Basic Information

TNF

Full name: tumor necrosis factor

Gene type: protein coding

HGNC ID: HGNC:11892

Gene location: 6p21.33

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/7124

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:11892

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_000594.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P01375

AlphaFold: https://alphafold.ebi.ac.uk/entry/P01375

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/191160

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=7124

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa01523+7124

Variant resources

Gene	Disease type	Variant type	NCBI dbSNP	Alleles	Variant location
TNF	Genotype frequency	2KB Upstream Variant	rs1799964	T>C	chr6:31574531 (GRCh38.p13)
TNF	Genotype frequency	KB Upstream Variant	rs1800629	G>A	chr6:31575254 (GRCh38.p13)
TNF	AMD	2KB Upstream Variant	rs361525	G>A	chr6:31575324 (GRCh38.p13)
TNF	AMD	2KB Upstream Variant	rs1800630	C>A / C>G	chr6:31574699 (GRCh38.p13)
TNF	wAMD	Intron Variant	rs1800610	G>A	chr6:31576050 (GRCh38.p13)
TNF	wAMD	2KB Upstream Variant	rs1799724	C>T	chr6:31574705 (GRCh38.p13)