Basic Information

FLT1

Full name: fms related receptor tyrosine kinase 1

Gene type: protein coding

HGNC ID: HGNC:3763

Gene location: 13q12.3

Gene resources

NCBI: https://www.ncbi.nlm.nih.gov/gene/2321

Alliance of genome: https://www.alliancegenome.org/gene/HGNC:3763

MANE select: https://www.ncbi.nlm.nih.gov/gene/?term=NM_002019.4

Protein resources

UniProt/Swiss-Prot: https://www.uniprot.org/uniprot/P17948

AlphaFold: https://alphafold.ebi.ac.uk/entry/P17948

MEME motif:

Clinical resources

OMIM: https://www.omim.org/entry/165070

dbVar: https://www.ncbi.nlm.nih.gov/dbvar?LinkName=gene_dbvar&from_uid=2321

Pathway resources

KEGG pathway: https://www.genome.jp/pathway/hsa04010+2321

Variant resources

Gene Disease type Variant type NCBI dbSNP Alleles Variant location
FLT1 Exudative AMD responds to anti-VEGF vs non-responder Intron Variant rs12877323 T>A / T>C / T>G chr13:28305784 (GRCh38.p13)
FLT1 Intron Variant rs2281827 C>G / C>T chr13:28427584 (GRCh38.p13)
FLT1 Intron Variant rs3936415 G>A chr13:28345193 (GRCh38.p13)
FLT1 Intron Variant rs7337610 T>A / T>C / T>G chr13:28388529 (GRCh38.p13)
FLT1 Intron Variant rs7981680 C>A / C>G chr13:28319733 (GRCh38.p13)
FLT1 Intron Variant rs9554320 A>C / A>G / A>T chr13:28312790 (GRCh38.p13)
FLT1 Intron Variant rs9554322 G>A / G>C / G>T chr13:28339694 (GRCh38.p13)
FLT1 Intron Variant rs9943922 T>C chr13:28420518 (GRCh38.p13)