Basic Information

CCL2

Full name: C-C motif chemokine ligand 2

Gene type: protein coding

HGNC ID: HGNC:10618

Gene location: 17q12

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/6347

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:10618

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_002982.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P13500

AlphaFold: https://alphafold.ebi.ac.uk/entry/P13500

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/158105

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=6347

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa04060+6347

Variant resources

Gene	Disease type	Variant type	NCBI dbSNP	Alleles	Variant location
CCL2		3 Prime UTR Variant	rs13900	C>A / C>G / C>T	chr17:34256892 (GRCh38.p13)
CCL2	AMD	2KB Upstream Variant	rs3760396	G>C / G>T	chr17:34254422 (GRCh38.p13)
CCL2	AMD	Stop Gained	rs4586	T>A / T>C	chr17:34256250 (GRCh38.p13)
CCL2	AMD		rs1024611
CCL2	0.25 (0.04–1.65)	Intron Variant	rs28730833	T>A / T>C	chr17:34255475 (GRCh38.p13)
CCL2	Early AMD		rs2857656