Basic Information

CXCL8

Full name: C-X-C motif chemokine ligand 8

Gene type: protein coding

HGNC ID: HGNC:6025

Gene location: 4q13.3

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/3576

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:6025

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_000584.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P10145

AlphaFold: https://alphafold.ebi.ac.uk/entry/P10145

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/146930

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=3576

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa04060+3576

Variant resources

Gene	Disease type	Variant type	NCBI dbSNP	Alleles	Variant location
CXCL8	Exudative AMD	2KB Upstream Variant	rs4073	A>C / A>G / A>T	chr4:73740307 (GRCh38.p13)
CXCL8	wAMD	Intron Variant	rs2227306	C>T	chr4:73741338 (GRCh38.p13)
CXCL8	AMD	Intron Variant	rs2227543	C>T	chr4:73742193 (GRCh38.p13)