Basic Information

TLR3

Full name: toll like receptor 3

Gene type: protein coding

HGNC ID: HGNC:11849

Gene location: 4q35.1

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/7098

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:11849

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_003265.3

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/O15455

AlphaFold: https://alphafold.ebi.ac.uk/entry/O15455

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/603029

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=7098

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa04217+7098

Variant resources

Gene	Disease type	Variant type	NCBI dbSNP	Alleles	Variant location
TLR3	AMD	Missense Variant	rs3775291	C>G / C>T	chr4:186082920 (GRCh38.p13)
TLR3	nAMD	2KB Upstream Variant	rs5743303	A>T	chr4:186067699 (GRCh38.p13)
TLR3	nAMD	2KB Upstream Variant	rs5743305	T>A	chr4:186068179 (GRCh38.p13)
TLR3	nAMD	Intron Variant	rs5743312	C>T	chr4:186079102 (GRCh38.p13)
TLR3	nAMD	Missense Variant	rs3775290	C>A / C>T	chr4:186083063 (GRCh38.p13)
TLR3	nAMD	Intron Variant	rs6830345	T>A / T>C / T>G	chr4:186084222 (GRCh38.p13)