DVC are safe and lead to similar functional outcomes. A delayed approach exposes to a higher risk of PSM in organ-confined disease but with a lower risk of apical involvement. |
| 29061068 | Intraoperative operation | Three-layer two-step PR using peritoneum during RARP is a simple and feasible method seeming to improve early recovery of postoperative continence compared with standard two-step PR. |
| 27743849 | Intraoperative operation | Bladder neck intussusception during robot-assisted laparoscopic prostatectomy is feasible and safe. Although the long-term effects appear limited, intussusception may improve urinary function during the early recovery period. |
| 26397733 | Intraoperative operation | A pubovesical complex reconstruction (Kim's stitch) with posterior reconstruction during RALP has a beneficial effect on continence recovery without producing additional adverse effects. |
| 24693529 | Intraoperative operation | Intraoperative blood loss was a significant risk factor for BNC. |
| 24612011 | Intraoperative operation | Retzius-sparing RALP, although technically more demanding, was as feasible and effective as conventional RALP, and also led to a shorter operating time and faster recovery of early continence. Retzius-sparing RALP was also reproducible and achievable in all cases. |
| 31964956 | Prediction，Supplementary Examination，Focus on RARP | The preoperative %p2PSA and prostate health index accurately predict adverse pathological results and are useful for decision-making. |
| 32775266 | Intraoperative operation | RALP had a significant effect on hepatic function after both TP-RALP and EP-RALP approaches, while the latter showed a lesser extent. |
| 32715451 | Intraoperative operation | The long-term outcomes of EP-RALP were analogous to those of TP-RALP. |
| 30680229 | Intraoperative operation | RARP with Nerve preservation as a method of choice for treatment of prostate cancer in patients interested in preservation of EF and quality of life in general. |
| 21992461 | Intraoperative operation | High BMI, larger prostate volume and previous TURP, but not pelvic bone size or apex shape, might hinder retro-apical transection of the urethra. |
| 22998904 | Intraoperative operation | Bladder neck sparing is associated with fewer urinary leak complications, shorter hospitalization and better post-prostatectomy continence without compromising cancer control compared to bladder neck nonsparing. |
| 22738925 | Intraoperative operation | the intrafascial dissection technique for RALRP bears a high risk of incomplete resection in localized prostate cancer resulting in unfavorable outcome. |
| 21830910 | Intraoperative operation | Although robot-assisted laparoscopic neurovascular bundle sparing radical cystoprostatectomy with bilateral intrafascial NVB preservation, bilateral extended lymph node dissection, and intracorporeal Studer pouch formation is a complex procedure, it can be performed with excellent short-term surgical and pathological outcomes and satisfactory functional results after considerable experience gained with RALRP procedures. |
| 21620561 | Intraoperative operation | Reliance on countertraction to facilitate dissecting NVB away from the prostate leads to neuropraxia and delayed recovery of sexual function and potency. Subtle technical modification to dissect the prostate away from the NVB without countertraction enables earlier return of sexual function and potency. |
| 20863611 | Intraoperative operation | DVC division followed by selective suture ligation versus DVC suture ligation followed by athermal division improves early urinary control and shortens operative times due to fewer instrument changes with late versus early DVC control. |
| 20376897 | Intraoperative operation | Rocco repair offers no significant advantage in the time to recovery of continence following RLRP when continence is defined as the use of zero pads per day. On the other hand, Rocco repair was associated with increased incidence of urinary retention requiring prolonged foley catheter placement. |
| 31136108 | Prediction，Sexual function，QoL，Urinary Incontinence | Age was a predictor of urinary and erectile function recovery in 12 months. BMI was significant factor for potency recovery |
| 20362386 | Intraoperative operation | Posterior reconstruction of the musculofascial complex does not appear to improve early urinary incontinence after RALP. |
| 19178174 | Intraoperative operation | Cold incision of the DVC before suture ligation reduces the rate of apical margin involvement during robot-assisted radical prostatectomy. |
| 18419333 | Intraoperative operation | Unilateral-sural-nerve graft functional outcomes do not appear to improve outcomes when compared with men with UL nerve preservation. |
| 33879996 | Intraoperative operation | Prolonged surgical duration is associated with biochemical recurrence in patients with positive surgical margins. |
| 29201511 | Intraoperative operation | Robot-assisted radical perineal prostatectomy is a feasible and efficient method. But still this method needs for further studies in this area. |
| 34917689 | Intraoperative operation | Inguinal hernia repair performed during the same session at RARP is a safe and applicable procedure. |
| 30891454 | Intraoperative operation | The detrusorrhaphy technique showed significantly better outcomes than those achieved with the standard RARP technique in terms of urinary incontinence. |
| 30901171 | Intraoperative operation | In RLRP, extraperitoneal robot-assisted laparoscopic radical prostatectomy was proved a safe and effective approach based on the perioperative results compared to transperitoneal robot-assisted laparoscopic radical prostatectomy. |
| 24553487 | Intraoperative operation | Modified ultradissection reduces the PSM rate for the bladder neck. |
| 30606182 | Intraoperative operation | The console time and estimated blood loss were significantly increased with a larger prostate size. extraperitoneal RARP requires meticulous bleeding control in patients with a prostate weighing > 75 g, and if appropriate management is implemented for blood loss intraoperatively, extraperitoneal RARP can be performed regardless of the prostate size. |
| 33663015 | Sexual function | The present findings suggest that robot-assisted radical prostatectomy patients who undergo not only nerve sparing, but also those who undergo patial nerve sparing could benefit from penile rehabilitation using a phosphodiesterase-5 inhibitor. |
| 22966792 | Intraoperative operation | Intrafascial robot-assisted simple prostatectomy appears to be a feasible procedure in large-volume prostatomegaly. |
| 21902975 | Intraoperative operation | Side-docking for robotic radical prostatectomy is associated with small but significant improvement in setup time and can be utilized in patients with limited hip abduction. |
| 34337474 | Intraoperative operation | RS-RARP is associated with less patient-reported penile shortening and may decrease the risk of Peyronie's disease and postoperative inguinal hernia development. |
| 34186136 | Intraoperative operation | Salvage robotic-assisted laparoscopic radical prostatectomy should be offered to patients with an early relapse after focal high-intensity focused ultrasound. The early oncological outcome is satisfactory and functional outcome one year postoperatively is similar to primary robotic-assisted laparoscopic radical prostatectomy. However, Salvage robotic-assisted laparoscopic radical prostatectomy is associated with a higher rate of Clavien-Dindo III complications (mainly, placement of a drainage), of which patients should be informed beforehand. |
| 32015914 | Intraoperative operation | The dilatation of the internal inguinal ring represents an important risk factor for IH after RARP. However, incising the peritoneum sufficiently close to the medial edge of the internal inguinal ring can prevent postoperative IH without extra products and time. |
| 33705635 | Intraoperative operation | Patients undergoing minimally invasive RP had higher adjusted rates for postprostatectomy incontinence surgery compared to open approaches, which was attributed to high rate of postprostatectomy incontinence surgery following laparoscopic approach and low rate of postprostatectomy incontinence surgery following perineal approach. |
| 22170893 | Intraoperative operation | The study supported efforts to broaden the adoption of the extraperitoneal approach for robotic prostatectomy. |
| 30978167 | Intraoperative operation | Robotic-assisted radical perineal prostatectomy has acceptable morbidity, excellent surgical and pathological outcomes, and satisfactory oncologic and functional results compared to robotic-assisted transperitoneal laparoscopic radical prostatectomy. |
| 32130477 | QoL，Comparison of surgical techniques | Marginally better general HRQOL outcomes could be detected for ORP compared to RARP 3 months postoperatively. |
| 31119473 | QoL，Intraoperative operation | No significant differences in HRQOL between anterior and posterior surgical approaches to RARP. |
| 29307683 | Sexual function，Medication | Earlier rehabilitation with phosphodiesterase type 5 inhibitors can contribute to the recovery of erectile function after radical prostatectomy in the clinical setting. |
| 32931133 | QoL，Intraoperative operation | In the initial period after RARP, bowel symptoms were significantly impaired. This impairment was affected by the degree of NS. |
| 18585849 | QoL，Comparison of surgical techniques | Patients who underwent RALP were more likely to be regretful and dissatisfied, possibly because of higher expectation of an "innovative" procedure. |
| 33359493 | QoL | Higher regret was seen in one third of patients and was associated with worse disease-specific quality of life, sexual and erectile function measures. To minimize regret, collaborative and detailed discussion should take place pre-operatively when counselling patients about RARP. |
| 31704865 | QoL | Treatment satisfaction with RARP was generally acceptable from 1 to 12 months after surgery and did not change over time. Urinary bother was associated with satisfaction at 12 months after RARP. |
| 31148505 | QoL | Urinary, bowel, and sexual activity scores return to baseline values 24 months after surgery, incontinence aid, treatment-related symptoms, and sexual functioning may remain significantly deteriorated. |
| 28425193 | QoL | Notably, sexual function recovers most for RALP patients. UI remains worse at 24 months after surgery, compared to other methods of prostate cancer treatment. |
| 30029714 | QoL | The RARP patient could benefit from a healthcare system that assesses patient sexual outcome following prostatectomy beyond potency and ability to penetrate a partner. |
| 30011984 | QoL | Most HRQOL domains showed recovery within 12 months after RP, excluding sexual functioning and social functioning. |
| 25484948 | Special populations，Sexual function，QoL，Urinary Incontinence | Younger men may have an earlier return of continence and potency when compared to men > 60 years. Despite this finding, continence outcomes appear to be equal among age groups after 1 year of follow-up. Moreover, men < 60 years continue to report superior potency outcomes compared to men > 60 years at 1 year post-operatively. |
| 28261677 | Special populations，Special populations | Gleason score 6 patients with PSA (10-20 ng/mL) have an increased risk of upgrading to pathologic GS (≥8), subsequently poorer oncological outcome thus require a stricter follow-up. |
| 32245911 | Other treatments，QoL | RALP and RT were associated with different patterns of complications and patient-reported outcomes. Urinary incontinence was much more prevalent in the patients treated surgically. |
| 30212952 | Prediction，Comparison of surgical techniques，Complications | The overall incidence of inguinal hernia after RARP was significantly associated with BMI and smoking history. |
| 25325024 | Special populations，Focus on RARP | Robot-assisted radical prostatectomy with pelvic lymph node dissection is a feasible option for very high-risk prostate cancer in elderly patients with satisfactory oncologic outcomes; however, functional outcomes were not as favorable. Patients who are unable to accept the risk of adjuvant therapy and its side effects or incontinence should be deterred from surgical treatment, and other options such as radiation therapy could be an alternative. |
| 28352618 | Special populations，Focus on RARP | RARP may be a reasonable therapeutic option for elderly patients with PCa and provides comparable perioperative and functional outcomes to those in younger patients. |
| 26166967 | Special populations，Focus on RARP | Robotic surgery is safe and feasible in a select group of elderly patients. |
| 19583731 | Special populations，Focus on RARP | The outcomes of RARP in elderly men are largely comparable to those in younger men, with the exception of higher pathological Gleason grade, a transient delay in return of continence, and taking longer to return to driving after surgery. Advanced chronological age should not be a contraindication for RARP in patients with clinically localized prostate cancer, but expectations should be managed preoperatively. |
| 32497131 | Special populations，Focus on RARP | The oncologic and surgical outcomes in the elderly group were similar to those in the younger population. However, the duration of hospitalization seemed to be longer in older patients (age ≥ 75 years), despite similar complication rates. |
| 33118115 | Special populations，QoL | Increased levels of adverse effects after RALP are significantly associated with high neuroticism. |
| 32861619 | Special populations，QoL | Frailty was not significantly associated with the worsening of HRQOL, LUTS, and pad-free continence rates in patients treated with RARP. |
| 31249271 | Special populations，Anatomic structure，Prediction，QoL，Urinary Incontinence | Unlike younger patients, only variables (age and MUL), possibly associated with the inherent function of the urinary sphincter, were predictors of recovery of UC in patients aged >70 years. |
| 32537666 | Special populations | Robot-assisted radical prostatectomy should not be denied to those over 70 years solely on the basis of age. |
| 35252339 | Special populations | Approximately every second senior patient has a misclassification in (i.e., any up or downgrade) and each 4.5th senior patient specifically has an upgrade in his final pathology that directly translates to an unfavorable PCa prognosis. |
| 35300134 | Prediction | PSA was the strongest variable to predict iPCa out of prostate with preoperative benign biopsies. |
| 32451781 | Special populations，Complications | Temporary renal dysfunction can occur after RARP due to CK elevation. Thus, sufficient attention must be paid to renal insufficiency after elevation of CK values for several days after RARP. |
| 27031340 | Special populations，BCR | Patients with single positive LN, and Gleason scores ≤7 have low risk of recurrence. |
| 28070166 | Special populations | High-risk prostate cancer patients with 1 NCCN high-risk factor can be considered for robot-assisted radical prostatectomy treatment only. |
| 25484981 | Special populations | Robotic assisted laparoscopic radical prostatectomy in experienced hands can be safely recommended to eligible patients regardless of BMI status. |
| 18246641 | Special populations | Overweight and obese men had a longer operative duration, greater blood loss, longer hospital duration, and higher positive surgical margin rate. |
| 20586661 | Focus on RARP | Guidelines for PCa need to be monitored regularly, and the compliance to guidelines has to be assessed on a regular basis. Guidelines should avoid too strict criteria, particularly in relation to age. |
| 26955501 | Other | A platform can be used for precise colocalization of novel candidate hypoxia-related proteins in a representative number of prostate cancer cases, and improve issues of single marker correlations. Furthermore, this study provides a source for further in situ tests and biochemical investigations. |
| 30777723 | Other | Retzius-sparing robot-assisted laparoscopic radical prostatectomy (RSP) is an innovative approach for localized prostate cancer treatment. |
| 32158968 | Focus on RARPOther prognosis | The report shows the safety and feasibility of SP-RARP, and that the associated surgical outcomes with short-term follow-up are satisfactory. |
| 34430418 | Focus on RARPOther prognosis | Precision prostatectomy is feasible, technically safe, and offers excellent postoperative functional results. At 36 months of follow-up, the oncological outcomes and secondary procedure rates appear to be at-par with the ablative forms of focal therapy. |
| 31922483 | Prediction，Focus on RARP | The Caprini score predicts postoperative venous thromboembolism in patients undergoing RARP. |
| 29440957 | Prediction，Sexual function | Age seems to be the most important predictor of the regain of potency after robotic radical prostatectomy. |
| 25790013 | Focus on RARP，Learning curve | Robot-assisted radical prostatectomy is a safe procedure even in the hands of surgeons with no previous experience. |
| 31464649 | Focus on RARP，QoL | Results of the confirmatory factor analysis and the measurement invariance analysis demonstrated the validity of the Italian version of the EPIC-26 to assess QoL in prostate cancer patients. |
| 33917705 | Focus on RARP，Focus on RARP | Robotic radical prostatectomy using the da Vinci Single-Site platform system is safe and feasible, with acceptable outcomes. |
| 30182076 | Focus on RARP，Local Experience，QoL | Urinary outcomes and sexual outcomes had not returned to baseline at 12 months. Recovery of sexual function was significantly greater in patients who underwent robotic surgery. Only recovery of urinary function was significantly associated with overall satisfaction 12 months after radical prostatectomy in this cohort of Korean men. |
| 34387037 | Focus on RARP，Local Experience，Special populations | Even aged over 75 years, patients who underwent RARP for non-metastatic PCa had similar survival with RT regardless of risk stratification. |
| 35005649 | Focus on RARP，Local Experience，Focus on RARP | Same-day-discharge RARP remains infrequently used in routine practice in France despite being associated with comparable short-term outcomes after RARP and potential cost benefits. |
| 23675138 | Focus on RARP，Local Experience | Both perioperative and postoperative outcomes of our series of robotic prostatectomies performed by a single surgeon at Mount Sinai Medical Center demonstrate the superb outcomes that can be achieved through this modality of treatment. |
| 27549566 | Focus on RARP，Local Experience | They found decentralization of radical prostatectomy in Germany. |
| 34692589 | Focus on RARP，Local Experience | There has been a change in profile of patients undergoing RARP and patients with more unfavorable disease characteristics such as higher prostate specific antigen and tumor grade are undergoing surgery. |
| 35083274 | Prediction，QoL，Urinary Incontinence | A lower cognitive ability should be treated as a non-modifiable risk-factor for early PPI. In the future it could find its place as a clinical screening tool to identify patients who require more attention especially in the pre-, but also in the postoperative phase. |
| 21605514 | Focus on RARP，Local Experience | The referral pattern for RALP at our institution may reflect a growing acceptance of robotic surgery among urologists in our region and is unlikely driven by patient-directed marketing. |
| 22919130 | Focus on RARP，Local Experience | Robot-assisted laparoscopic prostatectomy (RALP) is easy to learn and provides the patient with the benefits of minimally invasive surgery with minimal perioperative morbidity. |
| 25024790 | Focus on RARP，Local Experience | This study shows similar results compared to other high-volume RARP programs. |
| 22398201 | Focus on RARP，Local Experience | RARP has been incorporated at this institution with an acceptably low rate of intra-operative and postoperative complications. |
| 24171923 | Focus on RARP，Local Experience | RARP is a safe and efficient method for achieving PCa control together with functional preservation, even during the initial trial for this procedure. |
| 31620590 | Focus on RARP，Local Experience | This study demonstrated acceptable outcomes following an initial RALP procedure, despite 50% of the patients investigated demonstrating high-risk features associated with non-organ confined disease. |
| 31355454 | Focus on RARP，Local Experience | A nationwide, population-based register with transparent reporting of data on the performance of radical prostatectomy. |
| 23225803 | Focus on RARP，Local Experience | As the prostate cancer incidence increased in Korea, the proportion of localized and locally advanced cancer also increased |
| 17382147 | Focus on RARP，Local Experience | Robot-assisted radical cystectomy and pelvic lymph node dissection can be performed safely in patients who are considered candidates for open cystectomy. |
| 17893904 | Focus on RARP，Local Experience | Robotic-assisted radical prostatectomy can be performed with favorable outcomes while minimizing complications. |
| 34876905 | Prediction，QoL，Urinary Incontinence | surgical strategies encompassing the nerve-sparing technique and the Retzius-sparing procedures, namely, the transvesical or posterior approach, during RARP could independently enable early achievement of postoperative continence. |
| 21902974 | Focus on RARP，Local Experience | Robotic prostatectomy appears to be a safe and successful option for prostate cancer treatment in a teaching community hospital. |
| 26416058 | Focus on RARP，Local Experience | RARP is a minimally invasive therapeutic approach for prostate cancer, with acceptable outcomes, even in countries such as Romania, where the detection rate for localized prostate cancer is lower compared to other European countries due to lack of national screening programs. |
| 27123326 | Focus on RARP，Local Experience | Robotic surgery is validated by the oncological results at medium follow-up (2 years) for localized and locally advanced prostate cancer, even in countries where there is no on-going national screening program. |
| 27622285 | Focus on RARP，Local Experience | RALP can be performed safely in patients with prior abdominal surgery, without increasing the risk of complications. |
| 28743170 | Focus on RARP，Local Experience | During the last 6 years of RALP implementation in Belgium, there was a significant increase in the enrollment of intermediate- and high-risk PCa patients. |
| 36118377 | Focus on RARP，Local Experience | Indian patients present with more advanced disease, higher PSA and have higher incidence of extraprostatic extension. |
| 25279213 | Focus on RARP | New tools are required to predict upgrading and upstaging of our patients, in order to ensure better counseling for optimal treatment planning. |
| 29349945 | Focus on RARP | The within-group discrimination ability of preoperative the Cancer of the Prostate Risk Assessment score might help in patient counseling and selecting optimal treatments for those with intermediate-risk prostate cancer. |
| 27613061 | Focus on RARP | Robotic partial prostatectomy for isolated anterior prostate cancer is feasible with good functional results. |
| 33595217 | Focus on RARP | RALP is an oncologic effective procedure for cT3 prostate cancer. Adjuvant/salvage treatment is needed to achieve optimal disease-control. |
| 33959725 | Prediction，QoL，Urinary Incontinence | Both patient factors and surgeon kinematic metrics, recorded during robotic prostatectomies, impact early urinary continence recovery after robot-assisted radical prostatectomy. |
| 29086019 | QoL，Urinary Incontinence，Sexual function | Patients with the poorest quality of life outcomes at 90 days post-operatively were more likely to seek care via email and physical therapy encounters related to sexual function and urinary incontinence. |
| 28462944 | QoL，Urinary Incontinence，Sexual function | Patients with D'Amico high-risk PCa treated with RARP may continue to recover urinary continence and sexual function beyond 12 months of surgery and show promising outcomes at 3-year follow-up |
| 29177945 | QoL，Urinary Incontinence，postoperative treatment | In selected patients, removing the urinary catheter 48 h after RALP is feasible and safe and has no negative impact on continence if compared with the best international standards. |
| 31929596 | QoL，Urinary Incontinence，Anatomic structure | Urethral realignment using BNP and maximal urethral length preservation resulted in rapid continence recovery and good oncological results after RARP in young patients with a Gleason score ≤ 7 and organ-confined disease. |
| 24739066 | QoL，Urinary Incontinence，Anatomic structure | Maximal urethral length preservation rather than anterior bladder suspension confers higher postoperative continence rates and shorter time to achieve continence among patients with PCa who underwent RALP without increasing risk of positive margin. |
| 30548814 | QoL，Urinary Incontinence，MRI，Prediction，Anatomic structure | Pelvic parameters measured by MRI before RARP may be useful in the prediction of urinary incontinence. In particular, membranous urethral length and levator ani muscle can predict postoperative UI by strict definition. |
| 32420156 | QoL，Urinary Incontinence，MRI，Prediction，Anatomic structure | Preoperative mRUL measured on MRI was an independent predictor of immediate urinary continence following Retzius-sparing robot assisted radical prostatectomy. |
| 31384606 | QoL，Urinary Incontinence，MRI，Prediction，Anatomic structure | Preoperative membranous urethral length assessed by magnetic resonance imaging was an independent predictor of early recovery from urinary incontinence after RARP. |
| 30798475 | QoL，Urinary Incontinence | Uroflow stop test with electromyography can be considered as a noninvasive, reproducible and easily performable tool. Latency time is applicable in the clinical evaluation to predict urinary continence recovery after RARP. |
| 28718690 | QoL，Urinary Incontinence | Older age and longer operative time were highly relevant to short- and long-term post-prostatectomy urinary incontinence occurrence after RARP. |
| 32188426 | Prediction，QoL，Urinary Incontinence | Pelvic lymph node dissection, Nerve-sparing, and age were significant determinants of continence in the early and late stages, respectively. |
| 25378816 | QoL，Urinary Incontinence | Excellent continence outcomes are observed in patients undergoing double-layered urethrovesical reconstruction. |
| 33941161 | QoL，Urinary Incontinence | The presence of major anastomotic urinary leakage was associated with the achievement of urinary continence, suggesting clinical relevance of its diagnosis by postoperative cystogram. |
| 33508874 | QoL，Urinary Incontinence | The urine loss rate on the day of catheter removal is significantly related to the acquisition of urinary continence. |
| 30929223 | Urinary Incontinence，Intraoperative operation | RS-RARP hastens the recovery of urinary continence after surgery. Prostate volume and severe preoperative IPSS were independent adverse predictors of the return to immediate urinary continence. |
| 30801887 | Urinary Incontinence，Intraoperative operation | The total anatomical reconstruction technique conferred excellent results in the early recovery of urinary continence. |
| 33267679 | Special populations | RARP represents a feasible option to treat PCa in well-selected octogenarian men.R |
| 30375062 | Other | The results showed that transperineal ultrasound-guided perioperative pelvic floor muscle training perioperatively was associated with early recovery of urinary continence after RARP. |
| 27531014 | Other | A high level of physical activity preoperatively was associated with reduced need for sick leave after radical prostatectomy compared to men with lower physical activity. |
| 30946773 | Economy，Prediction | This study highlights different categories of patients at risk who may be important to know in order to develop personalized medical pathways and predictive models in a value-based healthcare. |
| 27933389 | Economy，Hospital&Surgeon | Annual caseload volume of hospitals is the most important factor for improved in-hospital outcomes. |
| 30332593 | Prediction，QoL，Urinary Incontinence | Known predictors of postprostatectomy incontinence, namely bladder neck resection and large prostate volume. Noteworthy, cigarette smoking at the time of RARP was found to be a possible independent risk factor for PPI. |
| 27157376 | Economy，Hospital&Surgeon | This study provides insight into the role of surgeons and hospitals in robot-assisted radical prostatectomy costs. Given the substantial variability, identifying and remedying the root cause of outlier costs may yield substantial benefits. |
| 26065923 | Economy，Comparison of surgical techniques | Cost for RP significantly varies within the nation and in most regions it is significantly greater for RARP than for ORP. ORP in the Northeast is more costly than RARP. |
| 33749767 | Economy，Comparison of surgical techniques | Total cumulative cost in this study was similar between ORP and RARP 1 year post discharge |
| 34268880 | Economy | Reducing the number of robotic instruments used in RARP represented the potentially modifiable factor with the greatest impact on cost reduction. |
| 30143383 | Economy | The robot-assisted procedure was associated with a higher mean cost. |
| 21717434 | Economy | Robotic technology acquisition occurred rapidly in Wisconsin hospitals, and hospitals that acquired a robot had large increases in prostatectomy volume. |
| 33751413 | Economy | A full accounting of the costs of a new technology will depend on when it is used and the payment rate for its use relative to payment rates for substitutes. |
| 32720178 | Anatomic structure，Other prognosis | Postoperative inguinal hernia occurred significantly more frequently in patients with a PMV < 350 cm3 than in patients with a PMV ≥ 350 cm3, and a low psoas muscle volume was an independent risk factor for postoperative inguinal hernia. |
| 28586158 | Anatomic structure，Other prognosis | Preoperative longer membranous urethral length and shorter inner levator distance, but also intraoperative fascia preservation independently improve continence recovery after RARP. The risk calculator could be used to identify patients at high risk of UI. |
| 20708781 | Anatomic structure，Other prognosis | Larger prostate size was associated with increased operative times and blood loss. While these patients appeared to benefit regarding irritative symptoms, recovery of continence was delayed. |
| 32005113 | Prediction，Anatomic structure，QoL，Urinary Incontinence | Membranous urethral length had no effect on baseline continence but had a positive and significant association with continence outcomes over 12 months post RALP. |
| 26579289 | Anatomic structure，Other prognosis | Patients with larger prostates had favourable pathological outcomes after RALP. When controlling for pathological stage, prostate size was not associated with margin positivity. Functionally, neither continence nor potency at 12 months was affected by prostate size. |
| 35474722 | Anatomic structure，Intraoperative operation，Urinary Incontinence | Patients with longer Preserved urethral length in RARP have a significantly higher rate of post-operative urinary continence recovery. |
| 20825759 | Anatomic structure，Intraoperative operation | The holistic preservation of the PVC during RALP is technically feasible. It leads towards an absolute preservation of the periprostatic anatomy that may enhance early functional outcomes. |
| 33574414 | Anatomic structure，Intraoperative operation | Robotic radical prostatectomy did not deteriorate the detrusor’s condition, including compliance and/or involuntary detrusor contraction. |
| 33878204 | Anatomic structure，QoL，Special populations | For patients undergoing RP, giant prostate volume was not associated with adverse HRQOL outcomes. |
| 29991233 | Anatomic structure，QoL，Urinary Incontinence | Continence outcomes were not associated with bladder neck displacement, produced by activity of the puborectal portion of the levator ani muscle, at 3, 6, or 12 months after RARP. |
| 33547552 | Other | A positive 18F-DCFPyL PET/CT scan, positive pathological lymph node status, and a negative surgical margin status were significantly associated with increased odds of having a change of management based on 18F-DCFPyL PET/CT findings. |
| 32591157 | Other prognosis，Special populations | In patients with high-grade locally-advanced PCa, a low iPSA level was associated with a higher risk of disease progression, but not with biochemical recurrence. |
| 32696130 | Other prognosis | A considerable number of men have detectable uPSA values ranging between 0.01 and 0.1ng/ml post-RARP. They can still be followed regularly to avoid patients' anxiety and salvage radiotherapy. Close follow-up is still required. |
| 34725727 | MRI，Pathology | Both [18F]DCFPyL-PET/MRI and mpMRI were only partly able to detect csPCa on a per-segment basis. An accurate detection (90.0%) of the highest GG lesion at patient-level was observed when comparing both [18F]DCFPyL-PET/MRI and mpMRI biopsy advice with the histopathology in the RARP specimen. |
| 31607103 | Prediction，Anatomic structure | The extent of bladder neck elevation after robot-assisted laparoscopic prostatectomy, which can be easily evaluated using cystography, may be a good predictor of the recovery of urinary continence. |
| 26578444 | New technique | The Aalst technique allows the removal of catheters 2 d after RARP and results in spontaneous voiding. Early removal showed no increased rate of urinary leakage, no negative impact on short-term continence and on perineal, urethral or penile pain, and no increase in urinary retention rates. Future studies have to confirm these results with longer follow-up including detailed parameters on return to daily activity. |
| 31673232 | Prediction | The rs145204276 polymorphic genotype of GAS5 can predict the risk of lymph node metastasis. |
| 20615888 | Other | Changes in biomarker expression between RALP and RRP tissue exist at the immunoreactive protein level, but the etiology is unclear |
| 32878251 | Other | H19 single-nucleotide polymorphisms play a role in the perineural invasion of prostate cancer. |
| 32631777 | Focus on RARP | Overall, the costs for SP and MP prostatectomy are comparable. The higher SP cost for consumable surgical materials is offset by the lower cost associated with hospitalization, which was largely due to a shorter hospital stay after SP surgery. |
| 33357990 | Focus on RARP | SP-RPP is a complex procedure for patients with a complex surgical history and high-risk localized PCa with limited alternative therapeutic options. |
| 33160915 | Focus on RARP | Pure single-site SP-EPP was associated with a shorter length of stay as well as a decreased need for postoperative pain medication and narcotic administration in comparison with conventional transperitoneal multiport prostatectomy, with comparable postoperative complications and readmission rate. |
| 32896583 | Focus on RARP | Based on an early experience with SP-RALRP at a high-volume center and a pooled analysis of SP series to date, perioperative and pathologic outcomes appear nearly equivalent compared to standard RALRP. |
| 34145537 | Focus on RARP | There was no difference in patient satisfaction with the results of either the da Vinci® SP or Xi RARP except for the patients' perception on their number of scars, which favored the SP group. |
| 34135173 | Focus on RARP | Extraperitoneal robotic single-port radical prostatectomy can be a treatment option for localized prostate cancer. Although it still has a learning curve, it has advantages for postoperative pain and self-assessed cosmesis. |
| 28128908 | Other treatments，QoL | ICIQ after surgery shows significant differences in favour of brachytherapy, which disappear after 6 months. Both procedures have a serious impact on erectile function, being even greater in the DV group. Differences between groups disappear after 6 months. |
| 30365194 | Prediction | Ultrasensitive PSA after RARP is a useful prognostic indicator of BCR which could guide postoperative risk stratification and layout follow-up scheduling. |
| 31959548 | Focus on RARP | RARP with the da Vinci SP is feasible and safe. |
| 33554284 | Focus on RARP | the technological improvements associated to the increased surgeon's expertise made the transition to the single port safe and effective when compared with previous platforms. |
| 33357994 | Focus on RARP | Despite differences in trocar placement and technology between the two da Vinci consoles, the SP has satisfactory intraoperative performance compared to the Xi. SP surgery can be performed safely and effectively during the initial learning phase. However, longer-term follow-up is needed to provide further evidence on the impact of SP implementation on functional and oncological outcomes. |
| 34847882 | Focus on RARP | Although the cost of robot-assisted radical prostatectomy is higher, compared with the Si system, the Xi system has better perioperative outcomes and can provide similar short-term efficacy and oncology outcomes. |
| 34970758 | MRI | Preoperative magnetic resonance imaging targeted prostate biopsy led to better oncological outcomes and less secondary neurovascular-bundle resection. Young patients with good erectile function could benefit from a preoperative magnetic resonance imaging targeted prostate biopsy before nerve-sparing RARP. |
| 29196816 | postoperative treatment，QoL | Continuing nursing care intervention had significant beneficial effects on urinary functions and quality of life in patients with prostate cancer after RARP. |
| 28687029 | QoL，Urinary Incontinence | The presence of metabolic syndrome could have a significant impact on the early recovery of urinary continence after robot-assisted radical prostatectomy. |
| 34168525 | Other | Aging male symptoms in PCa patients with the late-onset hypogonadism syndrome can expect the same level of improvement as patients without it. |
| 34189707 | Prediction | Along the ABO-bgs, the risk of PSM was increased by group O independently by other standard preoperative factors. |
| 32005115 | QoL | Socio-demographic, cancer-related, health, psychological and typical adverse effect variables were significantly associated with moderate/poor current work ability after robot-assisted laparoscopic prostatectomy, and several health and psychological variables are amenable to identification and treatment by health care providers. |
| 34028165 | Prediction，MRI | Initial PSA value, biopsy GG ≥4, ≥ rT3 disease on mpMRI and miN1 disease on PSMA PET were predictors of early biochemical progression after RARP. |
| 22967037 | Intraoperative operation | An ePLND that identifies patients with lymph node metastasis including the internal iliac packet during RALP provides an accurate pathologic staging and may have survival benefits in high-risk prostate cancer. |
| 34472768 | Special populations，QoL，Urinary Incontinence | Obese can safely undergo RARP with similar continence outcomes comparing to the non-obese men when performed by surgeons with a standardized operative technique. |
| 33572174 | Focus on RARP | This multi-surgeon comparative study confirms the safety of routine same day discharge RARP in terms of perioperative and functional outcomes. |
| 32065277 | Focus on RARP | Implementation of same-day discharge RARP in the context of enhanced recovery after surgery and prehabilitation pathways is safe, reduces cost and does not compromise the post-operative course. |
| 27758147 | Focus on RARP | Same-day discharge is safe and feasible. |
| 32602024 | Focus on RARP | In the near future, the transition to same-day discharge after RALP will evolve due to the continued drive for cost-effective surgical care, pressures to reduce hospital contact during the COVID-19 pandemic and rapid advances in surgical technologies, home monitoring, and virtual communication platforms |
| 31301693 | Focus on RARP | SP-RALP appears to be a safe and feasible approach to performing robotic radical prostatectomy. |
| 31257704 | Focus on RARP | Robot-assisted single-port radical prostatectomy using the da Vinci surgical system is safe and technically feasible. |
| 31010600 | Focus on RARP | The da Vinci SP system single-port robot-assisted radical prostatectomy is safe and feasible, with acceptable operative time and blood loss. |
| 31268734 | biopsy，Supplementary Examination | Robotic-assisted MRI-guided biopsy yields 100% technical success rate with a short MRI room occupation time and high cancer detection rate using one or two cores. |
| 24969055 | Prediction，MRI | RARP in men with high-risk PCa can achieve favorable oncologic and functional outcomes. Preoperative MRI may localize high-grade tumors and improve clinical staging. Extent of nerve sparing is influenced by clinical staging and may balance potency and continence with PSMs. |
| 27990424 | biopsy，Supplementary Examination | MRI/TRUS fusion based target biopsy did not show an advantage in the overall detection rate of clinically significant prostate cancer. |
| 27630337 | biopsy，Supplementary Examination | Targeted prostate biopsy ensured a higher of accuracy of prostate cancer detection and a better performance in discriminating significant from insignificant prostate cancer, when compared to standard untargeted biopsy. Targeted prostate biopsy significantly reduced the risk of Gleason Score up-/down-grading at radical prostatectomy for all histopathological categories. |
| 31363468 | biopsy，Focus on RARP | The current practice of mandating a prostatic biopsy before prostatectomy should be reconsidered in the era of new imaging technology and minimally invasive techniques. Radical prostatectomy could be carried out without the evidence of malignancy. |
| 31619029 | biopsy，Pathology | Targeted biopsy technique significantly reduced the risk of GS 3+4 upgrading at radical prostatectomy, compared to standard biopsy one. The rate of upgrading was significantly associated with Gleason pattern 4 >16%, mostly when cribriform sub-type was present at biopsy specimens. |
| 34131882 | Other prognosis | In patients undergoing RARP as a primary treatment for PCa, the risk of perioperative blood transfusion represented a rare event that was predicted by severe intraoperative bleeding, which was associated with increased BMI as well as with prolonged operating time. |
| 31337353 | Special populations | Prostate cancer patients with underlying CKD had significantly greater risk of postoperative complications, postoperative AKI and urinary complications, and longer hospital stays than those without CKD. The use of RARP significantly shortened hospital stays and reduced complications for these patients. |
| 31287254 | Other | Patients with prostate cancer and a previous surgery for BPH should be managed as naïve patients. |
| 25032194 | Other | Performing RALP for prostate cancer in patients who have had previous transurethral resection of the prostate is a technically demanding procedure and may be potentially associated with a higher perioperative major complication rate in short-term follow-up. |
| 25275059 | Pathology，Prediction | Internal prostate biopsy predicted better prostatectomy Gleason score than outside facility biopsy reports. |
| 33947348 | Pathology | Elements of both high-grade cancer risk (such as BMI) and sampling efficiency (such as percentage of cancer positive biopsy cores) contribute to ISUP grade upgrading. Excluding cases diagnosed as ISUP grade group 1 at biopsy, BCR-free rates were significantly worse in cases with ISUP grade upgrading, highlighting the need for more accurate pathological diagnosis at biopsy. |
| 33604046 | Prediction，Pathology | Patients with biopsy GS 4+4 and 4+3 often exhibit a downgrade to GS 3+4 or less in prostatectomy specimens. The lower percentage of highest GS cores out of positive biopsy cores was associated with downgrade. |
| 31067558 | Pathology，Anatomic structure | arcille's nodes involvement is associated to contemporarily multiple LN metastases in other template locations in high-risk PCa patients. The Marcille's lymphadenectomy would be recommended when planning an ePLND in high-risk PCa. |
| 31673831 | Pathology，BCR | The prognosis of prostate cancer patients with pT2 disease and negative surgical margins is favorable. However, patients with the presence of micro-lymphatic invasion and a pathological Gleason score=4+3 tend to experience biochemical recurrence more often after surgery. |
| 30972506 | Pathology，BCR | PSA level > 20 ng/mL and/or presence of the Gleason pattern 5 component on biopsy are predictive factors for early biochemical recurrence after robot-assisted laparoscopic radical prostatectomy in high-risk prostate cancer patients. |
| 32632897 | Pathology | Upgrading was associated with a worse oncological outcome. Center volume was not associated with pathological accuracy. |
| 34748059 | Pathology | The percentage-positive sentinel lymph nodes found after IT-injection were significantly higher compared to intraprostatic-injection. Significantly more node-positive patients were found using intratumoral-injection, which did not affect metastasis-free survival. Intratumoral-injection failed to detect nodal metastases from non-index satellite lesions. |
| 33008371 | Complications，Prediction，Comparison of surgical techniques | Retropubic radical prostatectomy technique and older age, especially patients over 80 years, are associated with higher incidence for postoperative inguinal hernia development. |
| 34279470 | Complications，Prediction | BMI and PetCO2 may be helpful to recognize the occurrence of Subcutaneous emphysema . |
| 30413390 | Complications，postoperative treatment | Early catheter removal after RARP does not lead to an increase in perioperative complications. |
| 30727795 | Complications，Comparison of surgical techniques | There is a substantial risk for hospital readmission after prostate-cancer surgery, regardless of technique; although major complications are rare. Regardless of surgical technique, attention should be focused on specific types of complications. |
| 32055475 | Complications，Comparison of surgical techniques | Clip erosion is responsible for 8.6% of Vesicourethral anastomotic stenosis (VUS) after RP, takes longer to present than non-caVUS, and was seen more commonly after a robotic RP. VUS recurrence rates are similar for caVUS and non-caVUS. |
| 32588704 | Prediction，Complications | The increase of BMI was a significant predictor of symptomatic lymphocele development in pCa patients submitted to RARP and PLND. |
| 32048341 | Complications | Robot-assisted laparoscopic prostatectomy can be safely carried out in patients with ocular diseases, even those with glaucoma, after precautionary consultation with an ophthalmologist. |
| 26936203 | Complications | Intraperitoneal RARP had an increased risk of small bowel obstruction and abdominal pain in the short term during the first year, but not in the long term, compared to RRP. |
| 21489117 | Complications | The incidence of lymphoceles was higher than anticipated given the believed protective effect of the transperitoneal approach against lymphocele formation. • The risk of lymphocele seemed to increase linearly with the presence of more extensive disease, particularly ECE and nodal involvement. • The benefit of PLND during RARP should be weighed against the elevated risk of lymphocele formation and its potential complications. |
| 26800257 | Complications | If a lymphocele is detected at the 3-month follow-up serial ultrasonography discussing percutaneous external drainage with the patient appears to be wise, as it may prevent the development of a symptomatic lymphocele in two-thirds of such patients. |
| 33102393 | Complications | Acute urine retention post-RARP is an infrequent postoperative complication with no impact on early continence rate. No patient-related factors were associated with the development of acute urine retention. |
| 25906167 | Complications | Transient but significant unilateral visual field defects were found in 28% of the subjects examined. |
| 25484965 | Complications | In RALPs, anastomotic leaks can lead to ileus formation and longer hospital stays. These leaks are associated with a higher average blood loss and transfusion rate. |
| 30975668 | Other | The additional information gained by complete sampling in terms of stage and surgical margin detection is statistically insignificant compared with partial sampling. |
| 32461073 | Salvage RARP | This represents a feasible approach with acceptable peri-operative complications and cancer outcomes. |
| 27347619 | Salvage RARP，Other treatments | Robotic salvage prostatectomy appears to have no significant difference to the open approach with respect to safety and surgical quality as measured by complications, node yield and surgical margins in this retrospective single-institution series. |
| 29737495 | Prediction，Complications | BMI is an independent predictor of grade 3 complications, which are increased by 18.4% for each unit rise. Patients may be stratified preoperatively by BMI into grade 3 risk categories, which include low (normal weight), intermediate (overweight), and high (obese) risk cases. |
| 27981731 | Salvage RARP，Intraoperative operation | The initial series of robot-assisted sRPLND+PLND is presented, wherein we duplicate open surgery with superior nodal counts and decreased morbidity. |
| 32611411 | Salvage RARP，Intraoperative operation | Salvage RARP was safe with acceptable but sub-optimal continence and poor sexual-function and poor oncologic outcomes. One in three men required additional treatment within 12-months. |
| 24314031 | Salvage RARP | Salvage RARP provides oncological control with potential avoidance of systemic non-curative therapy. Complication, incontinence and erectile dysfunction rates are significant but frequently correctable. |
| 34462255 | Salvage RARP | sRARP after proton beam therapy is an applicable procedure, but has a high risk of serious complications. |
| 33997823 | Salvage RARP | Salvage RARP is a feasible procedure for the treatment of locally recurrent prostate cancer in high-volume centres; however, patients should be counselled appropriately as to the different outcomes. |
| 33912513 | Salvage RARP | Robot-assisted salvage radical prostatectomy is a reliable procedure to treat local recurrences after external beam radiotherapy or brachytherapy, reducing the risk of anastomotic strictures and blood loss and improving continence outcomes. |
| 30790014 | Salvage RARP | salvage RP was safe, feasible, and effective using either an open or robot-assisted approach, in experienced hands. Age, preoperative clinical stage, NS procedure, and pathological GS were linked with BCR after sRP. |
| 28373480 | Salvage RARP | S-RaRP is feasible with a low complication rate, good continence rate, and an acceptable potency rate. The short-term oncological outcomes are encouraging. |
| 26328083 | PSM，Prediction | In low-risk prostate cancer, a waiting time of less than six weeks between biopsy and surgery and PSA levels above 5 ng/mL are predictive of high surgical margin positivity after robotic radical prostatectomy. |
| 27638369 | PSM，Intraoperative operation | Surgical margin status alone underestimates the overall quality of surgical resection after RALP because not all capsular violations result in a PSM. Surgeon-guided pathologic review in addition to intraoperative experience may improve oncologic success during the RALP learning curve. |
| 33794533 | Prediction，Complications | Patients with aggressive tumours and higher BMI should be informed about a potentially increased risk for symptomatic lymphocele formation formation. |
| 29633374 | PSA，BCR | Prostate-specific antigen screening might contribute to reducing biochemical recurrence in patients with localized prostate cancer. |
| 23114883 | MRI，Prediction，Supplementary Examination | Although the accuracy was limited, the detection of locally advanced disease improved substantially when MRI was added to routine clinical staging. |
| 30691961 | MRI，Prediction，Anatomic structure | This study confirmed the significance of membranous urethral length for the continence outcome following RARP. |
| 29936567 | MRI，Prediction，Anatomic structure | MRI-determined periprostatic fascia thickness combined with intraoperative fascia preservation score are correlated to postprostatectomy erectile function. Based on the hypothesis that a thicker fascia forms a protective layer for the nerves, we recommend assessing fascia thickness preoperatively to counsel men for the odds of preserving erectile function after RARP. |
| 31450657 | MRI,Prediction，Anatomic structure | Preoperative MRI parameters could predict the bladder neck location on postoperative cystograms and the recovery of urinary incontinence after RALP. |
| 33064316 | MRI，Prediction | Bladder elevation distance, a novel dynamic parameter, was strongly associated with early continence recovery. |
| 32219979 | MRI，Prediction | Presence of a transition zone tumour is an independent risk factor for PSMs after RS-RARP. |
| 31538242 | MRI，Prediction | A promising new strategy to predict post-prostatectomy incontinence through the perfusion quality of pelvic muscle structures with contrast media kinetics. |
| 29472629 | MRI，Prediction | The role of mp-MRI seemed to be crucial in patients with a risk of lymph node invasion <5% as calculated by the Briganti updated nomogram. The presence of extracapsular extension, seminal vesicles invasion, or Gleason pattern 4 at mp-MRI was found to be an independent predictor of lymph node invasion by itself. |
| 28986636 | MRI，Prediction | MRI-derived features, Apparent diffusion coefficient and extraprostatic extension, improve risk stratification of biochemical recurrence. Using mpMRI to stratify prostate cancer patients improves the differentiation between risk groups. Using preoperative mpMRI will help urologists in selecting the most appropriate treatment. |
| 33552571 | Prediction，Complications | In addition to a longer operation time and about twice as many complications, patients with a BMI of ≥33.7 kg/m² had a higher PSM rate after RARP. |
| 27900214 | MRI | Prostate tumours below the detection threshold for MRI (5 mm) most probably represent clinically insignificant tumours, which alone would not necessitate leaving AS in favour of more aggressive therapy. |
| 33644166 | BCR，Prediction | Robotic-assisted RP in pT2+ PCa of worse conditions can provide better BCR-free survival. A surgical technique limiting the PSM in favorable situations is warranted to lower the pT2+ PCa BCR rate. Preoperative PSA cut-off value of 19.09 ng/mL is a predictive factor for BCR. |
| 25879548 | BCR，PSM，Prediction | PSM as well as pathological Gleason sum, PSA, pathological stage and early operative period for this surgeon were the independent predictors of BCR. |
| 31893344 | BCR，PSM | High surgeon volume is an independent factor that lowers the risk of focal PSM. Surgeon volume does not affect non-focal PSM and BCR. Negative as well as focal PSM are not associated with BCR. |
| 30519744 | BCR，PSM | Based on a large case series of RARP, we found PSM focality to be an independent predictor of BCR, with a 1.9- and 3.4-fold risk increase for BCR in case of uPSM and mPSM, respectively. PSM seems to be of particular prognostic relevance when NS has been performed. |
| 23318071 | BCR，PSM | Negative surgical margins resulted in lower biochemical recurrence rates for low-risk and intermediate-risk groups. Multifocal and longer positive margins were associated with higher biochemical recurrence rates compared with unifocal and shorter positive margins. |
| 32333202 | BCR | Patients with 1-2 positive LNs and GS < 8 have low risk for BCR; close observation without immediate adjuvant hormonal therapy can be considered for these patients. |
| 29052761 | BCR | Increased delay to surgery could affect the BCR, as there was a positive association in high-risk group. |
| 32755355 | AI，MRI，Focus on RARP | Overall sensitivity was only minimally improved by use of the AI system. Significant improvement was achieved, however, in the detection of transition zone lesions with use of the AI system at the cost of a mean of 40 seconds of additional reading time. |
| 31984644 | Robot-assisted RPP is a reliable and effective surgical technique that can be employed in the treatment of localized prostate cancer regardless of prostate volume, especially in patients with a history of abdominal surgery. As an additional advantage, PLND can be performed through the same incision. | |
| 30325603 | Prediction，PSM，BCR | Length and location of the PSM and the Gleason score detected in the PSM region could not predict biochemical recurrence according to the results of this present study. However high preoperative PSA value is an independent prognostic factor for biochemical recurrence. |
| 20801579 | Other | |
| 30017351 | Other | |
| 34039340 | Pre-operative internal obturator muscle mass index was not associated with BCR. | |
| 34156193 | Other | |
| 31579118 | Prediction，BCR | Features related to host, tumor, and surgeon volume are associated with the risk of PSM, which is also an independent parameter predicting biochemical recurrence after RARP. The surgical volume of the operating surgeon is an independent factor that decreases the risk of PSM, and, as such, the risk of biochemical recurrence. |
| 34211768 | Other treatments，Special populations | Preoperative stereotactic body radiotherapy before robotic RP in high risk prostate cancer is feasible and safe. The severity of acute genitourinary toxicity with preoperative stereotactic body radiotherapy may be worse than RP alone, while bowel toxicity was mild. |
| 30587172 | Prediction，BCR | Extensive apical PSMs significantly increased the risk of BCR, independently from pT stage, Gleason score and lymph nodes invasion, while focal apical PSMs had no significant effect on BCR. |
| 33289056 | Prediction，BCR | Positive surgical margins are a predictor of BCR. |
| 29128577 | Prediction，BCR | In this cohort tumor volume on magnetic resonance imaging and pathological variables, including Gleason score, staging and positive surgical margins, significantly predicted biochemical recurrence. |
| 33423938 | Prediction | This study developed a novel nomogram that combines PSA, ISUP grade groups, positive cores , and mpMRI-derived extracapsular extension score to predict the probability of lymph node invasion at final pathology in RARP candidates. |
| 31727561 | Prediction | A risk of lymph node invasion > 7% is proposed as cut-off above which e-PLND is recommended. |
| 28645325 | Prediction | Prostate-specific antigen density and biopsy core details have different performance characteristics for the prediction of oncologic outcomes in each NCCN risk group. |
| 24006951 | Prediction | A nomogram to predict LNI in Asian men with prostate cancer. |
| 28853623 | Prediction | Predischarge complications, operative time, and length of hospital stay are associated with readmissions and postdischarge complications after RARP. |
| 31115364 | Prediction | Men with clinically localized prostate cancer, the odds of GS change should be presented, and certain men with high-volume GS 6 or low-volume GS 8 can be counseled with GS 7-based recommendations. |
| 32930971 | Prediction | An intuitive online tool was developed to predict PPI after RARP |
| 33082633 | Other treatments，Local Experience | There is a 50% likelihood of upstaging or upgrading in Indian males with low-risk PCa eligible for AS. |
| 30183609 | Prediction | Low PSA fluctuation rate is associated with higher Gleason score upgrading. |
| 35136291 | Prediction | PSA >20 ng/ml is the single most common criterion for stratification as high-risk PCa. |
| 32972895 | Prediction | A simple and robust nomogram for the prediction of side-specific EPE, which should be used to select patients for nerve-sparing RP. |
| 31489241 | Prediction | In high-volume centres features related to host, tumour and surgeon volume are factors that predict the risk of focal and non-focal PSMs after RARP. |
| 29274670 | Prediction | Preoperative PSA and maximal tumor volume in any biopsy core might be useful clinical predictors of pathologic organ-confined diseasein clinically LAPCa patients in RARP setting. |
| 33672650 | Prediction | Prostatic Systemic Inflammatory Marker was found the sole independent prognostic variable influencing probability of adverse pathology. |
| 25813692 | Supplementary Examination，Other prognosis | MRI prior to RP did not reduce the overall risk for PSMs in this patient cohort. However, at subgroup analysis we observed a possible benefit of MRI in patients with cT1. |
| 34024652 | Supplementary Examination，Prediction | The addition of PSMA-PET to the previously developed nomograms showed substantially improved predictive performance, which suggests that PSMA-PET is a likely future candidate for a modern predictive nomogram. |
| 33129868 | Supplementary Examination，Prediction | Use of mp-MRI tumor stage for prostate cancer risk classification leads to upstaging in 1 of 3 patients. Mp-MRI enables superior detection of nonorgan-confined disease compared with DRE, and should be the preferred tool for determining clinical tumor stage. |
| 29279147 | Supplementary Examination，Prediction | MRI had high diagnostic accuracy for seminal vesicle invasion on histopathology. |
| 28270949 | Other treatments | Approximately two thirds of high-risk PCa patients benefit from RARP without additional RT or ADT. Besides, more than one third of low-risk PCa patients who fit active surveillance criteria would have unfavorable results. |
| 30526642 | Supplementary Examination，New technique | a significant increase in maximal standardized uptake value of the prostate of around 30% between early and late imaging. |
| 23878685 | Supplementary Examination，New technique | Three-T MRI prior to RARP enables the use of extracapsular extension diagnosis to guide decision-making about neurovascular bundle preservation, with comparatively high specificity and negative predictive value. |
| 30863982 | Supplementary Examination，New technique | Transperineal imaging using 3D ultrasound is a promising approach for image guidance during RALRP. Preliminary results suggest this system is comparable to existing guidance systems using transrectal ultrasound. |
| 32739147 | Supplementary Examination，Intraoperative operation | Due to urine radioactivity, 68Ga-PSMA-11 PET/CT performs less than PWAmpMRI on local recurrences. |
| 24397422 | Supplementary Examination | Laparoscopic RP aided by a new-generation 3D display system is associated with shorter operative times, reduced blood loss, and higher early continence rates in comparison with that aided by a 2D display system. |
| 33079250 | Supplementary Examination | 18F-DCFPyL-PET/CT potentially allows for accurate PSMA-targeted biopsy. |
| 29715138 | Supplementary Examination | Targeted biopsy has a high sensitivity for characterization of index lesions, with a good concordance for topographic and Gleason grading accuracy between biopsy and surgical specimens. |
| 28735018 | Supplementary Examination，MRI | A clinically significant prostate cancer (≥5-mm radius, 0.5 cm3) depicted in MRI may be accurately targeted. |
| 28582632 | Supplementary Examination，AI，Pathology | Significant associations were observed between magnetic resonance imaging and digital histopathologic analysis, regardless of prostate anatomy. |
| 22645296 | Supplementary Examination | The hybrid nature of the tracer not only enables surgical guidance but also provides an opportunity to study the correlation between the location of tracer deposits within the prostate and the number and location of preoperatively visualized sentinel nodes. |
| 31176208 | Other treatments | The biochemical recurrence-free survival outcomes of RARP and volumetric modulated arc therapy after a medium-term follow-up period were similar, despite their different patient backgrounds |
| 19196060 | Hospital&Surgeon，Learning curve | In a high-volume center for RALP, urologic oncology fellows can be trained to perform the procedure with no significant adverse impact on patient clinical outcomes. |
| 32257810 | Hospital&Surgeon，Learning curve | The surgeon's experience was the most important influencing factor for both operative time and blood loss. PSM rate was mainly determined by tumor stage rather than by operation experience. |
| 28253500 | Hospital&Surgeon | Hospital volume for intraoperative complications and surgeon volume and extended lymph node dissection for perioperative complications were significantly associated with increased risk of each complication in RARP. |
| 35475154 | Hospital&Surgeon，Prediction | The factors associated with surgeon-reported RARP difficulty were patient BMI and clinical T stage among surgeons with significant RARP experience. |
| 28419326 | Hospital | Robotic surgery accessibility within 30 km would make patients less likely select conventional surgery. The nearer a robot was, the faster the caseload reduction was. |
| 21457071 | Hospital，Economy | Using simple modifications, it is possible that RALRP efficiency can be improved by decreasing its associated times and costs. |
| 30953271 | Hospital，PSM | In high-volume centers, features related to host, tumor biology and surgeon are independent factors associated with the risk of PSM after RARP, which are decreased by the high-volume surgeon. |
| 30253389 | Hospital | A higher number or RPs per year was associated with better outcome regarding quality-related parameters like surgical margin status and blood loss |
| 32328779 | Hospital | Low-intermediate volume PCa centers show similar trends to high-volume centers regarding risk group distributions over time in PCa patients undergoing NS RARP. |
| 25941184 | Hospital | Significant differences exist by race/ethnicity and payer status in accessing RARP-performing hospitals. |
Institutes for Systems Genetics, West China Hospital
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