Basic Information

APOE

Full name: apolipoprotein E

Gene type: protein coding

HGNC ID: HGNC:613

Gene location: 19q13.32

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/348

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:613

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_000041.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P02649

AlphaFold: https://alphafold.ebi.ac.uk/entry/P02649

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/107741

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=348

Pathway resources

Variant resources

Gene Disease type Variant type NCBI dbSNP Alleles Variant location
APOE Early AMD Missense Variant rs429358 T>C chr19:44908684 (GRCh38.p13)
APOE Early AMD Missense Variant rs7412 C>T chr19:44908822 (GRCh38.p13)
APOE AMD 2KB Upstream Variant rs769446 T>C chr19:44905371 (GRCh38.p13)
APOE AMD 2KB Upstream Variant rs405509 G>T chr19:44905579 (GRCh38.p13)
APOE AMD missense Variant rs440446 C>G / C>T chr19:44905910 (GRCh38.p13）
APOE AMD Intron Variant rs769449 G>A chr19:44906745 (GRCh38.p13)
APOE AMD Intron Variant rs769450 G>A chr19:44907187 (GRCh38.p13) Help
APOE AMD rs439401 C>T chr19:44911194 (GRCh38.p13)
APOE VA improvement after anti-VEGF Missense Variant rs429358, rs7412 T>C;C>T chr19:44908684 (GRCh38.p13)