Basic Information

KDR

Full name: kinase insert domain receptor

Gene type: protein coding

HGNC ID: HGNC:6307

Gene location: 4q12

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/3791

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:6307

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_002253.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P35968

AlphaFold: https://alphafold.ebi.ac.uk/entry/P35968

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/191306

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=3791

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa01521+3791

Variant resources

Gene Disease type Variant type NCBI dbSNP Alleles Variant location
KDR Intron Variant rs1531289 T>A / T>C / T>G chr4:55089065 (GRCh38.p13)
KDR Mean Visual Acuity Change 2KB Upstream Variant rs2071559 A>C / A>G chr4:55126199 (GRCh38.p13)
KDR Mean Visual Acuity Change Intron Variant rs7671745 G>A / G>C chr4:55090669 (GRCh38.p13)
KDR nAMD N/A rs7691507 T>C chr4:55076834 (GRCh38.p13)
KDR Intron Variant rs12642307 T>C / T>G chr4:55086014 (GRCh38.p13)
KDR Intron Variant rs17709898 A>G chr4:55091556 (GRCh38.p13)
KDR Intron Variant rs12505758 T>C chr4:55100731 (GRCh38.p13)
KDR Intron Variant rs13109660 G>A / G>T chr4:55104513 (GRCh38.p13)
KDR Missense Variant rs1870377 T>A chr4:55106807 (GRCh38.p13)
KDR Intron Variant rs7654599 C>T chr4:55110001 (GRCh38.p13)
KDR Intron Variant rs17085326 C>T chr4:55111209 (GRCh38.p13)
KDR Intron Variant rs2034965 A>G / A>T chr4:55111633 (GRCh38.p13)
KDR Missense Variant rs2305948 C>A / C>T chr4:55113391 (GRCh38.p13)
KDR Intron Variant rs7692791 C>G / C>T chr4:55114072 (GRCh38.p13)
KDR Intron Variant rs2305949 C>A / C>T chr4:55114289 (GRCh38.p13)
KDR Intron Variant rs6837735 C>T chr4:55119648 (GRCh38.p13)
KDR Intron Variant rs1531290 G>A chr4:55120395 (GRCh38.p13)
KDR Intron Variant rs12502008 G>A / G>C / G>T chr4:55124875 (GRCh38.p13)
KDR BCVA improvement in 12m/nAMD Intron Variant rs4576072 T>C chr4:55120071 (GRCh38.p13)
KDR BCVA improvement in 12m/nAMD Intron Variant rs6828477 C>G / C>T chr4:55100634 (GRCh38.p13)
KDR Intron Variant rs10020464 C>A / C>T chr4:55112903 (GRCh38.p13)