Basic Information

NOS2

Full name: nitric oxide synthase 2

Gene type: protein coding

HGNC ID: HGNC:7873

Gene location: 17q11.2

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/4843

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:7873

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_000625.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P35228

AlphaFold: https://alphafold.ebi.ac.uk/entry/P35228

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/163730

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=4843

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa00220+4843

Variant resources

Gene Disease type Variant type NCBI dbSNP Alleles Variant location
NOS2 Intron Variant rs2255929 T>A / T>C chr17:27760941 (GRCh38.p13)
NOS2 Synonymous Variant rs1060826 T>A / T>C chr17:27762841 (GRCh38.p13)
NOS2 Intron Variant rs2297515 A>C chr17:27766307 (GRCh38.p13)
NOS2 Intron Variant rs2297516 A>C / A>T chr17:27768704 (GRCh38.p13)
NOS2 Missense Variant rs2297518 G>A chr17:27769571 (GRCh38.p13)
NOS2 Intron Variant rs2248814 A>C / A>G chr17:27773295 (GRCh38.p13)
NOS2 Intron Variant rs2314810 C>A / C>G / C>T chr17:27777084 (GRCh38.p13)
NOS2 Missense Variant rs1137933 G>A / G>T chr17:27778906 (GRCh38.p13)
NOS2 Intron Variant rs4795067 A>G chr17:27779649 (GRCh38.p13)
NOS2 Intron Variant rs944725 C>G / C>T chr17:27782545 (GRCh38.p13)
NOS2 Intron Variant rs17722851 T>A chr17:27783810 (GRCh38.p13)
NOS2 Intron Variant rs3794764 G>A / G>C / G>T chr17:27784402 (GRCh38.p13)
NOS2 Synonymous Variant rs16966563 T>C chr17:27788923 (GRCh38.p13)
NOS2 Intron Variant rs8072199 C>T chr17:27789822 (GRCh38.p13)
NOS2 Intron Variant rs2072324 C>A / C>G chr17:27789870 (GRCh38.p13)
NOS2 Intron Variant rs3794766 C>T chr17:27794895 (GRCh38.p13)
NOS2 Synonymous Variant rs3730014 G>A chr17:27798717 (GRCh38.p13)