Basic Information

ICOS

Full name: inducible T cell costimulator

Gene type: protein coding

HGNC ID: HGNC:5351

Gene location: 2q33.2

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/29851

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:5351

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_012092.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/Q9Y6W8

AlphaFold: https://alphafold.ebi.ac.uk/entry/Q9Y6W8

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/604558

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=29851

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa04514+29851

Variant resources

Gene	Disease type	Variant type	NCBI dbSNP	Alleles	Variant location
ICOS		3 Prime UTR Variant	rs10932037	C>T	chr2:203960623 (GRCh38.p13)
ICOS	AMD	3 Prime UTR Variant	rs10183087	A>C / A>G	chr2:203959601 (GRCh38.p13)