Gene Type Age Female/Male SNP OR CL P-value PMID Link
APOE Early AMD 70±47 210/203 rs429358 0 0 1.97E-01 29851526 View
Early AMD 67.2±7.5 233/130 33467888
Control 60.1±5.6 4105/3612 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
TGFB2 AMD 71.9±8.6 63/48 rs900 1.21 (0.73-.00) 4.43E-01 24303777 View
TGFB2 Control 71.2±6.6 45/51 rs900 1.21 (0.73-.00) 4.43E-01 31614353 View
CFH wet AMD 75.5±7.5 75/88 rs3753394 1.65 (1.19-.28) 2.00E-03 31614353 View
CFH Control 73.1±6.5 83/72 rs3753394 1.65 (1.19-.28) 2.00E-03 18421087 View
TLR3 AMD 70.3±8.8 34/62 rs5743303 1.93 (0.92-4.06) 8.00E-02 18421087 View
TLR3 PCV 69.5±9.4 44/48 rs5743303 1.93 (0.92-4.06) 8.00E-02 24535857 View
TLR3 Control 67±9.5 53/43 rs5743303 1.93 (0.92-4.06) 8.00E-02 24535857 View
MMP2 AMD rs243865 0.426 (0.178-.017) 5.50E-02 24535857 View
FZD4 AMD 78.9±7.0 154/89 rs10898563 0.95 (0.72-.25) 7.10E-01 26333112 View
CFH AMD 73±8.5 23/44 rs1061170 0 0 5.00E-01 21282580 View
Control 66.3±9.5 586/466 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFH Control 72±8.7 52/55 rs1061170 0 0 5.00E-01 17151483 View
CFH Advanced AMD 79.1±9.4 399/345 rs1061170 2.45 (2.11-2.84) 1 17151483 View
CFH Control 74.4±7.1 229/148 rs1061170 2.45 (2.11-2.84) 21402993 View
CFH Advanced AMD 70.2±5.1 328/263 rs1061170 2.45 (2.11-2.84) 21402993 View
CFH Control 67.0±4.3 76/56 rs1061170 2.45 (2.11-2.84) 21402993 View
ULK1 Control 74.1±6.3 109/52 rs10902469 1.34 (0.97-.86) 9.34E-01 21402993 View
ULK1 wet AMD 78.4±6.9 155/70 rs10902469 1.34 (0.97-.86) 9.34E-01 33172148 View
SERPING1 AMD rs1005510 1.49 (1.18-1.88) 2.60E-03 33172148 View
SERPING1 AMD 75.3±7.7 90/110 rs1005510 0.87 (0.64-.2) 4.00E-01 20606025 View
SERPING1 PCV 68.5±9.0 71/162 rs1005510 0.87 (0.64-.2) 4.00E-01 25800435 View
Control 78.4±4.1 929/572 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
SERPING1 Control 74.3±7.6 154/121 rs1005510 0.87 (0.64-.2) 4.00E-01 25800435 View
ACE AMD 0 0 6.00E-02 25800435
CFH AMD 69.5±8.5 199/154 rs1061170 0 0 4.35E-01 12099691 View
CFH Early AMD 73.4±7.04 83/73 rs1061170 1.35 (0.73-.53) 3.40E-01 23842101 View
CFH Advanced AMD 76.1±7.47 42/35 rs1061170 1.35 (0.73-.53) 3.40E-01 18203751 View
P2X7 AMD 79.5±7.8 rs17525809 0.9697 0 8.70E-01 18203751 View
P2X7 Control 78.4±7.4 rs17525809 0.9697 0 8.70E-01 23303206 View
P2X7 AMD 71.32±8.9 rs17525809 0.9697 0 8.70E-01 23303206 View
P2X7 Control 68.84±8.6 rs17525809 0.9697 0 8.70E-01 23303206 View
C3 AMD rs147859257 3.65 (2.66-.00) 8.80E-16 23303206 View
Control 74.9±8.0 1086/847 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFH AMD rs800292 2.79 (1.67-.65) 1.10E-04 24036950 View
CXCL8 CNV 71.1±7.5 60/76 rs2227306 0 0 6.00E-02 15870199 View
CXCL8 Geographic Atrophy 71.4±6.4 74/102 rs2227306 0 0 6.00E-02 18235016 View
CXCL8 Control 71.5±6.9 82/98 rs2227306 0 0 6.00E-02 18235016 View
SERPINF1 wet AMD 70.9±11.3 73/95 rs12150053 1.22 (0.89-.68) 2.20E-01 18235016 View
SERPINF1 Control 74.4±9.6 96/134 rs12150053 1.22 (0.89-.68) 2.20E-01 21174599 View
ARMS2/LOC387715 AMD 76.8±7.7 396/214 rs10490924 5.73 (3.07-0.71) 3.13E-08 21174599
ARMS2/LOC387715 Control 66.7±8.1 148/111 rs10490924 5.73 (3.07-0.71) 3.13E-08 16642439
ERCC2 AMD 75±8 67/53 rs1799793 0.9 (0.55-.47) 6.70E-01 16642439 View
ERCC2 Control 73±10 114/91 rs1799793 0.9 (0.55-.47) 6.70E-01 20375340 View
Control 66.9±6.8 536/540 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFH AMD 73.3±9.7 58/46 rs1061170 0 0 20375340 View
CFH Control 71.6±6.7 66/65 rs1061170 0 0 16774956 View
CFH Early AMD 61/72 rs1061170 0 0 9.00E-04 16774956 View
CFH Control 82/98 rs1061170 0 0 9.00E-04 18784628 View
VEGFA AMD rs3024994 0 0 7.70E-01 18784628 View
C2 AMD rs9332739 0 0 2.20E-02 23149126 View
CFB Control 73±7 88/103 rs4151667 0.46 (0.23-0.92) 2.80E-02 17576744 View
CFB AMD 76±8 79/137 rs4151667 0.46 (0.23-0.92) 2.80E-02 32762675 View
CFB wet AMD 75±8 59/118 rs4151667 0.46 (0.23-0.92) 2.80E-02 32762675 View
CFB Dry AMD 81±7 20/19 rs4151667 0.46 (0.23-0.92) 2.80E-02 32762675 View
Control 55.7±5.2 846/659 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
VEGFA CNV 71.62±8.4 49/45 rs833061 0 0 9.60E-02 32762675 View
C5 AMD 78.0±9 233/152 rs10985126 0 0 8.82E-02 24522370 View
C5 Control 74±6 110/89 rs10985126 0 0 8.82E-02 20022638 View
CRP Control 74.7±6.1 342/301 rs1205 0.99 (0.86-1.14) 8.80E-01 20022638 View
CRP Early AMD 74.6±5.9 295/279 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
CRP Advanced AMD 79.5±7.2 100/52 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
CRP Control 75.7±7.8 157/105 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
CRP Advanced AMD 80.4±6.9 231/196 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
CRP Control 74.8±8.0 144/104 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
CRP Advanced AMD 77.9±7.4 746/402 rs1205 0.99 (0.86-1.14) 8.80E-01 28750115 View
Control 58.2±11.1 1065/900 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
C3 AMD 75.73±6.856 64/56 rs2230199 0 0 3.10E-03 21850184 View
C3 Control 81.14±5.640 72/68 rs2230199 0 0 3.10E-03 24519512 View
IL1B AMD 78.8±7.9 312/166 rs16944 1.09 (0.91to1.32) 3.60E-01 24519512 View
IL1B Control 69±9.7 306/249 rs16944 1.09 (0.91to1.32) 3.60E-01 18310311 View
C3 AMD 76±8 447/271 rs2230199 1.2 (1.1-1.3) 2.00E-04 18310311 View
C3 Control 70±5.9 714/532 rs2230199 1.2 (1.1-1.3) 2.00E-04 24736606 View
C3 AMD 80±6.4 402/354 rs2230199 1.2 (1.1-1.3) 2.00E-04 24736606 View
C3 Control 77±6.5 515/457 rs2230199 1.2 (1.1-1.3) 2.00E-04 24736606 View
PLEKHA1 AMD 76.32±6.90 545/303 rs4146894 0 0 1.50E-10 24736606 View
Control 56.8±9.6 984/977 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
PLEKHA1 Control 76.21±5.28 377/235 rs4146894 0 0 1.50E-10 16174643 View
VEGFA wet AMD 78.35±6.9 81/70 rs833061 0 0 5.64E-01 16174643 View
VEGFA Control 70.51±6.386 52/39 rs833061 0 0 5.64E-01 23971975 View
HTRA1 AMD 73.30±7.73 191/150 rs1049331 6.636 (3.557-2.378) 2.69E-09 23971975 View
HTRA1 Control 75.40±8.25 118/80 rs1049331 6.636 (3.557-2.378) 2.69E-09 23478260 View
AMD 1347/ 23478260
HTRA1 Control 66±11 79/59 rs11200638 1.78 (1.06-.99) 3.00E-02 26028346 View
HTRA1 AMD 79±7 76/69 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 Control 77±4 105/88 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 AMD 79±5 195/135 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
APOE Dry AMD rs7412 0 0 1.20E-02 23326517 View
HTRA1 Control 77±8 344/224 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 AMD 77±8 172/112 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 Control 64±12 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 AMD 75±14 27/19 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 Control 74±9 540/381 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
HTRA1 AMD 78±8 468/337 rs11200638 1.78 (1.06-.99) 3.00E-02 18718667 View
VEGFA AMD rs833068 0 0 2.24E-01 18718667 View
SELE AMD rs4786 0 0 6.60E-01 20471686 View
MMP9 PCV 66±9.44 84/167 rs17576 0.9903 (0.7186-.365) 9.52E-01 21521525 View
MMP9 AMD 67±9.17 56/101 rs17576 0.9903 (0.7186-.365) 9.52E-01 5162123 View
APOE wet AMD rs7412 0 0 1.20E-02 View
MMP9 Control 68±7.15 80/124 rs17576 0.9903 (0.7186-.365) 9.52E-01 5162123 View
CCL2 AMD 65±7 37/74 rs1024611 2.56 (1.24-.29) 1.00E-02 5162123 View
CCL2 Control 61±13 21/39 rs1024611 2.56 (1.24-.29) 1.00E-02 29664944 View
mtDNA AMD 76 187/125 mt16111 2.9 (1.38-6.11) 5.00E-03 29664944
mtDNA Control 71 688/661 mt16111 2.9 (1.38-6.11) 5.00E-03 25592585
mtDNA AMD 69.2 21/16 mt16111 2.9 (1.38-6.11) 5.00E-03 25592585
mtDNA Control 67.8 211/219 mt16111 2.9 (1.38-6.11) 5.00E-03 25592585
mtDNA AMD 69 46/21 mt16111 2.9 (1.38-6.11) 5.00E-03 25592585
mtDNA Control 67.1 282/139 mt16111 2.9 (1.38-6.11) 5.00E-03 25592585
VEGFA Dry AMD 71.1±7.5 46/58 rs2010963 0 0 2.30E-01 25592585 View
wet AMD 65.6±8.6 56/92 21541275
APOE Control rs7412 0 0 1.20E-02 View
VEGFA wet AMD 71.4±6.4 36/50 rs2010963 0 0 2.30E-01 18378209 View
VEGFA Control 71.5±6.9 82/98 rs2010963 0 0 2.30E-01 18378209 View
CFH AMD 78.4±8.65 330/227 rs1061170 3.62 (2.56-.14) <0.0001 18378209 View
CFH Control 69.1±9.76 308/243 rs1061170 3.62 (2.56-.14) <0.0001 17464302 View
CFH AMD 78.6±6.13 13/14 rs1061170 3.62 (2.56-.14) <0.0001 17464302 View
CFH Advanced AMD 75.6±7.4 4.3 (1.70-3.58) 1.18E-03 17464302 View
CFH Control 77.2±6.0 4.3 (1.70-3.58) 1.18E-03 26501415 View
DAPL1 Advanced AMD 77.68±7.78 1958/1271 rs17810398 1.332 (1.187-.496) 1.15E-06 26501415 View
DAPL1 Control 73.14±7.49 rs17810398 1.332 (1.187-.496) 1.15E-06 25680934 View
TLR3 Control 65.4±10.3 114/75 rs3775291 1.02 (0.92-.12) 7.40E-01 25680934 View
TOMM40 AMD 74.9±7.0 679/857 rs2075650 0 0 P>0.05 View
TLR3 AMD 80.1±7.6 67/64 rs3775291 1.02 (0.92-.12) 7.40E-01 19628747 View
TLR3 Control 66.8±4.2 109/92 rs3775291 1.02 (0.92-.12) 7.40E-01 19628747 View
TLR3 AMD 68.8±5.0 167/115 rs3775291 1.02 (0.92-.12) 7.40E-01 19628747 View
TLR3 Control 75.2±7.4 344/224 rs3775291 1.02 (0.92-.12) 7.40E-01 19628747 View
TLR3 AMD 75.3±7.6 172/112 rs3775291 1.02 (0.92-.12) 7.40E-01 19628747 View
BTBD16 AMD rs986960 0 0 3.89E-01 19628747 View
SYN3 AMD 64±8.75 60/130 rs9621532 0.8397 (0.3523-.001) 6.93E-01 18207215 View
SYN3 PCV 67±9.29 50/86 rs9621532 0.8397 (0.3523-.001) 6.93E-01 22171703 View
SYN3 Control 68±9.18 69/112 rs9621532 0.8397 (0.3523-.001) 6.93E-01 22171703 View
RAD51B Early AMD 73±12 171/83 rs8017304 0 0 7.45E-01 22171703 View
TOMM40 Control 61.2±10.0 139/65 rs2075650 0 0 P>0.05 View
RAD51B wet AMD 76±11 157/87 rs8017304 0 0 7.45E-01 31191752 View
RAD51B Control 53 592/350 rs8017304 0 0 7.45E-01 31191752 View
ARMS2 PCV 73.6±7.4 14/62 rs10490924 0 0 5.70E-06 31191752 View
ARMS2 AMD 75.7±7.3 15/58 rs10490924 0 0 5.70E-06 17692272 View
ARMS2 Control 71.2±5.2 31/63 rs10490924 0 0 5.70E-06 17692272 View
HTRA1 AMD 35/35 rs11200638 3.03 0 9.80E-03 17692272 View
HTRA1 Control 15/15 rs11200638 3.03 0 9.80E-03 22930722 View
TLR3 AMD rs3775291 1.093 (0.682-13753) 9.30E-01 19381347 View
CFH Early AMD 61.0±13.7 90/27 rs1061170 0 0 18753640 View
CFH AMD 73.3±6.9 66/27 rs1061170 0 0 17003406 View
CFH Geographic Atrophy 72.8±6.2 rs1061170 0 0 17003406 View
CFH AMD 67.1±12.3 175/61 rs1061170 0 0 17003406 View
CFH Control 70.0±8.0 84/60 rs1061170 0 0 17003406 View
CXCL8 AMD 75.0±7.6 397/324 rs2227306 1.39 (1.19-.62) 4.14E-05 17003406 View
CXCL8 Control 69.2±11.1 356/304 rs2227306 1.39 (1.19-.62) 4.14E-05 23840568 View
VEGFA AMD 59 44/44 rs3025039 1.1 (0.53-2.25) 9.34E-01 23840568 View
VEGFA Control 50 41/54 rs3025039 1.1 (0.53-2.25) 9.34E-01 26466227 View
FPR1 AMD rs7253284 0 0 6.80E-02 26466227 View
CFH AMD 72.13±5.77 39/48 rs1061170 0.44 (0.22-.87) <0.05 25277308 View
AMD 75.8±8.3 421/196
CFH Control 62.80±5.22 40/40 rs1061170 0.44 (0.22-.87) <0.05 24995509 View
ARMS2/LOC387715 AMD 60.1±5.8 296/681 rs10490924 0 0 <0.001 24995509
ARMS2/LOC387715 Control 60.2±5.9 681/390 rs10490924 0 0 <0.001 17210852
CFH AMD 78.7±6.5 650/336 rs1061170 2.74 (2.36-.18) 1.66E-45 View
CFH Control 78.3±5.1 483/313 rs1061170 2.74 (2.36-.18) 1.66E-45 22666427 View
CFH AMD 69.40±7.64 52/82 rs1061170 0 0 1.85E-01 22666427 View
IGF1R Control 66.3±0.29 104/105 rs2872060 0 0 1.20E-01 19223990 View
Control 69.0±7.9 750/510
IGF1R Drusen 68.6±0.27 213/141 rs2872060 0 0 1.20E-01 22058336 View
IGF1R Advanced AMD 69.4±0.30 178/123 rs2872060 0 0 1.20E-01 22058336 View
CFH AMD 76.5±7.6 374/210 rs3753394 0 0 7.58E-01 22058336 View
CFH Control 66.1±9.1 140/108 rs3753394 0 0 7.58E-01 17724217 View
CFH AMD 69.4±7.3 75/93 rs1061170 0 0 2.12E-01 17724217 View
CX3CR1 AMD rs3732378 3.16 (0.34-28.93) 3.89E-01 24080590 View
ARMS2 AMD rs10490923 0.46 (0.22-.95) 3.30E-02 25050486 View
HTRA1 AMD rs11200638 2.2 (1.63-2.98) 5.30E-15 18436811 View
EXOC5 wet AMD 75.3±7.9 26/47 rs75165563 3.28 (2.02-.33) 7.49E-07 17426452 View
EXOC5 wet AMD 73.6±8.3 124/237 rs75165563 3.28 (2.02-.33) 7.49E-07 30054556 View
CFH wet AMD 70.8±6.9 179/317 rs1061170 0 0 6.85E-01 View
EXOC5 wet AMD 73.5±8.3 35/87 rs75165563 3.28 (2.02-.33) 7.49E-07 30054556 View
EXOC5 wet AMD 72.9±8.4 109/254 rs75165563 3.28 (2.02-.33) 7.49E-07 30054556 View
POLR1C AMD rs699946 0 0 7.70E-01 30054556 View
CFH AMD 81.5±6.3 58/46 0 0 1.80E-01 24652518 View
LCN9 AMD rs200437673 0 0 1.50E-11 21558292 View
HTRA1 wet AMD 75.5±7.5 75/88 rs11200638 5.2 (3.24-.35) 1.74E-12 31367973 View
HTRA1 Control 73.3±6.5 92/91 rs11200638 5.2 (3.24-.35) 1.74E-12 18316707 View
MCUB Advanced AMD 78 663/565 rs13101299 1.138 0 2.37E-01 18316707 View
MCUB Control 74 454/371 rs13101299 1.138 0 2.37E-01 18685559 View
CFH AMD 71.3±8.9 rs1061170 2.43 0 18685559 View
CFH Control 65.3±5.4 600/576 rs1061170 0 0 6.85E-01 29259020 View
CFH Control 68.8±8.6 rs1061170 2.43 0 19001225 View
TEK AMD 75.2±7.6 93/121 rs10967760 0.79 (0.61-1.02) 7.00E-02 19001225 View
TEK PCV 68.5±9.0 73/163 rs10967760 0.79 (0.61-1.02) 7.00E-02 32152144 View
TEK Control 70.9±11.0 266/167 rs10967760 0.79 (0.61-1.02) 7.00E-02 32152144 View
HLA AMD 119/81 0.39 (0.21-.73) 3.00E-03 32152144
HLA Control 116/76 0.39 (0.21-.73) 3.00E-03 15851575
CFH wet AMD 68.0±9.4 60/84 rs1061170 2.63 (1.36-5.07) 3.00E-03 15851575 View
CFH Control 66.3±8.7 62/64 rs1061170 2.63 (1.36-5.07) 3.00E-03 19187590 View
CFH Control rs800292 0.48 (0.34-.67) <0.0001 19187590 View
CFH AMD rs800292 0.48 (0.34-.67) <0.0001 22247456 View
CYP4F2 wet AMD 77±61-92 71/33 rs2108622 0 0 2.86E-01 29259020 View
CFH Control 65.7±7.8 77/84 rs1410996 1.71 (0.82-.54) <0.001 22247456 View
CFH wet AMD 66.6±8.4 48/69 rs1410996 1.71 (0.82-.54) <0.001 19850835 View
FRK AMD 69.4±8.9 111/189 rs1999930 0 0 2.22E-01 19503741 View
FRK PCV 66.8±9.6 112/188 rs1999930 0 0 2.22E-01 25228097 View
FRK Control 65.1±9.5 158/142 rs1999930 0 0 2.22E-01 25228097 View
SERPINF1 AMD 70.6±9.8 37/59 rs1136287 1.4 (0.74-.67) 3.00E-01 25228097 View
SERPINF1 Control 73.9±10.4 38/60 rs1136287 1.4 (0.74-.67) 3.00E-01 30142832 View
CFH AMD 1.91 (1.21-3.07) 3.00E-03 30142832 View
NQO1 AMD 72.8±8.4 185/96 rs1800566 0.95 (0.27-3.28) >0.05 17210858 View
CYP4F2 wet AMD rs2108622 0 0 2.86E-01 34577897 View
NQO1 Dry AMD 74.3±8.7 67/34 rs1800566 0.95 (0.27-3.28) >0.05 23276910 View
NQO1 wet AMD 72.5±8.0 118/62 rs1800566 0.95 (0.27-3.28) >0.05 23276910 View
NQO1 Control 71.7±10.2 70/35 rs1800566 0.95 (0.27-3.28) >0.05 23276910 View
C3 Control 67.52±8.31 2358/1697 rs2230199 1.27 (1.09-.49) <0.05 23276910 View
C3 Early AMD 75.05±8.70 285/191 rs2230199 1.27 (1.09-.49) <0.05 19168221 View
C3 Advanced AMD 81.99±8.20 70/36 rs2230199 1.27 (1.09-.49) <0.05 19168221 View
C3 Control 74.11±6.34 90/83 rs2230199 1.27 (1.09-.49) <0.05 19168221 View
C3 Early AMD 76.50±7.21 60/29 rs2230199 1.27 (1.09-.49) <0.05 19168221 View
C3 Advanced AMD 78.73±7.69 154/114 rs2230199 1.27 (1.09-.49) <0.05 19168221 View
CFH AMD rs1061170 0 0 1.01E-43 19168221 View
Control 63.7±7.6 138/63 21541275
CYP4F2 Control 75±67-94 134/67 rs2108622 0 0 2.86E-01 34577897 View
C2 AMD rs9332739 0.36 (0.23-.56) 4.14E-06 24036949 View
UBE3D AMD rs7739323 0.742 (0.629,0.875) 1.46E-09 16518403 View
SERPINF1 Geographic Atrophy 71.1±7.5 46/58 rs1136287 0 0 8.70E-01 25872646 View
SERPINF1 wet AMD 71.4±6.4 36/50 rs1136287 0 0 8.70E-01 18226801 View
SERPINF1 Control 71.5±6.9 41/49 rs1136287 0 0 8.70E-01 18226801 View
SERPING1 AMD rs2511989 0.67 (0.56-0.80) 1.77E-05 23745581 View
ESR1 AMD 996/ rs2234693 0 0 9.20E-01 20576771 View
CFI AMD 69.4±8.9 111/189 rs10033900 0.973 (0.767-.235) 8.23E-01 18359774 View
CFI PCV 66.8±9.6 112/188 rs10033900 0.973 (0.767-.235) 8.23E-01 24732209 View
AMD 69±1.3 17/31 34577897
CFI Control 65.1±9.5 158/142 rs10033900 0.973 (0.767-.235) 8.23E-01 24732209 View
CDKN2B-AS1 PCV 65±8.45 60/117 rs1333040 1.26 (0.92-.73) 1.46E-01 24732209
CDKN2B-AS1 AMD 67±9.46 47/84 rs1333040 1.26 (0.92-.73) 1.46E-01 21896860
CDKN2B-AS1 Control 68±9.17 69/113 rs1333040 1.26 (0.92-.73) 1.46E-01 21896860
CFH CNV 64±6.6 90/68 rs3753394 0 0 2.76E-02 21896860 View
CFH drusen 68±8.5 41/39 rs3753394 0 0 2.76E-02 20523265 View
CFH Control 63±7.8 119/101 rs3753394 0 0 2.76E-02 20523265 View
CFHR1/CFHR3 AMD 0 0 3.13E-01 20523265
CFH AMD 72.6±7.6 112/43 rs1061170 2.45 (1.11-5.42) 0.00E+00 26045838 View
CFH Control 71.1±7.3 34/117 rs1061170 2.45 (1.11-5.42) 0.00E+00 17050575 View
Control 53.2±1.6 27693409
TNFRSF10A AMD 74.3±8.7 387/977 rs13278062 0.79 (0.73-.86) 1.98E-08 17050575 View
TNFRSF10A Control 45.3±15.4 1522/1535 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A AMD 74±8.5 84/239 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A Control 72.5±9.4 46/69 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A AMD 70.8±8.7 84/156 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A Control 65.7±5.0 70/81 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A AMD 71.6±9.1 161/272 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
TNFRSF10A Control 74.3±7.6 121/121 rs13278062 0.79 (0.73-.86) 1.98E-08 22930721 View
FBN2 AMD rs154001 1.1 (1.05,1.15) 3.79E-10 22930721 View
TNF wet AMD 69.8±5.8 82/108 rs361525 0 0 6.20E-01 24899048 View
CFH AMD 68±55-81 1458/1102 rs1061170 10.2 0 8.00E-01 27693409 View
TNF Control 71.5±6.9 82/98 rs361525 0 0 6.20E-01 21060270 View
CFI Advanced AMD 71/37 rs10033900 1.2 (0.6-.4) 5.19E-01 21060270 View
CCR3 Control 69.6±9.8 61/42 0.93 (0.06-5.21) 9.60E-01 22815349 View
CCR3 AMD 79.4±8.3 63/68 0.93 (0.06-5.21) 9.60E-01 21273533 View
CFH Advanced AMD 80.3±6.9 rs1061170 0 0 <0.0005 21273533 View
CFH Control 75.8±7.8 rs1061170 0 0 <0.0005 16431947 View
PON1 AMD 77 414/623 rs854560 0 0 7.80E-02 16431947 View
PON1 Control rs854560 0 0 7.80E-02 20042177 View
ACO1 Control 68.20±10.95 82/23 rs867469 2.07 (1.21-.57) <0.05 20042177 View
ACO1 AMD 72.46±8.51 197/92 rs867469 2.07 (1.21-.57) <0.05 22331484 View
AMD 200/153 24346170
CCT3 AMD 78.0±7.4 1210/848 rs12138564 0 0 1.38E-05 22331484 View
RBPJL AMD 77.5 338/489 rs200998587 0.986 (0.774-.257) 9.12E-01 29852030 View
RBPJL Control 79.8 338/489 rs200998587 0.986 (0.774-.257) 9.12E-01 29565837 View
CFH AMD rs1061170 1.49 (1.09-2.02) <0.0001 29565837 View
CFH AMD 62.4±6.9 rs1061170 1.99 (1.77-2.22) 4.40E-30 26961928 View
CFH Control 62.4±6.9 rs1061170 1.99 (1.77-2.22) 4.40E-30 24287500 View
CFH AMD 72.2±8.6 23/60 rs800292 0 0 3.98E-01 24287500 View
VEGFA wet AMD rs2010963 0 0 3.08E-01 21811649 View
CFH Advanced AMD 425/352 rs1061170 0 0 <0.0001 25525324 View
CFH Early AMD 1135/853 rs1061170 0 0 <0.0001 24498017 View
ABCA1 AMD 8.6 (0.5-59.8) 0.00E+00 View
CYP4F2 Early AMD 66 133/57 rs2108622 0 0 6.48E-01 25279119 View
CYP4F2 wet AMD 76 122/59 rs2108622 0 0 6.48E-01 27652291 View
CYP4F2 Control 52 161/49 rs2108622 0 0 6.48E-01 27652291 View
VEGFA AMD 74.5±7.66 108/158 rs1570360 0.93 (0.30-.84) 1.00E+00 27652291 View
CFB AMD 74.5±7.66 108/158 rs4151667 0.461 (0.162-1.278) 5.90E-02 28845124 View
CFB Control 72.27±6.43 88/106 rs4151667 0.461 (0.162-1.278) 5.90E-02 31528764 View
MMP2 Early AMD 67 166/124 rs2285053 0 0 5.40E-01 31528764 View
ABCA1 AMD 98/43 8.6 (0.5-59.8) 0.00E+00 11818392 View
MMP2 Control 68 316/210 rs2285053 0 0 5.40E-01 28944191 View
MMP2 Geographic Atrophy 73 rs2285053 0 0 5.40E-01 28944191 View
HTRA1 AMD 67.3±8.4 47/33 rs11200638 0 0 28944191 View
HTRA1 Control 68.2±7.8 46/39 rs11200638 0 0 34727349 View
IL1B Control 67.24±9.53 204/198 rs1143627 1.37 (0.91-.07) 1.20E-01 34727349 View
IL1B AMD 73.53±9.00 225/172 rs1143627 1.37 (0.91-.07) 1.20E-01 34132166 View
IL1B Advanced AMD 74.58±8.63 144/132 rs1143627 1.37 (0.91-.07) 1.20E-01 34132166 View
IL1B Dry AMD 72.67±9.55 97/70 rs1143627 1.37 (0.91-.07) 1.20E-01 34132166 View
IL1B wet AMD 74.14±8.56 128/102 rs1143627 1.37 (0.91-.07) 1.20E-01 34132166 View
ABCA4 AMD rs749025898 1.75 (0.378-8.097) 4.69E-01 11818392 View
C2 AMD 67.6±10.2 216/233 rs2734335 1.04 (0.89-.23) 6.19E-01 26247461 View
C2 Control 70.8±9.3 510/515 rs2734335 1.04 (0.89-.23) 6.19E-01 23557739 View
SIRT1 Early AMD 74±12 211/97 rs3818292 0 0 2.91E-01 23557739 View
SIRT1 wet AMD 77±10 266/145 rs3818292 0 0 2.91E-01 View
SIRT1 Control 74±7 136/89 rs3818292 0 0 2.91E-01 View
HTRA1 AMD 67.3±8.4 47/33 rs11200638 0 0 <0.001 View
HTRA1 Control 68.2±7.8 46/39 rs11200638 0 0 <0.001 View
VEGFA Early AMD 73±13 235/104 rs1570360 0 0 1.86E-01 View
VEGFA wet AMD 77±10 270/149 rs1570360 0 0 1.86E-01 View
AMD 70.3±9.15 31/67 12592048
VEGFA Control 72±10 235/139 rs1570360 0 0 1.86E-01 View
LOC387715 AMD 74.4±8.1 rs10490924 2.21 1.47-.35 2.00E-04
LOC387715 Control 72.24±7.4 rs10490924 2.21 1.47-.35 2.00E-04
CCR2 Early AMD 76±12 214/265 rs1799865 0 0 7.23E-01 View
CCR2 Control 75±9 96/119 rs1799865 0 0 7.23E-01 View
BAIAP2L2 Control 70.57±9.58 297/275 rs760975 0 0 0.00E+00
BAIAP2L2 AMD 64.79±8.85 178/398 rs760975 0 0 0.00E+00
CFH wet AMD 71.3 73/38 rs1061170 3.15 1.24-.66 5.80E-03 View
CFH Control 69.8 37/21 rs1061170 3.15 1.24-.66 5.80E-03 View
CFH Control 72 222/133 rs800292 0.44 0.28-.69 4.00E-04 View
Control 68.9±11.78 25/85 26261643
CFH Early AMD 73 227/103 rs800292 0.44 0.28-.69 4.00E-04 View
CFH wet AMD 77 254/139 rs800292 0.44 0.28-.69 4.00E-04 View
TNF AMD 72.0±9.0 35/37 rs1800630 0 0 8.70E-02 View
TNF Control 62.8±8.9 69/55 rs1800630 0 0 8.70E-02 View
CFI AMD rs10033900 1.1 0.4-2.6 8.00E-01 View
HERPUD1 PCV 65.88±10.18 50/51 rs2217332 2.192 1.318-3.645 2.00E-03
HERPUD1 AMD 68.17±8.96 50/53 rs2217332 2.192 1.318-3.645 2.00E-03
HERPUD1 Control 58.61±8.43 76/116 rs2217332 2.192 1.318-3.645 2.00E-03
APOE wet AMD 70.94±7.87 16/69 rs429358 0.59 (0.21-.63) 4.24E-01 21541275 View
LIPC Control 77.0±4.6 116/105 0.79 (0.62-0.99) 4.50E-02 26261643 View
LIPC Dry AMD 78.1±4.2 463/351 0.79 (0.62-0.99) 4.50E-02 21447678 View
LIPC Drusen 78.9±4.9 548/401 0.79 (0.62-0.99) 4.50E-02 21447678 View
LIPC Geographic Atrophy 79.5±5.5 129/130 0.79 (0.62-0.99) 4.50E-02 21447678 View
LIPC wet AMD 80.7±5.1 447/350 0.79 (0.62-0.99) 4.50E-02 21447678 View
ABCR AMD 5 (1.6-0) 1.30E-03 21447678
AMD 63.6±10.4 10880298
AMD 68.9±9.0
CFH Advanced AMD 65.8±8.5 81/38 rs1061170 0 0 1.00E-03 View
CFH Control 66.2±6.9 58/41 rs1061170 0 0 1.00E-03 24498989 View
APOE Control 69.37±9.00 45/35 rs429358 0.59 (0.21-.63) 4.24E-01 15488782 View
CFH AMD 70.7±5.4 146/260 rs1061170 1.69 (1.2-.3) 2.00E-03 24498989 View
CFH Control 68.7±5.3 65/105 rs1061170 1.69 (1.2-.3) 2.00E-03 24970616 View
ABCA4 Control 75.1±5.8 156/126 rs3112831 1.47 (1.84-.15) 1.50E-03 24970616 View
ABCA4 AMD 76.74±5.82 190/163 rs3112831 1.47 (1.84-.15) 1.50E-03 21106043 View
TLR4 AMD 79.0±7.9 rs4986790 2.25 (1.43-.56) 1.00E-03 21106043 View
TLR4 Control 75.1±5.0 rs4986790 2.25 (1.43-.56) 1.00E-03 15829498 View
LIPC Control 80.2±4.4 597/386 rs493258 0.83 (0.58-1.18) 3.00E-01 15829498 View
LIPC Early AMD rs493258 0.83 (0.58-1.18) 3.00E-01 24223199 View
LIPC Advanced AMD rs493258 0.83 (0.58-1.18) 3.00E-01 24223199 View
CFH AMD 67±9.21 56/101 rs800292 0.45 (0.33-0.62) 9.01E-07 24223199 View
APOE AMD 79.4±58 67/42 rs7412 2.65 (1.05-.73) 4.00E-02 15488782 View
CFH Control 69±9.00 80/124 rs800292 0.45 (0.33-0.62) 9.01E-07 24608419 View
ABCR AMD 1.033 (0.814-.311) 9.12E-01 24608419
AMD 69.4±8.9 111/189 11726554
Control 65.1±9.5 159/141 24685762
AMD 72.18±7.9 1038/642 24685762
AMD 72.4±8.3 908/526 32553749
AMD 83.19±4.2 335/202 32553749
AMD 32553749
AMD 74.98±5.9 1515/1125 32553749
AMD 75.18±9.1 39/37 32553749
APOE AMD 46/31 rs7412 2.65 (1.05-.73) 4.00E-02 25077528 View
ABCA1 Advanced AMD rs1883025 0.77 (0.66-.90) 9.73E-04 32553749 View
ABCA1 Control rs1883025 0.77 (0.66-.90) 9.73E-04 20385826 View
ABCA4 AMD 73.5±9.7 112/53 0 0 3.40E-01 20385826 View
ABCA4 Control 66.7±8.5 38/21 0 0 3.40E-01 12824224 View
ABCA4 AMD 66.1±11.2 18/15 0 0 3.40E-01 12824224 View
FRK Advanced AMD rs1999930 0.87 0 1.10E-08 12824224 View
FRK Control rs1999930 0.87 0 1.10E-08 21665990 View
CFH AMD rs10737680 3.11 (2.76-3.51) 1.60E-16 21665990 View
CFH Control rs10737680 3.11 (2.76-3.51) 1.60E-16 20385819 View
CETP wet AMD rs2303790 1.69 0 3.66E-07 20385819 View
APOE AMD 29/19 rs7412 2.65 (1.05-.73) 4.00E-02 25077528 View
CETP Control rs2303790 1.69 0 3.66E-07 25629512 View
SYN3 Early AMD 70.3±6.63 122/94 rs5749482 0 0 2.00E-02 25629512 View
CFH Early AMD 41/23 rs551397 2.11 (1.41-.26) <0.001 25893111 View
CFH Advanced AMD 170/301 rs551397 2.11 (1.41-.26) <0.001 22618592 View
CFH Control 252/217 rs551397 2.11 (1.41-.26) <0.001 22618592 View
LIPC AMD 74.7±8.4 895/596 rs493258 1.14 (0.94-.38) 3.88E-01 22618592 View
LIPC Control 69±7.6 916/663 rs493258 1.14 (0.94-.38) 3.88E-01 26641553 View
Early AMD 61.02±14.02 170/81 26641553
wet AMD 64.52±6.17 136/70 28918250
Control 66.36±7.49 503/304 28918250
APOE AMD 83/53 rs7412 2.65 (1.05-.73) 4.00E-02 25077528 View
VEGFB AMD 78.5±7.7 106/87 rs12366035 216.92 (11.67-033.9) 3.00E-04 28918250 View
CETP AMD rs5882 2.02 (0.762-.351) 1.57E-01 32454495 View
CETP Geographic Atrophy 77.78±9.8 35/17 rs708272 0 0 7.39E-01 26854823 View
CETP Control 61.48±11.3 508/292 rs708272 0 0 7.39E-01 32666702 View
REST wet AMD 1.149 (0.833-1.564) 3.79E-01 32666702 View
REST Control 1.149 (0.833-1.564) 3.79E-01 28173125 View
AMD 65.1±3.1 142/147 28173125
Control 64.3±3.0 1605/1523 25205864
AMD 63.9±3.1 15/19 25205864
Control 64.0±3.1 370/212 25205864
APOE wet AMD 42/28 rs7412 2.65 (1.05-.73) 4.00E-02 25077528 View
AMD 72.4±4.6 200/151 25205864
Control 70.7±4.2 1151/767 25205864
AMD 72.4±4.4 25205864
Control 71.5±4.7 248/133 25205864
AMD 76.4±8.1 127/63 25205864
Control 71.2±7.5 362/302 25205864
AMD 70.2±7.5 25205864
Control 68.5±6.9 99/110 25205864
AMD 69.3±7.0 21/26 25205864
Control 67.2±6.3 119/151 25205864
APOE wet AMD 76±49 197/110 rs429358 0 0 1.97E-01 29851526 View
APOE Dry AMD 70/44 rs7412 2.65 (1.05-.73) 4.00E-02 25077528 View
AMD 69.3±5.3 25205864
Control 67.1±4.9 96/110 25205864
AMD 71.3±5.4 32/75 25205864
Control 69.0±5.6 446/417 25205864
AMD 69.3±8.8 84/146 rs12678919 0.8615 (0.5495,1.351) 5.15E-01 25205864
Control 67.2±9.6 115/106 rs12678919 0.8615 (0.5495,1.351) 5.15E-01 26624898
PCSK9 AMD 75.3±7.7 110/110 rs12067569 0 0 6.10E-01 26624898 View
PCSK9 Control 74.3±7.6 121/154 rs12067569 0 0 6.10E-01 28456421 View
C5 AMD rs10985126 0.97 (0.72-.31) 8.30E-01 28456421 View
ARMS2 AMD 77.1±8.1 43/86 rs10490924 2.76 (2.06-.66) 1.90E-02 31720301 View
APOE AMD 71.8±9.50 33/54 rs429358 0.3 (0.1-.8) 2.00E-03 25077528 View
ARMS2 Advanced AMD 78.6+7.5 494/399 rs10490924 3 (2.64-3.40) 2.70E-72 32962278 View
ARMS2 Control 1117/1082 rs10490924 3 (2.64-3.40) 2.70E-72 22694956 View
LIPC Advanced AMD 79.31±8.96 924/704 rs493258 0.84 (0.74,0.96) 1.21E-04 22694956 View
LIPC Control 72.57±8.71 539/338 rs493258 0.84 (0.74,0.96) 1.21E-04 23348725 View
CFH Geographic Atrophy rs1061170 0 0 8.60E-01 23348725 View
CFH wet AMD rs1061170 0 0 8.60E-01 26503844 View
CFH Advanced AMD rs1061170 0 0 8.60E-01 26503844 View
CFH Control rs1061170 0 0 8.60E-01 26503844 View
Geographic Atrophy 26503844
wet AMD 20888482
APOE Control 70.0±8.10 20/29 rs429358 0.3 (0.1-.8) 2.00E-03 11721184 View
Advanced AMD 20888482
Control 20888482
LIPC Early AMD 72±12IQR 206/94 rs10468017 0 0 4.00E-02 20888482 View
LIPC wet AMD 76±11 193/107 rs10468017 0 0 4.00E-02 30399423 View
LIPC Geographic Atrophy 78±11 35/17 rs10468017 0 0 4.00E-02 30399423 View
LIPC Control 53±0 530/299 rs10468017 0 0 4.00E-02 30399423 View
HTRA1 amd 68.7±4.9 1527/1195 rs2284665 2.06 0 8.10E-43 30399423 View
CFH AMD rs1061170 0 0 <.001 29346644 View
CFH AMD 275/221 rs1061170 0 0 1.90E-01 27099955 View
CFH AMD 276/222 rs1061170 0 0 1.90E-01 23481534 View
APOE Control 514/721 rs429358 0.3 (0.1-.8) 2.00E-03 11721184 View
CFH AMD 275/222 rs1061170 0 0 1.90E-01 23481534 View
CFH AMD 78±7.5 471/364 rs1061170 0.61 (0.38-0.97) 4.00E-02 23481534 View
ARMS2 AMD 8038 rs10490924 1.37 (1.21-.54) 4.20E-07 29801032 View
ARMS2 AMD 80.2 rs10490924 1.37 (1.21-.54) 4.20E-07 21122828 View
ARMS2 AMD 79.1 rs10490924 1.37 (1.21-.54) 4.20E-07 21122828 View
ARMS2 AMD 81.5 rs10490924 1.37 (1.21-.54) 4.20E-07 21122828 View
CFHR5 AMD 72.59±7.88 96/52 rs201247969 0 0 2.24E-02 21122828 View
CFHR5 Control 67.11±7.68 19/36 rs201247969 0 0 2.24E-02 34382031 View
CFHR5 AMD 76.46±7.96 155/85 rs201247969 0 0 2.24E-02 34382031 View
CFHR5 Control 68.62±4.97 35/18 rs201247969 0 0 2.24E-02 34382031 View
APOE AMD 71.8±9.6 rs429358 0 (0.29-.66) 5.20E-01 11721184 View
CFH Dry AMD 73 117/53 rs1061170 0.11-0.47 0 3.30E-03 34382031 View
CFH AMD 76 33/19 rs1061170 0.11-0.47 0 3.30E-03 31916060 View
CFH AMD 92.08±2.25 618/251 rs570618 0 0 2.00E-03 31916060 View
CFH AMD 68.4 84/113 rs1329428 1.649 (1.069-2.543) 2.30E-02 33320170 View
CFH Control 63.5±0.04 159/245 rs1329428 1.649 (1.069-2.543) 2.30E-02 30696427 View
ARMS2 Control 69.0±7.9 956/1673 rs10490924 1.32 (1.02-.72) 4.00E-02 30696427 View
ARMS2 Early AMD 72.1±8.0 226/379 rs10490924 1.32 (1.02-.72) 4.00E-02 27257685 View
ARMS2 Dry AMD 73.8±9.0 209/333 rs10490924 1.32 (1.02-.72) 4.00E-02 27257685 View
ARMS2 Advanced AMD 76.9±8.3 636/1059 rs10490924 1.32 (1.02-.72) 4.00E-02 27257685 View
ARMS2 AMD 79.8±6.0 23/20 rs10490924 1.48 (0.65-.40) 3.50E-01 27257685 View
APOE wet AMD rs429358 0 (0.29-.66) 5.20E-01 10859513 View
ARMS2 AMD 81.7±8.8 12267 rs10490924 1.48 (0.65-.40) 3.50E-01 28251353 View
ARMS2 Control 64.6±10.9 96/104 rs10490924 2.61 (1.28-.32) 6.00E-04 28251353 View
ARMS2 AMD 66±11 124/166 rs10490924 2.61 (1.28-.32) 6.00E-04 30895599 View
ARMS2 Dry AMD 66±11 82/93 rs10490924 2.61 (1.28-.32) 6.00E-04 30895599 View
ARMS2 wet AMD 66.21±11.77 52/73 rs10490924 2.61 (1.28-.32) 6.00E-04 30895599 View
CFH AMD 69.4±9.36 170/286 rs800292 0.63 (0.48-.82) 1.00E-03 30895599 View
CFH Control 64.4±8.53 684/1140 rs800292 0.63 (0.48-.82) 1.00E-03 28120909 View
CFH AMD 70.07±8.36 65/85 rs551397 1.601 (1.129-.270) 8.00E-03 28120909 View
CFH Control 72.99±5.90 69/76 rs551397 1.601 (1.129-.270) 8.00E-03 24865190 View
ARMS2 Advanced AMD 73.9±8.7 55/161 rs10490924 0 0 7.00E-03 24865190 View
APOE Control 69.7±8.9 rs429358 0 (0.29-.66) 5.20E-01 10859513 View
ARMS2 wet AMD 1.43±0.03 rs10490924 3.4 (2.3-.1) 7.60E-10 23111182 View
ARMS2 Control 1.26±0.04 rs10490924 3.4 (2.3-.1) 7.60E-10 30154790 View
CFH AMD 44/26 rs1048663,rs3766405,rs412852,rs11582939,rs1066420, 0 0 8.45E-01 30154790 View
CFH amd 5.73 (3.96-.28) <0.00000005 27362858 View
CFH Control 5.73 (3.96-.28) <0.00000005 23103884 View
CFH AMD 63.4±8.2 1208/927 rs1061170 1.8 (1.3-2.4) 0.00E+00 23103884 View
CFH AMD 69.5±6.4 70/25 rs1061170 1.8 (1.3-2.4) 0.00E+00 24332537 View
ARMS2 Control 64.68±4.13 398/271 rs10490924 2.23 (1.83-.73) 1.03E-13 24332537 View
ARMS2 Control 73.48±2.76 235/261 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 Control 82.58±2.42 38/49 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
Control 50.5 63/25 10859513
ARMS2 Control 92.96±2.26 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 AMD 65.06±3.77 135/180 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 AMD 74.72±2.87 284/319 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 AMD 83.25±2.61 191/210 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 AMD 92.66±2.55 98/16 rs10490924 2.23 (1.83-.73) 1.03E-13 24576882 View
ARMS2 AMD rs10490924 2.86 (2.38-.44) 2.80E-29 24576882 View
ARMS2 Control rs10490924 2.86 (2.38-.44) 2.80E-29 18511946 View
GSTM1 AMD 80.2±7.3 53/47 0 0 2.40E-01 18511946
GSTM1 Control 77.5±9.5 41/44 0 0 2.40E-01 25897651
VEGFA amd 67.3±7.9 130/143 0 0 3.30E-01 25897651 View
APOE Dry AMD 76.2±8.72 52/43 rs429358 1.02 (0.43-.40) 9.64E-01 18498549 View
VEGFA Control 67.6±8.5 105/152 0 0 3.30E-01 22355348 View
ARMS2 AMD 1.06 (0.86-.30) 5.70E-01 22355348 View
ARMS2 Control 1.06 (0.86-.30) 5.70E-01 27416785 View
ARMS2 amd 78.03±0.68 109/53 1.81 0 7.00E-02 27416785 View
ARMS2 Control 76.4±0.56 94/70 1.81 0 7.00E-02 23302509 View
LINCO1317 AMD rs6733379 1.77 (1.30-.40) 3.90E-03 23302509
LINCO1317 Control rs6733379 1.77 (1.30-.40) 3.90E-03 28703135
Control 78.1 28703135
AMD 78.4 23/21 28558370
AMD 77.6 28558370
APOE wet AMD 78.9±7.51 55/18 rs429358 1.02 (0.43-.40) 9.64E-01 31654486 View
AMD 77.6 28558370
ARMS2 AMD 75.5±7.9 182/99 rs10490924 1.6 (1.16-.22) 5.00E-03 28558370 View
ARMS2 Control 66.7±6.8 87/56 rs10490924 1.6 (1.16-.22) 5.00E-03 27258093 View
ARMS2 AMD 76.6±8.5 556/379 rs10490924 1.6 (1.16-.22) 5.00E-03 27258093 View
ARMS2 Control 71.3±6.7 503/397 rs10490924 1.6 (1.16-.22) 5.00E-03 27258093 View
CFH Control 68.20±10.13 197/198 rs800292 0.612 (0.4876-.7681) 2.14E-05 27258093 View
CFH PCV 67.35±7.34 50/61 rs800292 0.612 (0.4876-.7681) 2.14E-05 26171855 View
CFH AMD 72.56±8.10 68/86 rs800292 0.612 (0.4876-.7681) 2.14E-05 26171855 View
ARMS2 AMD 73.7±7.5 65/188 rs10490924 0.9 (0.5-.5) 6.40E-01 26171855 View
ARMS2 PCV 69.9±9.1 110/271 rs10490924 0.9 (0.5-.5) 6.40E-01 23706946 View
APOE Control 65±45 656/757 rs429358 0 0 1.97E-01 29851526 View
APOE AMD 78.0±7.99 154/74 rs429358 1.02 (0.43-.40) 9.64E-01 31654486 View
ARMS2 AMD 80.1±6.8 32/19 rs10490924 0.9 (0.5-.5) 6.40E-01 23706946 View
ARMS2 Control 72.9±8.7 116/111 rs10490924 0.9 (0.5-.5) 6.40E-01 23706946 View
CFH AMD rs800292 2.9 (1.96-.27) 7.66E-08 23706946 View
CFH Advanced AMD 81.12±2.44 rs1410996 1.34 (1.18-.52) <0.001 22065928 View
CFH Geographic Atrophy 80.25±6.28 rs1410996 1.34 (1.18-.52) <0.001 33369641 View
CFH wet AMD 79.25±2.75 rs1410996 1.34 (1.18-.52) <0.001 33369641 View
ARMS2 Dry AMD 73.3±9.2 7/34 rs10490924 0.53 (0.32-0.88) 1.00E-02 33369641 View
ARMS2 wet AMD 71.3±8.2 10/40 rs10490924 0.53 (0.32-0.88) 1.00E-02 21236409 View
ARMS2 Control 68.6±7.4 37/101 rs10490924 0.53 (0.32-0.88) 1.00E-02 21236409 View
ARMS2 AMD 75.7±7.8 19/20 rs10490923 1.59 (0.17-14.74) 6.70E-01 21236409 View
APOE Control 73.2±8.06 52/43 rs429358 1.02 (0.43-.40) 9.64E-01 31654486 View
ARMS2 Control rs10490923 1.59 (0.17-14.74) 6.70E-01 28128407 View
CFH AMD rs1061170 0 0 1.60E-02 28128407 View
ARMS2 AMD 535/284 rs10490924 2.13 (1.74-2.61) 1.89E-13 17591627 View
ARMS2 Control 189/131 rs10490924 2.13 (1.74-2.61) 1.89E-13 20182747 View
ADAMTS9-AS2 AMD 74.92±10.80 19/42 rs6795735 0.86 (0.55-.34) 5.07E-01 20182747
ADAMTS9-AS2 AMD 72.27±8.17 272/283 rs6795735 0.86 (0.55-.34) 5.07E-01 27552409
CFH AMD 77.6±8.4 rs1061170 9.05 0 1.00E-13 27552409 View
CFH Control 70.2±7.6 rs1061170 9.05 0 1.00E-13 25074767 View
CFH Advanced AMD 70.2±5.2 460/359 rs1061170 3.8 (3.1-4.7) <0.0001 25074767 View
CFH Early AMD 68.1±4.7 1201/917 rs1061170 3.8 (3.1-4.7) <0.0001 21959373 View
CFH AMD 69.4 45/69 rs1061170 0 0 3.80E-01 31654486 View
CFH AMD 75.7±8.3 77/86 rs1061170 7.2 (3.6-4.5) <0.0001 21959373 View
CFH Control 74.2±7.7 67/85 rs1061170 7.2 (3.6-4.5) <0.0001 23867343 View
SERPING1 AMD 70.59±9.35 rs2511989 0 0 4.00E-05 23867343 View
SERPING1 Control 77.85±8.83 rs2511989 0 0 4.00E-05 18842294 View
C2 AMD 75.59±8.60 125/330 rs547154 0.57 (0.35-.91) 1.80E-02 18842294 View
C2 Control 48.22±16.18 434/431 rs547154 0.57 (0.35-.91) 1.80E-02 22232432 View
C3 wet AMD 74±7.5 89/331 rs2250656 0.94 (0.71-.24) 6.60E-01 22232432 View
C3 Control 72±6 80/117 rs2250656 0.94 (0.71-.24) 6.60E-01 22174912 View
ARMS2 AMD 78.7±7.4 29/42 rs10490924 0 0 3.20E-02 22174912 View
ARMS2 PCV 72.9±7.9 22/47 rs10490924 0 0 3.20E-02 28266609 View
CFH Geographic Atrophy 69.4 45/69 rs1061170 0 0 3.80E-01 20381870 View
ARMS2 Control 71.6±6.4 134/112 rs10490924 4.06 (2.45-6.75) 1.67E-08 28266609 View
ARMS2 Control 71.3±5.9 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 Control 72.7±5.6 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 74.6±7.4 34/45 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 73.8±7.1 73/15 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 73.7±8.0 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 74.2±8.5 43/40 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 77.0±7.4 39/26 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
ARMS2 AMD 78.0±7.0 rs10490924 4.06 (2.45-6.75) 1.67E-08 26614632 View
APOE Geographic Atrophy 67.20±11.28 28/16 rs429358 0.777 (0.395-.647) 4.80E-01 26614632 View
CFH Control rs1061170 0 0 3.80E-01 20381870 View
APOE Geographic Atrophy 78.76±6.57 204/107 rs429358 0.777 (0.395-.647) 4.80E-01 27149696 View
ARMS2 AMD 69.5±11.3 69/90 rs10490924 10.76 (5.14-2.52) 3.70E-07 27149696 View
ARMS2 Control 72.9±7.9 57/83 rs10490924 10.76 (5.14-2.52) 3.70E-07 19491722 View
ARMS2 wet AMD 78.1±7.6 rs10490924 3.1 (2.2-.5) <0.0001 19491722 View
ARMS2 Control 70.8±8.2 rs10490924 3.1 (2.2-.5) <0.0001 19065273 View
ARMS2 AMD 74.17±7.64 rs10490924 2.7 (1.32-.48) 5.40E-03 19065273 View
ARMS2 Control 71.82 rs10490924 2.7 (1.32-.48) 5.40E-03 24372405 View
CFH Control 1002/897 rs1061170 0.93 (0.84-.03) 1.70E-01 24372405 View
CFH Early AMD 793/835 rs1061170 0.93 (0.84-.03) 1.70E-01 23060141 View
CFH Advanced AMD 21/21 rs1061170 0.93 (0.84-.03) 1.70E-01 23060141 View
CFH AMD 77.5±7.5 187/106 rs1061170 1.97 (1.32-.94) 9.00E-04 20381870 View
CFH AMD rs1061170 2.43 (1.55-.79) 2.30E-04 27879347 View
CFH Control 131/36 rs1061170 2.43 (1.55-.79) 2.30E-04 26255974 View
RAD51B Control 73.9±10.8 92/85 rs17105278 1.67 (1.26-.23) 7.30E-04 26255974 View
RAD51B AMD 78.8±8.3 136/113 rs17105278 1.67 (1.26-.23) 7.30E-04 24526414 View
RAD51B Control 71.7±8.3 27/19 rs17105278 1.67 (1.26-.23) 7.30E-04 24526414 View
RAD51B AMD 73.6±9.2 38/79 rs17105278 1.67 (1.26-.23) 7.30E-04 24526414 View
CFH Control 69.5±8.2 257/53 rs1061170 13.9 (5.3-6.7) 0.00E+00 24526414 View
CFH AMD 76.9±9.6 262/214 rs1061170 13.9 (5.3-6.7) 0.00E+00 20346514 View
SERPING1 Control 2332/2294 rs2509897 0 0 8.70E-01 20346514 View
CFH Control 67.8±8.3 58/42 rs1061170 1.97 (1.32-.94) 9.00E-04 18461138 View
SERPING1 AMD 109/183 rs2509897 0 0 8.70E-01 19169411 View
CFH AMD rs10801555 0 0 1.60E-01 19169411 View
CFH AMD rs1061170 2.1 (1.4-.1) <0.001 25786237 View
CFH AMD rs1061170 1.9 (1.2-.9) 0.00E+00 25655794 View
CFH AMD 82.16±0.86 39/18 rs1061170 1.2 0 4.50E-01 19169232 View
CFH AMD 79.60±0.82 63/30 rs1061170 1.2 0 4.50E-01 21878851 View
CFH AMD rs1061170 0 0 6.90E-01 21878851 View
PLEKHA1 AMD rs1045216 1.37 (0.85-.20) 2.00E-01 26490493 View
ARMS2 AMD 61.7±9.2 106/51 rs2736911 0.9 (0.53-1.5) 7.73E-01 21191724 View
ARMS2 Control 61.6±8.2 119/39 rs2736911 0.9 (0.53-1.5) 7.73E-01 23687431 View
CFH AMD 70.0±7.6 174/106 rs1061170 1.97 (1.32-.94) 9.00E-04 18461138 View
ARMS2 AMD 76±5 rs10490924 0 0 2.60E-01 23687431 View
ARMS2 AMD 76±6 rs10490924 0 0 2.60E-01 21541271 View
ARMS2 AMD 76±8 rs10490924 0 0 2.60E-01 21541271 View
ARMS2 Dry AMD 76.2±8.1 22/74 rs10490924 0.86 (0.47-.57) 6.30E-01 21541271 View
ARMS2 wet AMD 75.7±7.6 45/95 rs10490924 0.86 (0.47-.57) 6.30E-01 24897289 View
ARMS2 wet AMD 75.8±7.4 16/60 rs10490924 0.86 (0.47-.57) 6.30E-01 24897289 View
ARMS2 Dry AMD 76.8±8.9 12/32 rs10490924 0.86 (0.47-.57) 6.30E-01 24897289 View
CFH AMD 47.9±7.4 446/402 rs1061170 0 0 4.20E-01 24897289 View
CFH Control 45.8±8.0 3033/2903 rs1061170 0 0 4.20E-01 27502478 View
HTRA1 AMD 73.1±7.4 rs1049331 0 0 <.001 27502478 View
CFH Control 70.0±7.6 149/131 rs1061170 1.97 (1.32-.94) 9.00E-04 18461138 View
CFH AMD 74.79±8.372 63/37 rs1061170 4.4 (2.2-.1) 1.00E-03 21682878 View
CFH Control 80.24±4.5 74/41 rs1061170 4.4 (2.2-.1) 1.00E-03 19568762 View
CFH Control 120/84 rs1061170 5.82 (3.64-.32) <.001 19568762 View
CFH AMD 129/90 rs1061170 5.82 (3.64-.32) <.001 18423869 View
CFH AMD 132/85 rs1061170 5.82 (3.64-.32) <.001 18423869 View
CFH AMD 143/93 rs1061170 5.82 (3.64-.32) <.001 18423869 View
ARMS2 AMD 75.5±8.3 478/ rs10490923 0 0 1.16E-01 18423869 View
ARMS2 Control 66.8±8.3 218/ rs10490923 0 0 1.16E-01 19933179 View
ARMS2 AMD 82.4±7.2 121/75 rs3750846 0 0 1.00E-04 19933179 View
CFH Geographic Atrophy 76.3±5.4 181/112 rs1061170 0.88 (0.56-.41) 6.00E-01 32371126 View
APOE AMD 81±8 rs429358 0.43 (0.21-.88) 2.00E-03 18461138 View
CFH wet AMD 73.6±5.8 65/39 rs1061170 0.88 (0.56-.41) 6.00E-01 31899035 View
CFH Early AMD 62.1±8.1 222/184 rs1061170 0 0 4.00E-01 31899035 View
CFH Early AMD 62.3±7.5 541/370 rs1061170 0 0 4.00E-01 25838066 View
ARMS2 AMD 70.3±8.8 34/62 1.18 (0.78-.78) 4.25E-01 25838066 View
ARMS2 Control 67±9.5 53/43 1.18 (0.78-.78) 4.25E-01 23326481 View
ARMS2 AMD 75.9±7.5 282/174 rs10490924 2.09 (1.63-2.67) <0.0001 23326481 View
ARMS2 Control 66.4±8.1 128/106 rs10490924 2.09 (1.63-2.67) <0.0001 19255159 View
ARMS2 AMD 48.1±8.1 81/199 rs10490924 0 0 <0.0001 19255159 View
ARMS2 AMD 50.2±8.0 44/82 rs10490924 0 0 <0.0001 28002601 View
ARMS2 AMD 46.4±7.9 37/117 rs10490924 0 0 <0.0001 28002601 View
APOE Early AMD 71.14±9.20 35/64 rs429358 0 0 9.55E-01 29851526 View
APOE Control 69±9 rs429358 0.43 (0.21-.88) 2.00E-03 9634502 View
ARMS2 CNV 72.3±8.4 94/109 rs10490924 0 0 <0.0001 28002601 View
CFH Control 51.2±16.3 629/722 rs800292 1.691 (1.211-.363) 1.98E-03 28002601 View
CFH AMD 77.7±8.4 115/293 rs800292 1.691 (1.211-.363) 1.98E-03 31988359 View
CXCL8 AMD rs4073 0 0 1.20E-01 31988359 View
ARMS2 AMD rs10490924 1.86 0 3.31E-05 26154559 View
CFH AMD rs800292 0.596 (0.447-0.796) 1.00E-03 19933195 View
CFH AMD rs1061170 0 0 1.54E-06 23289807 View
ARMS2 AMD 73.6±7.9 78/178 rs10490924 0.501 (0.201-.338) 5.30E-04 20574013 View
ARMS2 AMD 74.5±7.7 71/135 rs10490924 0.501 (0.201-.338) 5.30E-04 28835685 View
ARMS2 Drusen 71.20±10.17 440/512 rs10490923 1.5 (1.19-1.89) 1.00E-03 28835685 View
AMD 61.34±7.39 44/65 9634502
ARMS2 Drusen 74.51±8.02 454/154 rs10490923 1.5 (1.19-1.89) 1.00E-03 33088170 View
CFH Early AMD 67.8 935/708 rs1061170 0.22 (0.15-.31) <0.0001 33088170 View
CFH Advanced AMD 69.9 256/166 rs1061170 0.22 (0.15-.31) <0.0001 27420564 View
CFH AMD 122/75 rs1061170 1.84 (1.23-.75) 3.00E-03 27420564 View
CFH Control 83/67 rs1061170 1.84 (1.23-.75) 3.00E-03 19797206 View
CFH Control 67±15 202/286 rs1061170 3.8 (2.04-.05) <0.001 19797206 View
CFH AMD 78±8 463/453 rs1061170 3.8 (2.04-.05) <0.001 22133792 View
ARMS2 AMD rs10490924 1.39 (0.93,2.07) 1.00E-01 22133792 View
CFH AMD rs1061170 1.53 (0.86,2.72) 1.63E-09 19202148 View
CFH AMD 75.0±5.6 1319/1097 rs1061170 1.65 (1.17-.34) 0.00E+00 19823576 View
AMD 65.5±7.14 26398858
CFH AMD 77.8±6.2 121/100 rs1061170 1.65 (1.17-.34) 0.00E+00 27768796 View
CFH AMD 82.1±6.2 98/39 rs1061170 1.65 (1.17-.34) 0.00E+00 27768796 View
ARMS2 AMD rs10490924 1.23 (1.06-.41) 2.00E-03 27768796 View
CFHR5 AMD 78±6.7 142/82 rs10922153 0 0 5.60E-01 23098369 View
ARMS2 AMD 72.2±8.2 151/348 rs10490924 1.63 (1.06-.50) 2.50E-02 23582991 View
ARMS2 AMD 72.1±8.2 66/197 rs10490924 1.63 (1.06-.50) 2.50E-02 26275133 View
ARMS2 AMD 71.6±8.6 40/89 rs10490924 1.63 (1.06-.50) 2.50E-02 26275133 View
CFH AMD 74.0±6.5 88/39 rs1061170 0.42 (0.23-0.83) 1.00E-02 26275133 View
CFH Control 73.0±6.9 72/51 rs1061170 0.42 (0.23-0.83) 1.00E-02 26132079 View
CFH AMD 53.9±0.1 5633/4662 rs1061170 0 0 8.80E-01 26132079 View
AMD 62.07±8.02 26398858
CFH AMD rs800292 0.432 (0.294-0.635) 1.91E-05 28332910 View
CFH AMD 68.8±8.6 49/95 rs800292 0 0 9.00E-03 26848857 View
CFH AMD 77.9±6.9 77/49 rs1061170 1.02 (0.67-1.56) 22594510 View
CFH AMD 77.4±7.9 157/98 rs1061170 1.02 (0.67-1.56) 24070809 View
CFH AMD 78.1±7.0 78/50 rs1061170 1.02 (0.67-1.56) 24070809 View
CFH AMD 77.7±7.5 312/197 rs1061170 1.02 (0.67-1.56) 24070809 View
CFHR5 AMD 60±9 1843/2230 rs10922153 0.84 (0.62-1.12) 2.50E-01 24070809 View
CFHR5 Control 64±9 136/164 rs10922153 0.84 2.50E-01 29453225 View
CTNNA3 wet AMD rs10997482 1.57 (1.25-1.97) 2.77E-05 29453225 View
CTNNA3 AMD 80.9±7.8 22/52 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CFH AMD 64.8 231/190 rs800292 1.16 (0.81-1.65) 2.50E-08 26398858 View
CTNNA3 AMD 81.6±6.3 52/269 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 wet AMD 81.1±7.4 45225 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 AMD 83.4±7.0 45132 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 wet AMD 71.6±5.9 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 AMD 76.4±8.4 171/375 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 AMD 77.6±7.9 67/190 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 wet AMD 76.8±8.3 230/573 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
CTNNA3 AMD 77.4±8.0 38/94 rs10997482 1.57 (1.25-1.97) 2.77E-05 28775256 View
HTRA1 Advanced AMD rs11200638 3.973 (2.928,5.390) 2.70E-17 28775256 View
HTRA1 Control rs11200638 3.973 (2.928,5.390) 2.70E-17 18682806 View
CFH Control 66.5 114/101 rs800292 1.16 (0.81-1.65) 2.50E-08 19259132 View
CFB wet AMD 230/173 rs12614 0.21 (0.04-1.05) 5.80E-02 18682806 View
CFH AMD 76.4±8.1 111/48 rs1061170 2 (1.2-.4) 1.00E-02 28926193 View
CFH Control 73.5±6.8 105/47 rs1061170 2 (1.2-.4) 1.00E-02 23112567 View
ARMS2 AMD rs10490924 0 0 5.30E-30 23112567 View
LOC387715/ARMS2 AMD 72.5±7.8 45/39 rs10664316 0.131 (0.032-.529) 3.00E-03 17884985
ARMS2 wet AMD 70.0±9.7 80/70 rs10490924 0 0 5.00E-04 19796758 View
ARMS2 Control 77.2±7.5 46/79 rs10490924 0 0 5.00E-04 32507953 View
CFH AMD rs3766405 0 0 9.50E-02 32507953 View
C3 AMD 82.1(6.7) 50/18 rs2230199 37 (10.7-28.1) 9.00E-04 23972322 View
C3 AMD 79.2(7.3) 729/398 rs2230199 37 (10.7-28.1) 9.00E-04 30681643 View
SYN3 AMD 75.86±8.16 316/246 rs9621532 1.41 (0.98-.03) 6.70E-02 19259132 View
C3 AMD 74.1(6.6) 292/108 rs2230199 37 (10.7-28.1) 9.00E-04 30681643 View
C3 Control 66.4(7.8) 278/163 rs2230199 37 (10.7-28.1) 9.00E-04 30681643 View
SCARB1 AMD 70.3±7.2 54/23 rs5888 2.9 (1.6-.3) <0.002 30681643 View
SCARB1 Control 77.9±9.8 45/16 rs5888 2.9 (1.6-.3) <0.002 19806217 View
SCARB1 AMD 74.8±5.6 194/144 rs5888 2.9 (1.6-.3) <0.002 19806217 View
SCARB1 Control 79.0±8.0 46/39 rs5888 2.9 (1.6-.3) <0.002 19806217 View
CFH AMD 76.4±8.2 17/41 rs800292 0 0 8.49E-01 19806217 View
CFH PCV 72.2±8.8 13/57 rs800292 0 0 8.49E-01 24961698 View
ARMS2 Dry AMD 73.3±9.2 7/34 rs10490924 0.53 (0.32-0.88) 1.00E-02 24961698 View
ARMS2 wet AMD 71.3±8.2 10/40 rs10490924 0.53 (0.32-0.88) 1.00E-02 21784201 View
SYN3 Control 72.72±6.63 745/456 rs9621532 1.41 (0.98-.03) 6.70E-02 21613373 View
ARMS2 PCV 70.3±9.2 12/48 rs10490924 0.53 (0.32-0.88) 1.00E-02 21784201 View
ARMS2 Control 68.6±7.4 37/101 rs10490924 0.53 (0.32-0.88) 1.00E-02 21784201 View
CFH Control 66.07±9.79 257/222 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 21784201 View
CFH AMD 73.05±9.12 266/218 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 34233521 View
CFH Early AMD 71.14±9.20 83/68 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 34233521 View
CFH Advanced AMD 74.16±9.13 185/148 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 34233521 View
CFH Dry AMD 72.75±9.55 107/96 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 34233521 View
CFH wet AMD 73.61±9.03 160/121 rs1410996 1.8198 (1.1727-.8383) 7.90E-03 34233521 View
CFHR5 wet AMD 70.40±0.21 259/244 rs10922153 0.53 (0.46-0.62) 1.11E-16 34233521 View
CFHR5 Geographic Atrophy 69.71±0.27 223/156 rs10922153 0.53 (0.46-0.62) 1.11E-16 23523162 View
TOMM40 AMD 76.8±6.6 510/284 rs10119 1.17 (0.74-1.87) 7.40E-01 21613373 View
ARMS2 wet AMD 75.9±7.4 74/82 NA 0 5.61E-01 23523162 View
ARMS2 PCV 67.5±9.0 49/111 NA 0 5.61E-01 22491416 View
ARMS2 Control 73.6±7.4 136/111 NA 0 5.61E-01 22491416 View
CFH AMD 78.3±7.5 45241 rs1061170 0 0 6.20E-01 22491416 View
CFH AMD 77.7±6.9 34/32 rs1061170 0 0 6.20E-01 28744656 View
CFH AMD 77.1±7.1 rs1061170 0 0 6.20E-01 28744656 View
CFH AMD 78.4±7.0 22/13 rs1061170 0 0 6.20E-01 28744656 View
CFH AMD 78.5±7.1 27/20 rs1061170 0 0 6.20E-01 28744656 View
CFH AMD 74.7±7.5 rs1061170 0 0 6.20E-01 28744656 View
CFH Control 75.4±7.2 77/34 rs88292 0.48 (0.34-0.67) <.001 28744656 View
TOMM40 Control 76.2±5.3 494/118 rs10119 1.17 (0.74-1.87) 7.40E-01 19384966 View
CFH AMD 78.5±7.2 91/63 rs88292 0.48 (0.34-0.67) <.001 24557084 View
CFH Geographic Atrophy 76.5±7.5 42/31 rs88292 0.48 (0.34-0.67) <.001 24557084 View
CFH AMD 75.9±6.4 50/27 rs3753394 0 0 2.80E-02 24557084 View
CFH Control 71.6±7.8 34/41 rs3753394 0 0 2.80E-02 22035603 View
PRKCB AMD rs1976194 0 0 0.436/0.615/0.435 22035603 View
ARMS2 AMD 3.25 (2.36-4.41) 2.70E-15 23577725 View
ARMS2 AMD 69.4±7.9 175/219 rs10490924 0 0 4.00E-03 19822855 View
CFH wet AMD 79.0±7.4 714/366 rs1061170 2.3 (1.7-.2) <0.0001 25558172 View
CFH Control 67.8±7.7 243/163 rs1061170 2.3 (1.7-.2) <0.0001 20664795 View
CFH AMD 65±8 rs1061170 5.5 (1.145-6.412) 2.81E-02 20664795 View
APOE Advanced AMD 74.16±9.13 126/109 rs429358 0 0 9.55E-01 33467888 View
APOE AMD 73.2±19.0 166/93 rs429358 0.91 (0.50-1.63) 3.70E-01 19384966 View
CFH Control 60±8 rs1061170 5.5 (1.145-6.412) 2.81E-02 23362846 View
CFH AMD 73.8±8.2 rs1061170 0 0 9.10E-01 23362846 View
CFH AMD 79.2±7.3 rs1061170 0 0 9.10E-01 22481475 View
CFH AMD 77.8±7.5 rs1061170 0 0 9.10E-01 22481475 View
HTRA1 AMD rs11200638 3.21 (1.88-.50) 1.16E-05 22481475 View
HTRA1 PCV rs11200638 3.21 (1.88-.50) 1.16E-05 27338780 View
HTRA1 Control rs11200638 3.21 (1.88-.50) 1.16E-05 27338780 View
LOXL1 Dry AMD 73.3±9.2 7/34 rs10490942 0 0 2.10E-01 27338780 View
LOXL1 wet AMD 71.3±8.2 10/40 rs10490942 0 0 2.10E-01 21855673 View
LOXL1 PCV 70.3±9.2 12/48 rs10490942 0 0 2.10E-01 21855673 View
APOE AMD 59.0±14.0 121/86 rs429358 0.91 (0.50-1.63) 3.70E-01 12742846 View
ARMS2/HTRA1 AMD rs10490923 0.68 (0.53-.87) 2.00E-03 21855673
CFH AMD 77.5±7.198 55/66 rs1410996 0 0 1.40E-02 23572227 View
CFH Control rs1410996 0 0 1.40E-02 23534868 View
C3 AMD 75.4 231/118 rs2230199 0.48 (0.16-0.93) 2.10E-02 23534868 View
CFH Control 65.1±9.5 159/142 rs800292 1.451 (1.145,1.840) 2.00E-03 23373431 View
CFH AMD 69.4±8.9 111/189 rs800292 1.451 (1.145,1.840) 2.00E-03 25771815 View
CFH PCV 66.8±9.7 112/188 rs800292 1.451 (1.145,1.840) 2.00E-03 25771815 View
CFBH9L PCV 73±8.2 23/32 rs4151667 0.62 (0.18-2.04) 1.10E-01 25771815
CFBH9L AMD rs4151667 0.62 (0.18-2.04) 1.10E-01 20378180
CFBH9L Control rs4151667 0.62 (0.18-2.04) 1.10E-01 20378180
APOE AMD 78.2±7.1 67/37 rs429358 0.91 (0.50-1.63) 3.70E-01 12742846 View
ARMS2 PCV 71.9±9.4 45050 rs10490924 0 0 3.40E-02 20378180 View
ARMS2 PCV 74.7±8.7 45153 rs10490924 0 0 3.40E-02 31376050 View
ARMS2 PCV 72.9±12.2 44941 rs10490924 0 0 3.40E-02 31376050 View
C3 Advanced AMD 77.6 271/166 rs2230199 1.55 (1.15-.08) 3.00E-03 31376050 View
C3 Control 74.9 268/168 rs2230199 1.55 (1.15-.08) 3.00E-03 20157618 View
ARMS2 Control 72.9±8.4 28/19 rs10490924 0 0 1.00E-02 20157618 View
ARMS2 Geographic Atrophy 80.1±7.9 34/23 rs10490924 0 0 1.00E-02 32138827 View
ARMS2 PCV 72.8±7.9 45276 rs10490924 0 0 1.00E-02 32138827 View
ARMS2 AMD 76.7±7.3 40/33 rs10490924 0 0 1.00E-02 32138827 View
RORA AMD rs12916023 0 0 5.00E-01 32138827 View
APOE Control 72.5±8.6 113/47 rs429358 0.91 (0.50-1.63) 3.70E-01 12742846 View
RORA Control rs12916023 0 0 5.00E-01 21060049 View
ARMS2 AMD rs10490924 3.26 (1.89e5.61) <0.05 21060049 View
RIMS3 AMD 79.6±4.98 111/284 rs11208590 0 0 9.60E-04 26681391 View
RIMS3 Control 77.6±4.8 97/101 rs11208590 0 0 9.60E-04 21197116 View
RIMS3 AMD 77.3±9.3 284/160 rs11208590 0 0 9.60E-04 21197116 View
RIMS3 Control 69.6±8.3 159/141 rs11208590 0 0 9.60E-04 21197116 View
CFH AMD 74±8.6 248/139 rs35292876 0.36 (0.25-.52) 8.30E-09 21197116 View
CFH AMD 71±7 173/95 rs35292876 0.36 (0.25-.52) 8.30E-09 22558131 View
CFH Control 76±7.7 182/145 rs35292876 0.36 (0.25-.52) 8.30E-09 22558131 View
ARMS2 PCV 73.1±8.2 75/175 rs10490924 0 0 1.70E-01 22558131 View
APOE Advanced AMD 77.6±6.82 184/68 rs429358 0 0 3.70E-02 12742846 View
ARMS2 AMD 76.9±7.7 37/95 rs10490924 0 0 1.70E-01 24595987 View
ARMS2 AMD rs10490924 3.14 (2.58-3.86) 1.97E-30 24595987 View
HTRA1 AMD rs2284665 2.37 (2.15-2.62) 3.18E-68 23592919 View
CFH AMD 76±8.0 191/91 rs1410996 0.55 (0.39-0.77) 3.20E-03 26337002 View
CFH Control 65.5±9.8 143/62 rs1410996 0.55 (0.39-0.77) 3.20E-03 24453474 View
CFH Control 72.4±8.8 101/104 rs800292 2.03 (1.39-.95) <0.001 24453474 View
CFH AMD 75.6±8.4 43/114 rs800292 2.03 (1.39-.95) <0.001 24865191 View
CFH PCV 73.1±8.2 80/253 rs800292 2.03 (1.39-.95) <0.001 24865191 View
CFHR5 Control 76.4±7.3 451/371 rs10922153 4.819 (3.64-.382) <0.0001 24865191 View
CFHR5 AMD 76.5±7.1 696/436 rs10922153 4.819 (3.64-.382) <0.0001 21807600 View
APOE Control 76.6±4.86 70/53 rs429358 0 0 3.70E-02 15111582 View
CFH AMD 77.9±7.5 33/65 rs800292 0 0 6.90E-01 21807600 View
CFH PCV 73.3±8.7 37/114 rs800292 0 0 6.90E-01 26918864 View
CFH Geographic Atrophy 82.3±10.1 rs800292 0 0 6.90E-01 26918864 View
CFH AMD 79.0±7.4 713/370 rs1061170 2 (1.5-2.6) <0.0001 26918864 View
CFH Control 67.9±7.6 119/177 rs1061170 2 (1.5-2.6) <0.0001 21621535 View
CFH AMD rs1061170 0 0 9.00E-03 21621535 View
ARMS2 AMD rs10490924 3.67 (3.33-4.05) 1.50E-138 22840423 View
CFH AMD rs1061170 2.7 0 4.80E-12 22705344 View
ARMS2 AMD rs10490924 1.52 (1.03-2.23) 0.00E+00 20861866 View
CFH Early AMD 72.9±4.6 77/105 rs800292 0 0 2.90E-02 22893087 View
CFH Early AMD 80.2 596/367 rs800292 0.45 (0.33-0.62) 9.01E-07 15111582 View
CFH Advanced AMD 78.3±3.2 rs800292 0 0 2.90E-02 25788651 View
CFH Control 73.1±4.8 114/181 rs800292 0 0 2.90E-02 25788651 View
CFH AMD 77.5±7.198 45/56 rs1410996 2.65 (1.030-.381) 3.80E-02 25788651 View
CFH Control 70.51±6.386 52/39 rs1410996 2.65 (1.030-.381) 3.80E-02 23414945 View
HTRA1 AMD 73.75±7.7 rs11200638 2.89 (1.93-.36) 0.00E+00 23414945 View
HTRA1 Control 73.6±8.72 rs11200638 2.89 (1.93-.36) 0.00E+00 31970928 View
POLR1C wet AMD 80 68/33 rs833060 1.39 (0.58-3.31) 4.60E-01 31970928 View
CFB Control 79±4.4 30/30 rs641153 0.2 (0.03-0.6) 3.00E-02 24143065 View
CFB Geographic Atrophy 30/28 rs641153 0.2 (0.03-0.6) 3.00E-02 19661236 View
CFB wet AMD 30/32 rs641153 0.2 (0.03-0.6) 3.00E-02 19661236 View
CFH Advanced AMD rs800292 0.45 (0.33-0.62) 9.01E-07 24608419 View
CFB Advanced AMD 82±6.9 60/60 rs641153 0.2 (0.03-0.6) 3.00E-02 19661236 View
CFH wet AMD 79.1±7.9 117/70 rs1410996 0.32 (0.21-0.49) <0.001 19661236 View
CFH Control 71.1±6.6 117/79 rs1410996 0.32 (0.21-0.49) <0.001 33765843 View
CFH Control 317/228 rs1061170 1.43 (1.14-1.79) 2.00E-03 33765843 View
CFH AMD 327/249 rs1061170 1.43 (1.14-1.79) 2.00E-03 27471039 View
CFH AMD 354/245 rs1061170 1.43 (1.14-1.79) 2.00E-03 27471039 View
CFH AMD 338/259 rs1061170 1.43 (1.14-1.79) 2.00E-03 27471039 View
KCNT2 AMD 77.4±12.7 2987/1794 rs187328863 2.12 (1.63-2.74) 1.29E-08 27471039 View
KCNT2 Control 72.8±11.6 945/642 rs187328863 2.12 (1.63-2.74) 1.29E-08 34563268 View
RORA AMD rs12916023 0 0 8.74E-02 34563268 View
CFH Control rs800292 0.45 (0.33-0.62) 9.01E-07 24608419 View
ARMS2/LOC387715 Control 120/84 rs10490924 2.83 (1.96-.09) <0.0001 19786043
ARMS2/LOC387715 AMD 129/90 rs10490924 2.83 (1.96-.09) <0.0001 18855541
ARMS2/LOC387715 AMD 141/76 rs10490924 2.83 (1.96-.09) <0.0001 18855541
ARMS2/LOC387715 AMD 132/104 rs10490924 2.83 (1.96-.09) <0.0001 18855541
ARMS2 AMD 76.6±8 33/28 rs10490924 0 0 4.60E-01 18855541 View
ARMS2 AMD 8.2±4.4 rs10490924 0 0 4.60E-01 31942429 View
ARMS2 AMD 6.8±3.4 rs10490924 0 0 4.60E-01 31942429 View
ARMS2 AMD 8.3±3.2 rs10490924 0 0 4.60E-01 31942429 View
ARMS2 AMD 9.1±3.4 rs10490924 0 0 4.60E-01 31942429 View
CFH wet AMD 74.56±8.83 27/73 rs800292 2.08 (1.43-.04) 1.20E-04 31942429 View
AMD 72±9.3 67/67 24608419
CFH PCV 72.71±8.25 81/19 rs800292 2.08 (1.43-.04) 1.20E-04 20157352 View
CFH Control 72.22±8.51 104/86 rs800292 2.08 (1.43-.04) 1.20E-04 20157352 View
ARMS2 AMD 66.3±8.8 58/46 rs10490924 3.13 (2.08-.71) <0.001 20157352 View
ARMS2 Control 67.9±7.7 55/45 rs10490924 3.13 (2.08-.71) <0.001 33737801 View
ARMS2 wet AMD 54/66 rs10490924 2.08 (1.16-.72) 3.10E-03 33737801 View
ARMS2 Control 59/44 rs10490924 2.08 (1.16-.72) 3.10E-03 28794612 View
SGCD AMD 171/97 rs970476 0 0 6.01E-01 28794612 View
CFH wet AMD 77 527/449 rs1061170 2.3 (2.0-.6) 1.05E-34 30257524 View
CFH Control 72 560/440 rs1061170 2.3 (2.0-.6) 1.05E-34 29487693 View
CFH pcv 62.9±8.9 rs1061170 3.081 (1.493-.360) 2.30E-03 29487693 View
APOE Dry AMD 72.75±9.55 74/60 rs429358 0 0 9.55E-01 33467888 View
Control 59±7.2 71/93 25945528
CFH Control 62.2±7.6 rs1061170 3.081 (1.493-.360) 2.30E-03 22536038 View
ARMS2 Advanced AMD 9484/7697 rs10490924 2.76 (2.72-.80) 4E-540 22536038 View
ARMS2 Control 27814/32260 rs10490924 2.76 (2.72-.80) 4E-540 23455636 View
ESR1Haplotype1(T-A) AMD 581/427 rs2234693/rs9340799 1.07 (0.86-.33) 1.60E-01 23455636
ESR1Haplotype1(T-A) AMD 1322/963 rs2234693/rs9340799 1.07 (0.86-.33) 1.60E-01 17325140
ESR1Haplotype1(T-A) AMD 739/539 rs2234693/rs9340799 1.07 (0.86-.33) 1.60E-01 17325140
VEGFA AMD 71.7±5.3 37/40 rs1413711 0.47 (0.24-0.91) 17325140 View
VEGFA Control 62.8±5.2 45/40 rs1413711 0.47 (0.24-0.91) 25349791 View
CFH AMD rs10922109 0.38 0 9.60E-618 25349791 View
HTRA1 wet AMD 76.62±8.4 58/42 rs11200638 0 0 4.84E-01 26691988 View
CFH Early AMD 62.4±10.2 rs1061170 11.52 (5.05-6.28) 1.19E-07 25945528 View
LOXL1 Control 59 247/ rs1048661 2.80E-02 27672596 View
LOXL1 AMD 59 286/ rs1048661 2.80E-02 32793663 View
TNF Control 72.42±7.45 36/37 rs1799964 0 0 9.40E-01 32793663 View
TNF Geographic Atrophy 75.88±7.20 25/25 rs1799964 0 0 9.40E-01 26425318 View
TNF AMD 64.2±1.2 20/102 rs361525 0.98 (0.03-36.4) 1.00E+00 26425318 View
TNF Control 60±1.4 18/100 rs361525 0.98 (0.03-36.4) 1.00E+00 30662836 View
NFATC1 AMD 77.6±7.9 548/1207 0 0 1.50E-01 30662836
NFATC1 Control 70.9±7.8 278/686 0 0 1.50E-01 25015356
STH Control 72±7 33/42 rs62063857 1.51 (0.82-2.79) 1.20E-01 25015356 View
STH AMD 75±7 57/93 rs62063857 1.51 (0.82-2.79) 1.20E-01 32615840 View
CFH Advanced AMD 69.2±7.7 rs1061170 11.52 (5.05-6.28) 1.19E-07 16936080 View
STH wet AMD 75±7 48/86 rs62063857 1.51 (0.82-2.79) 1.20E-01 32615840 View
STH Dry AMD 76±8 rs62063857 1.51 (0.82-2.79) 1.20E-01 32615840 View
MERTK AMD NA 0 3.20E-01 32615840
HTRA1 AMD 67.0±10.3 36/46 rs11200638 0 0 <0.05 29299721 View
HTRA1 Control 61.8±10.2 37/52 rs11200638 0 0 <0.05 33387109 View
HTRA1 AMD 74.23±8.166 120/84 rs11200638 5.293 (2.904-9.934) 1.00E-07 33387109 View
HTRA1 Control 71.17±7.531 79/87 rs11200638 5.293 (2.904-9.934) 1.00E-07 28846052 View
CFH AMD 279/139 rs800292 1.349 (0.903-2.015) 1.43E-01 28846052 View
CFH AMD 75.1±8.3 79/43 rs1329428 0 0 4.20E-01 33279454 View
CFH Control 73.1±8.0 151/98 rs1329428 0 0 4.20E-01 32838591 View
CFH Control 63.9±6.6 rs1061170 11.52 (5.05-6.28) 1.19E-07 16936080 View
MCP-1 AMD 70.89±8.96 66/63 rs1024611 2.038 (0.893-.654) 8.70E-02 32838591
MCP-1 Control 69.24±8.40 61/70 rs1024611 2.038 (0.893-.654) 8.70E-02 32485729
CFH AMD 67.23±10.61 63/53 rs1061170 2.3 (1.2-.5) 32485729 View
CFH Control 60.05±6.58 53/47 rs1061170 2.3 (1.2-.5) 30285522 View
CFH AMD 73.8±7.7 184/112 rs2274700 0 0 1.86E-09 30285522 View
CFH Control 72.9±5.8 75/25 rs2274700 0 0 1.86E-09 33354892 View
CYP2C19 AMD 68.83 108/42 rs4244285 0 0 1.14E-01 33354892 View
CYP2C19 Control 68.22 220/76 rs4244285 0 0 1.14E-01 28095090 View
CFH AMD 64.97±7.1 40/75 rs1061170 12.65 (5.05-1.69) 1.00E-04 28095090 View
CFH Control 60.38±13.2 21/40 rs1061170 12.65 (5.05-1.69) 1.00E-04 23922956 View
TOMM40 AMD 69.4±8.9 111/189 rs2075650 0.979 (0.654-1.466) 9.18E-01 16936080 View
CFI AMD 71.9±8.5 95/313 rs10033900 8.47 (1.04-69.00) 0.00E+00 23922956 View
CFI AMD 72.5±8.9 rs10033900 8.47 (1.04-69.00) 0.00E+00 25352734 View
CFI Control 68.4±9.8 160/31 rs10033900 8.47 (1.04-69.00) 0.00E+00 25352734 View
CFH AMD 65.76±8.26 63/75 rs800292 0.525 (0.389-.709) 2.30E-05 25352734 View
CFH Control 65.16±8.32 68/78 rs800292 0.525 (0.389-.709) 2.30E-05 20132989 View
TLR4 AMD rs1927914 0.965 (0.582-.600) 8.90E-01 20132989 View
CFP AMD 75.1±7.9 339/283 rs909523 1.1 (0.8-.4) 7.30E-01 31083239 View
CFP Control 79.4±7.1 213/146 rs909523 1.1 (0.8-.4) 7.30E-01 22024702 View
HTRA1 wet AMD 0.226 (0.101-.505) 8.33E-05 22024702 View
HTRA1 Control 0.226 (0.101-.505) 8.33E-05 27841854 View
TOMM40 Control 65.1±9.5 158/142 rs2075650 0.979 (0.654-1.466) 9.18E-01 24146538 View
IL1RL1 Early AMD 74 188/82 rs1041973 1.423 (1.001-2.002) 5.00E-02 27841854 View
IL1RL1 wet AMD 77 188/105 rs1041973 1.423 (1.001-2.002) 5.00E-02 32871771 View
IL1RL1 Geographic Atrophy 70 39/14 rs1041973 1.423 (1.001-2.002) 5.00E-02 32871771 View
IL1RL1 Control 83 182/99 rs1041973 1.423 (1.001-2.002) 5.00E-02 32871771 View
CFH AMD 67.35±6.57 42/88 1.98 (0.17-2.17) 5.70E-01 32871771 View
CFH Control 65.92±8.32 25/95 1.98 (0.17-2.17) 5.70E-01 29132549 View
ELN AMD 57-91 17/61 rs868005 0 0 5.40E-01 29132549 View
ELN PCV 57-86 20/83 rs868005 0 0 5.40E-01 18326737 View
ELN Control 59-83 35/69 rs868005 0 0 5.40E-01 18326737 View
wet AMD 68.2±6.3 18326737
NOS3 wet AMD 77.0±7.3 41/34 rs2070744 0 0 9.08E-01 24146538 View
Control 70.0±7.8 27404493
CFH AMD 73.2±7.8 875/721 rs3753396 0 0 1.09E-15 27404493 View
CX3CR1 AMD 66.17±10.08 47/55 rs3732378 2.182 (0.875-5.445) 8.80E-02 29398083 View
CX3CR1 Control 68.93±10.59 54/61 rs3732378 2.182 (0.875-5.445) 8.80E-02 26464724 View
MT1A Control 73.3±8.03 55/43 rs11076161 1.03 (0.88-.20) 5.93E-01 26464724 View
MT1A AMD 77.7±7.84 79/51 rs11076161 1.03 (0.88-.20) 5.93E-01 28635422 View
MT1A Dry AMD 77.0±9.20 28/18 rs11076161 1.03 (0.88-.20) 5.93E-01 28635422 View
MT1A wet AMD 77.3±6.55 45254 rs11076161 1.03 (0.88-.20) 5.93E-01 28635422 View
MT1A Advanced AMD 78.7±7.33 27/22 rs11076161 1.03 (0.88-.20) 5.93E-01 28635422 View
ELN Control 74.2±8.4 194/142 rs2301995 1.38 (1.12-.71) 2.80E-03 28635422 View
NOS3 Control 76.5±6.5 37/38 rs2070744 0 0 9.08E-01 19860767 View
ELN AMD 77.7±8.4 115/293 rs2301995 1.38 (1.12-.71) 2.80E-03 22003121 View
ELN PCV 75.1±8.5 137/381 rs2301995 1.38 (1.12-.71) 2.80E-03 22003121 View
ELN Control 68.4±9.8 68/74 rs2301995 1.38 (1.12-.71) 2.80E-03 22003121 View
ELN AMD 72.7±8.7 58/158 rs2301995 1.38 (1.12-.71) 2.80E-03 22003121 View
ELN PCV 71.8±7.8 32/122 rs2301995 1.38 (1.12-.71) 2.80E-03 22003121 View
TLR2 AMD 75±8 104/79 rs5743708 3.88 (1.76-.75) 3.00E-04 22003121 View
TLR2 Control 73±10 145/55 rs5743708 3.88 (1.76-.75) 3.00E-04 26398587 View
ARMS2 AMD 78.56±7.34 2910/2260 rs10490924 1.85 0 5.10E-116 26398587 View
ARMS2 Dry AMD 78.61±7.29 613/447 rs10490924 1.85 0 5.10E-116 26176866 View
ARMS2 CNV 79.54±6.93 717/522 rs10490924 1.85 0 5.10E-116 26176866 View
APOE Control 76/57 rs429358 0.51 (0.32-0.79) 9.00E-03 19860767 View
ARMS2 Control 72.24±7.14 11263/13867 rs10490924 1.85 0 5.10E-116 26176866 View
VEGFA AMD rs699947 1.02 (0.66-1.57) 2.50E-02 26176866 View
SLCO1B1 wet AMD 76.12±7.63 135/71 rs4149056 1.863 (1.290-.689) 1.00E-03 20019880 View
SLCO1B1 Control 53.12±22.06 217/84 rs4149056 1.863 (1.290-.689) 1.00E-03 30010042 View
TLR1 Geographic Atrophy 70±10 36/20 rs4833095 0 0 1.80E-01 30010042 View
TLR1 Control 79±10 51/22 rs4833095 0 0 1.80E-01 18385087 View
POLR1C AMD rs943080 1.13 (0.84-.51) 4.20E-01 18385087 View
DCDC1 AMD rs273609 0 0 3.72E-01 27064391 View
GSTM1 wet AMD 69.5±8.9 44/68 0.96 (0.55-.65) 8.89E-01 33565341
GSTM1 Control 63.2±9.4 0.96 (0.55-.65) 8.89E-01 21701824
APOE Control 32/62 rs429358 0.51 (0.32-0.79) 9.00E-03 16823865 View
CFH Control 73.3±8.03 53/43 rs3753394 1 (0.84-.19) 0.00E+00 21701824 View
CFH AMD 77.7±7.84 79/51 rs3753394 1 (0.84-.19) 0.00E+00 26152901 View
CFH Dry AMD 77.0±9.20 28/18 rs3753394 1 (0.84-.19) 0.00E+00 26152901 View
CFH wet AMD 77.3±6.55 45254 rs3753394 1 (0.84-.19) 0.00E+00 26152901 View
ERCC6 AMD rs3793784 0.89 (0.6521.22) 0.00E+00 26152901 View
NOS3 AMD 67±9.21 56/101 rs1799983 0.5785 (0.3644-.9184) 1.93E-02 21072178 View
NOS3 PCV 65±8.60 84/166 rs1799983 0.5785 (0.3644-.9184) 1.93E-02 26914548 View
NOS3 Control 69±9.00 80/124 rs1799983 0.5785 (0.3644-.9184) 1.93E-02 26914548 View
CFH AMD 73.09±7.69 40/87 rs1061170 3.32 (1.41-7.79) 0.00E+00 26914548 View
CFH Geographic Atrophy 71.33±10.74 rs1061170 3.32 (1.41-7.79) 0.00E+00 23306536 View
APOE wet AMD 73.61±9.03 116/84 rs429358 0 0 9.55E-01 33467888 View
APOE AMD 66/54 rs429358 0.51 (0.32-0.79) 9.00E-03 16823865 View
CFH wet AMD 73.36±7.53 32/73 rs1061170 3.32 (1.41-7.79) 0.00E+00 23306536 View
CFH AMD 72.4±5.32 rs1061170 3.32 (1.41-7.79) 0.00E+00 23306536 View
CFH Control 67.7±7.8 345/214 rs1061170 0 0 <0.0001 23306536 View
CFH AMD 78.8±7.4 508/616 rs1061170 0 0 <0.0001 23734082 View
ARMS2/LOC387715 AMD 67.71±9.29 54/83 rs10490924 1.98 (1.44-.71) 1.00E-04 23734082
ARMS2/LOC387715 Control 66.83±7.80 93/94 rs10490924 1.98 (1.44-.71) 1.00E-04 20456446
HTRA1 Control 57.9±11.6 159/239 rs11200638 0 0 <0.001 20456446 View
HTRA1 AMD 73.1±8.0 56/142 rs11200638 0 0 <0.001 22190594 View
HTRA1 PCV 70.2±6.7 16/79 rs11200638 0 0 <0.001 22190594 View
CFI Control 72±6 65/86 rs141853578 1.33 (0.86-2.04) 1.97E-01 22190594 View
APOE AMD 20/20 rs429358 0.51 (0.32-0.79) 9.00E-03 16823865 View
CFI AMD 75±8 81/139 rs141853578 1.33 (0.86-2.04) 1.97E-01 29392637 View
CFI wet AMD 75±8 71/132 rs141853578 1.33 (0.86-2.04) 1.97E-01 29392637 View
CFI Dry AMD 76±8 rs141853578 1.33 (0.86-2.04) 1.97E-01 29392637 View
PON1 AMD 79.41±6.97 201/104 rs705379 1.36 (1.08-.73) 9.90E-03 29392637 View
NOS2 Control 66.9±8.3 126/160 rs2255929 0.82 (0.65,1.04) 9.90E-02 22956172 View
AMD 76.4±7.6 257/455 20374233
MMP2 AMD 75±7.2 25/91 rs243865 0.609 (0.346-.070) 8.30E-02 View
MMP2 PCV 73±6.9 32/108 rs243865 0.609 (0.346-.070) 8.30E-02 29381911 View
MMP2 Control 72±5.8 75/114 rs243865 0.609 (0.346-.070) 8.30E-02 29381911 View
SLC11A2 AMD rs224589 0.99 (0.66-.48) 0.00E+00 29381911 View
ARMS2 AMD 69.3±10.40 140/70 rs10490924 2.94 (2.35-.67) 2.00E-21 16823865 View
SOD2 AMD rs4880 0.73 (0.45-.18) 1.90E-01 22371024 View
SCARB1 AMD 73.4±6.9 128/87 rs5888 1.054 (0.710-.564) 7.94E-01 19753309 View
SCARB1 Control 73.1±7.7 144/94 rs5888 1.054 (0.710-.564) 7.94E-01 27428740 View
ICOS AMD 66.7±8.2 98/125 rs10932037 1.11 (0.52-.35) 7.88E-01 27428740 View
ICOS Control 68.3±7.6 116/146 rs10932037 1.11 (0.52-.35) 7.88E-01 24083358 View
C2 AMD 67.53±8.94 61/92 rs547154 0.96 (0.50-1.85) 4.27E-01 24083358 View
C2 Control 61.94±8.06 98/99 rs547154 0.96 (0.50-1.85) 4.27E-01 22273503 View
C3 AMD 73.14±8.06 46/99 rs2230199 2.41 (1.90-.05) 7.00E-04 22273503 View
CFH AMD 64.97±7.1 40/75 rs1061170 0 0 5.00E-05 28470643 View
CFH Control 60.38±13.2 21/40 rs1061170 0 0 5.00E-05 18211923 View
ARMS2 AMD 73.1±6.25 330/210 rs10490924 2.94 (2.35-.67) 2.00E-21 22933840 View
CCR3 AMD 67.0±7.6 2456/1772 rs3091250 6.18 (2.25-6.93) 1.00E-04 18211923 View
VEGFA AMD 78.60±7.31 2826/2015 rs699947 0.99 (0.78-.26) 0.00E+00 23566847 View
VEGFA Control 71.58±7.22 10384/13406 rs699947 0.99 (0.78-.26) 0.00E+00 18708255 View
HLA-DQB1 AMD rs9274390 1.2 (1.14-.28) 1.40E-11 18708255 View
SERPING1 AMD 65.8±8.5 81/38 rs2511989 0 0 9.32E-01 26733291 View
SERPING1 Control 66.2±6.9 58/41 rs2511989 0 0 9.32E-01 21526158 View
CFH AMD rs1061170 2.81 (1.23-.42) 1.40E-02 21526158 View
SMUG1 Control 73±7 99/122 rs3087404 0.82 (0.54-1.25) 3.60E-01 23868022 View
SMUG1 AMD 76±8 108/171 rs3087404 0.82 (0.54-1.25) 3.60E-01 28095127 View
SMUG1 wet AMD 75±8 71/132 rs3087404 0.82 (0.54-1.25) 3.60E-01 28095127 View
ARMS2 Control 76.7±7.42 311/242 rs10490924 2.94 (2.35-.67) 2.00E-21 22933840 View
SMUG1 Dry AMD 81±7 37/39 rs3087404 0.82 (0.54-1.25) 3.60E-01 28095127 View
ADPRT1 wet AMD 76.6 58/36 0 0 1.50E-01 28095127
ADPRT1 Control 78.8 59/36 0 0 1.50E-01 15774926
FLT1 AMD 69.69±8.66 206/226 rs2281827 1.149 (0.952-.387) 1.48E-01 15774926 View
FLT1 Control 72.21±7.35 475/431 rs2281827 1.149 (0.952-.387) 1.48E-01 26914796 View
C3 Control 75.3±7.8 199/151 rs2250656 0 0 1.20E-01 26914796 View
C3 AMD 79.4±7.2 333/270 rs2250656 0 0 1.20E-01 17634448 View
CFH AMD 66.56±7.6 45/88 rs1061170 1.07 (0.93-1.23) 1.00E-04 17634448 View
CFH Control 54.24±7.01 23/57 rs1061170 1.07 (0.93-1.23) 1.00E-04 22936692 View
CCL2 CNV 64±6.6 49/41 rs4586 1.509 (0.667-.413) 3.24E-01 22936692 View
CFH AMD 74.2±10.0 rs1061170 9.3 (2.4-5.8) 1.00E-03 22933840 View
CCL2 Drusen 68±7.1 41/33 rs4586 1.509 (0.667-.413) 3.24E-01 23185481 View
CCL2 Control 64±5.9 58/48 rs4586 1.509 (0.667-.413) 3.24E-01 23185481 View
HTRA1 AMD rs11200638 5.04 (1.43-17.79) 5.00E-12 23185481 View
ACE AMD 73.90±7.98 44/35 0 0 2.18E-01 17904186
ACE Control 72.22±5.85 30/38 0 0 2.18E-01 21417676
ADIPOR12 AMD rs11061935 1.082 (0.6563-1.784) 8.02E-01 21417676
CFD AMD rs3826945 1.11 (1.01-.23) 3.20E-02 22387454 View
CFH AMD 78±6.6 rs1061170 2.31 (1.86-.85) 1.50E-04 22003108 View
CFH Control 77.2±6.7 rs1061170 2.31 (1.86-.85) 1.50E-04 20843825 View
ABCG1 AMD 75.3±7.6 106/129 rs57137919 1.03 (0.79-.34) 8.00E-01 20843825 View
CFH Control 78.1±6.3 rs1061170 9.3 (2.4-5.8) 1.00E-03 19845562 View
ABCG1 PCV 68.5±9.0 73/163 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 Control 74.4±7.7 211/154 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 AMD 67.3±10.1 58/131 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 PCV 63.1±10.5 53/134 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 Control 73.8±6.8 384/286 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 AMD 74.3±7.3 63/129 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 PCV 72.2±8.0 47/157 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
ABCG1 Control 47.9±15.1 105/52 rs57137919 1.03 (0.79-.34) 8.00E-01 27787563 View
CFH AMD 69.36±10.15 77/88 rs800292 1.53 (1.12-2.08) 6.90E-03 27787563 View
CFH Control 64.45±8.01 96/120 rs800292 1.53 (1.12-2.08) 6.90E-03 23233260 View
C3 Dry AMD 75.4±11.5 34/33 rs2230199 4.93 (1.98-2.25) 6.00E-04 19845562 View
MBL2 AMD 76.2&&8.7 68/41 rs1800451 1.75 (0.51-.98) 3.70E-01 23233260 View
MBL2 Control 75.0&&8.1 68/41 rs1800451 1.75 (0.51-.98) 3.70E-01 26207622 View
C3 Control 72.7±6.8 105/123 rs2230199 1.69 (1.15-.49) 8.10E-03 26207622 View
C3 AMD 76.4±7.6 99/167 rs2230199 1.69 (1.15-.49) 8.10E-03 27029644 View
C3 wet AMD 74.9±7.4 66/121 rs2230199 1.69 (1.15-.49) 8.10E-03 27029644 View
C3 Geographic Atrophy 80.6±6.6 33/46 rs2230199 1.69 (1.15-.49) 8.10E-03 27029644 View
KDR AMD 64.97±7.1 40/75 rs1531289 2.13 (1.011-4.489) 4.70E-02 27029644 View
KDR Control 60.38±13.2 21/40 rs1531289 2.13 (1.011-4.489) 4.70E-02 23030506 View
CFH AMD 73.4±8.3 28/67 rs1061170 1.78 (0.87-.68) 1.10E-01 23030506 View
CFH Control 73.6±8.5 30/69 rs1061170 1.78 (0.87-.68) 1.10E-01 17194541 View
C3 wet AMD 76.0±7.3 125/88 rs2230199 4.93 (1.98-2.25) 6.00E-04 23209669 View
CFH AMD 40/60 rs800292 0 0 6.00E-03 17194541 View
CFH Control 40/60 rs800292 0 0 6.00E-03 25612476 View
CFD AMD rs1651896 0 0 7.10E-01 25612476 View
CFH wet AMD 68±7.65 31/115 0 0 4.09E-01 21139680 View
CFH Control 60.2±16.2 53/52 0 0 4.09E-01 16710702 View
ROBO1 Control 75.40&&8.25 111/87 rs1387665 1.2 (0.98-.46) 7.40E-02 16710702 View
ROBO1 wet AMD 73.80&&7.77 209/143 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 Dry AMD 76.65&&2.32 69/37 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 Control 73.78&&7.25 113/100 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 wet AMD 76.33&&7.49 82/57 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
C3 Control 79.1±6.1 53/53 rs2230199 4.93 (1.98-2.25) 6.00E-04 23209669 View
ROBO1 Dry AMD 74.44&&7.99 37/31 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 Control 60.21&&5.9 691/379 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 wet AMD 61.07&&6.0 89/75 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
ROBO1 Dry AMD 59.53&&5.7 207/86 rs1387665 1.2 (0.98-.46) 7.40E-02 21998696 View
CFH AMD rs1061170 1.41 (0.75-.65) 7.00E-03 21998696 View
PLEKHA1 Control 71.8&&7.7 66/53 rs10887149 1.35 (0.95-.92) 7.40E-02 25811666 View
PLEKHA1 AMD 72.7&&7.4 255/147 rs10887149 1.35 (0.95-.92) 7.40E-02 20445115 View
PLEKHA1 Early AMD 70.3&&5.4 41/17 rs10887149 1.35 (0.95-.92) 7.40E-02 20445115 View
PLEKHA1 CNV 73.5&&7.5 186/109 rs10887149 1.35 (0.95-.92) 7.40E-02 20445115 View
PLEKHA1 Geographic Atrophy 70.8&&8.4 28/21 rs10887149 1.35 (0.95-.92) 7.40E-02 20445115 View
APOE AMD 73.26±9.24 190/144 rs429358 0 0 9.55E-01 33467888 View
APOE AMD rs7412 1 0 NA 23209669 View
CFH wet AMD 68.25±8.806 67/47 rs3753394 1.524 (1.074-.163) 7.00E-03 20445115 View
CFH Control 66.83±7.794 93/94 rs3753394 1.524 (1.074-.163) 7.00E-03 18223247 View
IL17A AMD 78.8±8.3 133/144 rs3748067 0.7 (0.42-.16) 1.59E-01 18223247 View
IL17A Control 66.4±10.7 94/68 rs3748067 0.7 (0.42-.16) 1.59E-01 26765636 View
IL17A AMD 79.2±5.0 176/121 rs3748067 0.7 (0.42-.16) 1.59E-01 26765636 View
IL17A Control 76.8±4.3 105/88 rs3748067 0.7 (0.42-.16) 1.59E-01 26765636 View
CFH AMD 73.3±9.1 73/46 rs1061170 2.24 (1.65-.47) 1.00E-05 26765636 View
CFH Control 71.7±9.7 101/51 rs1061170 2.24 (1.65-.47) 1.00E-05 20626361 View
GSTZ1 wet AMD 69.5±8.9 44/68 0.63 (0.35-1.12) 1.12E-01 20626361 View
GSTZ1 Control 63.2±9.4 44/68 0.63 (0.35-1.12) 1.12E-01 21948024 View
Early AMD 77.8±5.3 600/431 rs16851585 0.77 (0.69,0.86) 1.10E-02 21245410
CFH wet AMD 65.8±3.5 45/64 rs1410996 0 0 6.30E-01 21948024 View
CFH Control 64.1±3.2 76/74 rs1410996 0 0 6.30E-01 20538655 View
CFH AMD 69.2±8.7 125/219 rs529825 0 0 2.92E-05 20538655 View
CFH PCV 66.6±9.6 143/225 rs529825 0 0 2.92E-05 24692129 View
CFH Control 67.2±9.6 285/226 rs529825 0 0 2.92E-05 24692129 View
IL17A AMD 66.5±8.9 126/100 rs2275913 1.08 (0.67-.82) 5.82E-01 24692129 View
IL17A Control 67.6±9.2 126/106 rs2275913 1.08 (0.67-.82) 5.82E-01 25028103 View
CD36 PCV 73.8±7.5 44/166 rs10499862 0 0 6.60E-03 25028103 View
CD36 AMD 75.3±7.3 31/108 rs10499862 0 0 6.60E-03 22275803 View
CD36 Control 72.1±5.9 79/119 rs10499862 0 0 6.60E-03 22275803 View
Early AMD 62.3±5.5 199/200 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFH wet AMD 75.5±7.5 75/88 rs3753394 1.63 (1.22-2.19) 1.10E-03 22275803 View
CFH Control 73.5±6.5 130/114 rs3753394 1.63 (1.22-2.19) 1.10E-03 17167412 View
VEGFA AMD 69.5&&11.3 69/90 rs833061 1.39 (0.97-.00) 8.00E-02 17167412 View
VEGFA Control 72.9&&7.9 57/83 rs833061 1.39 (0.97-.00) 8.00E-02 20847577 View
CRP AMD 79.6±6.9 105/93 rs2808635 0.57 (0.25-.28) 1.71E-01 20847577 View
CRP AMD 78.4±8.3 40/35 rs2808635 0.57 (0.25-.28) 1.71E-01 19692124 View
VEGFA AMD rs1413711 3.3 (1.4-7.9) 6.00E-03 19692124 View
C2 Control 72.4±6.2 120/84 rs9332739 1.5 (0.76-.94) 2.40E-01 21881842 View
C2 AMD 73.4±7.8 382/183 rs9332739 1.5 (0.76-.94) 2.40E-01 18806293 View
SYN3 Control 73.9&&10.8 92/68 rs9621532 0.67 (0.32-.40) 2.83E-01 18806293 View
Early AMD 72.5±9.0 462/334 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
SYN3 AMD 79.0&&8.1 126/111 rs9621532 0.67 (0.32-.40) 2.83E-01 23422939 View
TF AMD 68.2 82/23 rs4481157 1.11 (0.66-1.85) 7.92E-01 23422939 View
TF Control 73.3 185/93 rs4481157 1.11 (0.66-1.85) 7.92E-01 21422745 View
CFH Advanced AMD 164/117 rs1061170 1.9 (1.4-2.6) <0.001 21422745 View
CFH Early AMD 713/472 rs1061170 1.9 (1.4-2.6) <0.001 17456821 View
HMOX2 AMD 72.5±8.5 182/94 rs1051308 1.16 (0.74-.83) 0.00E+00 17456821 View
HMOX2 Dry AMD 72.9±9.4 67/34 rs1051308 1.16 (0.74-.83) 0.00E+00 21804464 View
HMOX2 wet AMD 72.3±7.9 116/60 rs1051308 1.16 (0.74-.83) 0.00E+00 21804464 View
HMOX2 Control 68.3±10.9 82/23 rs1051308 1.16 (0.74-.83) 0.00E+00 21804464 View
SERPINF1 PCV 65&&8.45 60/117 rs1136287 1.004 (0.7296-.3810) 9.82E-01 21804464 View
Early AMD 80.0±4.7 162/96 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
SERPINF1 AMD 67&&9.46 47/84 rs1136287 1.004 (0.7296-.3810) 9.82E-01 22029535 View
SERPINF1 Control 68&&9.17 69/113 rs1136287 1.004 (0.7296-.3810) 9.82E-01 22029535 View
HTRA1 wet AMD 81.2±7.9 98/94 rs11200638 0 0 3.72E-10 22029535 View
HTRA1 wet AMD 78.9±12.1 132/146 rs11200638 0 0 3.72E-10 18206206 View
HTRA1 Geographic Atrophy 81.0±10.7 128/89 rs11200638 0 0 3.72E-10 18206206 View
HTRA1 Geographic Atrophy 78.3±12.7 32/32 rs11200638 0 0 3.72E-10 18206206 View
HTRA1 Control 74±12 104/104 rs11200638 0 0 3.72E-10 18206206 View
ARMS2 AMD rs2736911 0 0 6.46E-05 18206206 View
ARMS2 Control rs2736911 0 0 6.46E-05 20140183 View
ARMS2 AMD rs2736911 0 0 6.46E-05 20140183 View
Early AMD 75.1±7.7 626/438 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
ARMS2 Control rs2736911 0 0 6.46E-05 20140183 View
ARMS2 AMD rs2736911 0 0 6.46E-05 20140183 View
ARMS2 Control rs2736911 0 0 6.46E-05 20140183 View
Geographic Atrophy 97.83±1.86 rs7624556 0 0 1.25E-06 20140183
Control 98.89±2.74 rs7624556 0 0 1.25E-06 26782385
ARMS2/LOC387715 Control 153/127 rs10490924 3 (2.1-.3) <0.001 26782385
ARMS2/LOC387715 Geographic Atrophy 79/68 rs10490924 3 (2.1-.3) <0.001 17347568
ARMS2/LOC387715 CNV 142/99 rs10490924 3 (2.1-.3) <0.001 17347568
ARMS2/LOC387715 Advanced AMD 87/55 rs10490924 3 (2.1-.3) <0.001 17347568
ARMS2 Control 61.7±9.2 106/51 rs2736911 0.9 (0.53-1.5) 7.73E-01 17347568 View
Early AMD 69.8±9.0 104/105 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
ARMS2 Early AMD 61.6±8.2 119/39 rs2736911 0.9 (0.53-1.5) 7.73E-01 23687431 View
CFH AMD rs529825 2.67 (2.22-.12) <0.0001 23687431 View
CD36 AMD 76±7.3 22/87 rs12531609 0.69 (0.45-1.07) 9.45E-02 18043728 View
CD36 Control 72±5.8 72/110 rs12531609 0.69 (0.45-1.07) 9.45E-02 20157514 View
CFH AMD rs1061170 4.4 (2.3-.5) <0.0001 20157514 View
CFH Control rs1061170 4.4 (2.3-.5) <0.0001 16877387 View
ADIPOQ Advanced AMD 64.7±7.8 101/88 rs710445 1.01 (0.75-.35) 9.51E-01 16877387 View
ADIPOQ Control 65.3±6.4 100/68 rs710445 1.01 (0.75-.35) 9.51E-01 26301885 View
ERCC6 AMD rs3793784 1.51 (1.07-.11) 2.00E-02 26301885 View
CFHR5 AMD 69.1±9.3 174/79 rs10922152 0 0 2.90E-03 1675484 View
Early AMD 59.8±8.0 41/27 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFHR5 Control 65.4±9.9 175/117 rs10922152 0 0 2.90E-03 16998489 View
SIRT1 AMD rs12778366 0.837 (0.565-1.238) 3.72E-01 16998489 View
GSTM1 AMD 1.44 (0.69-.00) 3.33E-01 26656366
PPARGC1A Control 76.6&&0.23 58/456 rs3774923 0.52 (0.33-.83) 6.00E-03 16496253 View
PPARGC1A wet AMD 80.4&&0.30 63/443 rs3774923 0.52 (0.33-.83) 6.00E-03 View
PPARGC1A Control 76.2&&0.34 55/143 rs3774923 0.52 (0.33-.83) 6.00E-03 View
PPARGC1A wet AMD 77.5&&0.64 58/65 rs3774923 0.52 (0.33-.83) 6.00E-03 View
PPARGC1A Control 73.7&&0.34 53/265 rs3774923 0.52 (0.33-.83) 6.00E-03 View
PPARGC1A wet AMD 79.7&&0.55 65/140 rs3774923 0.52 (0.33-.83) 6.00E-03 View
ELOVL4 AMD 73.32±9.93 0 0 1.40E-01
Early AMD 66.1±10.0 44/79 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
ELOVL4 Control 69.85±8.8 0 0 1.40E-01 11803489
TLR3 AMD 64.97&&7.1 40/75 rs3775291 1.13 (0.660-.936) 6.55E-01 11803489 View
TLR3 Control 60.38&&13.2 21/40 rs3775291 1.13 (0.660-.936) 6.55E-01 24682730 View
Paraoxonase wet AMD 71.1&&8.1 25/47 0 0 3.23E-02 24682730
Paraoxonase Control 70.6&&8.3 50/90 0 0 3.23E-02 11476678
CFH AMD rs10922105 0 0 1.00E-27 11476678 View
GSTT1 AMD 75±8 67/53 0.76 (0.42-.37) 0.00E+00 16936733
GSTT1 Control 73±10 109/89 0.76 (0.42-.37) 0.00E+00 21212706
ARMS2/LOC387715 Control 72±9 183/146 rs10490924 2.87 (1.91-.30) 3.40E-07 26617902
Early AMD 64.9±10.6 57/84 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
ARMS2/LOC387715 AMD 79±5 229/170 rs10490924 2.87 (1.91-.30) 3.40E-07 17325155
SOD2 AMD 74.9&&7.0 90/114 rs2842992 0.87 (0.67-1.13) 2.77E-01 17325155 View
SOD2 Control 67.6&&6.6 215/169 rs2842992 0.87 (0.67-1.13) 2.77E-01 24667176 View
CFH wet AMD 68.7±10.3 56/80 rs3753394 1.31 (0.62-.78) 5.00E-02 24667176 View
CFH Control 72.9±7.9 57/83 rs3753394 1.31 (0.62-.78) 5.00E-02 21111031 View
CFH Control 72.6±6.7 104/125 rs1061170 3.56 (2.03-6.25) 9.80E-06 21111031 View
CFH AMD 76.1±7.5 98/168 rs1061170 3.56 (2.03-6.25) 9.80E-06 27316788 View
CFH wet AMD 74.6±7.6 63/109 rs1061170 3.56 (2.03-6.25) 9.80E-06 27316788 View
CFH Dry AMD 79.5±5.9 35/59 rs1061170 3.56 (2.03-6.25) 9.80E-06 27316788 View
VEGFA AMD 70.6&&8.4 110/90 rs3025039 0.87 (0.57-1.33) 0.00E+00 27316788 View
APOE Control 65.3±9.89 194/177 rs429358 0 0 9.55E-01 33467888 View
Advanced AMD 77.8±5.3 95/66 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
VEGFA Control 70.5&&8.3 106/94 rs3025039 0.87 (0.57-1.33) 0.00E+00 23569009 View
CNP147 CNV 79.2±7.1 181/116 1 0 0.00E+00 23569009
CNP147 AMD 77.1±7.4 214/162 1 0 0.00E+00 21856016
OR52B4 AMD rs4910623 3.14 0 3.69E-09 21856016 View
CCL2 AMD 0.15 0 0.00E+00 27892514 View
MMP2 AMD 63 107/41 rs2285053 0.102 0 0.00E+00 18172114 View
MMP2 Control 67 389/137 rs2285053 0.102 0 0.00E+00 24079541 View
VEGFA AMD rs1413711 0 0 1.00E-03 24079541 View
VEGFA AMD 73.9&&8.8 22/16 rs1413711 0 0 <0.0001 17438519 View
VEGFA AMD 74.3&&8.7 17/21 rs1413711 0 0 <0.0001 24157918 View
Advanced AMD 65.2±5.6 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
VEGFA AMD 73.1&&8.0 rs1413711 0 0 <0.0001 24157918 View
HTRA1 Dry AMD 71.1±7.5 23/30 rs11200638 1.99 (0.66-.01) 5.60E-04 24157918 View
HTRA1 wet AMD 71.4±6.4 18/25 rs11200638 1.99 (0.66-.01) 5.60E-04 23112570 View
HTRA1 AMD 71.2±7.1 41/54 rs11200638 1.99 (0.66-.01) 5.60E-04 23112570 View
HTRA1 Control 71.5±6.9 41/49 rs11200638 1.99 (0.66-.01) 5.60E-04 23112570 View
HTRA1 AMD rs11200638 7.75 (2.45-4.47) 5.60E-04 23112570 View
CFH wet AMD 77.6±6.9 109/70 rs1061170 4.57 (2.63-.94) <0.001 18301036 View
CFH Control 77.5±6.4 92/71 rs1061170 4.57 (2.63-.94) <0.001 17398321 View
HLA-II AMD 79.7±3.1 456/ 0.96 (0.71-.29) 7.70E-01 17398321
HLA-II Control 78.0±2.7 499/ 0.96 (0.71-.29) 7.70E-01 25665771
Advanced AMD 79.5±9.2 50/32 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
C3 AMD 70.6±8.2 58/65 rs10411506 1.16 (0.86-.57) 3.20E-01 25665771 View
C3 Control 69.2±10.1 61/69 rs10411506 1.16 (0.86-.57) 3.20E-01 19899988 View
OGG1 AMD 68.29&&10.95 82/23 rs1052133 0.51 (0.31-0.81) 1.00E-02 19899988 View
OGG1 Control 72.46&&8.51 179/92 rs1052133 0.51 (0.31-0.81) 1.00E-02 22469746 View
CFH wet AMD 74.0±9.4 55/26 rs1061170 0 0 <0.0001 22469746 View
CFH AMD 74.9±5.7 32/28 rs1061170 0 0 <0.0001 16379025 View
CFH wet AMD 74.3±8.0 87/54 rs1061170 0 0 <0.0001 16379025 View
CFH Control 74.6±6.3 53/38 rs1061170 0 0 <0.0001 16379025 View
CFH AMD 68.3±8.5 836/552 rs1061170 0 0 <0.0001 16379025 View
CFH Control 78.8±7.4 326/161 rs1061170 0 0 <0.0001 22977134 View
Advanced AMD 82.3±4.6 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
TF AMD 70.9&&9.1 323/170 rs4481157 0.78 (0.47-1.29) <0.05 22977134 View
TF wet AMD 70.6&&8.6 205/106 rs4481157 0.78 (0.47-1.29) <0.05 23089144 View
TF Dry AMD 71.4&&10.0 120/62 rs4481157 0.78 (0.47-1.29) <0.05 23089144 View
TF Control 68.9&&10.2 113/58 rs4481157 0.78 (0.47-1.29) <0.05 23089144 View
KDR AMD 76.8±7.5 202/164 rs4576072 0 0 4.00E-03 23089144 View
C3 Control 69.5±8.3 221/78 rs11569536 0 0 2.00E-02 24365177 View
C3 AMD 77.2±9.2 rs11569536 0 0 2.00E-02 17568988 View
C3 Early AMD 74.5±9.8 rs11569536 0 0 2.00E-02 17568988 View
C3 wet AMD 79.2±8.8 rs11569536 0 0 2.00E-02 17568988 View
C3 Geographic Atrophy 79.9±6.6 rs11569536 0 0 2.00E-02 17568988 View
Advanced AMD 79.9±7.0 124/83 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
HTRA1 AMD rs11200638 2.23 (1.57-.18) 7.75E-06 17568988 View
CFH AMD rs800292 0.48 (0.34-.66) 8.63E-06 17962488 View
MMP2 wet AMD 75.40&&7.65 168/99 rs243865 0 0 2.87E-01 19365580 View
MMP2 Control 74.78&&8.42 205/113 rs243865 0 0 2.87E-01 29582818 View
GSTP1 Control 65.8±6.7 69/69 rs1695 0 0 7.00E-03 29582818 View
GSTP1 wet AMD 66.2±8.5 51/80 rs1695 0 0 7.00E-03 22487578 View
CFH wet AMD 69 34/41 rs1061170 0 0 7.73E-01 22487578 View
CST3 wet AMD 80.1 224/126 rs1064039 1.07 (0.84-.36) 5.80E-01 23204795 View
CFH AMD rs1061170 1.2 (0.90-.56) 1.00E-01 25893795 View
Advanced AMD 78.7±9.1 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CR1 PCV 67.7±9.04 64/130 rs2274567 1.69 (1.28-.40) 1.06E-04 17198853 View
CR1 CNV 74.9±7.8 60/95 rs2274567 1.69 (1.28-.40) 1.06E-04 30026504 View
CR1 Control 68.5±9.0 488/763 rs2274567 1.69 (1.28-.40) 1.06E-04 30026504 View
CFHR3 AMD 76.3±9.3 169/83 7.69 (1.75-3.3) 1.10E-05 24367156
CFHR3 Early AMD 74.4±9.7 100/47 7.69 (1.75-3.3) 1.10E-05 19553609
CFHR3 wet AMD 79.1±8.6 49/20 7.69 (1.75-3.3) 1.10E-05 19553609
CFHR3 Geographic Atrophy 78.9±7.4 23/13 7.69 (1.75-3.3) 1.10E-05 19553609
CFHR3 AMD 7.69 (1.75-3.3) 1.10E-05 19553609
CFB AMD 67.5±9.6 186/304 rs541862 0.84 (0.55-.27)) 4.10E-01 19553609 View
Advanced AMD 75.8±10.9 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFB PCV 64.8±9.7 125/294 rs541862 0.84 (0.55-.27)) 4.10E-01 26861912 View
CFB Control 71.8±5.5 599/717 rs541862 0.84 (0.55-.27)) 4.10E-01 26861912 View
HMCN1 AMD rs10911825 0 0 3.50E-02 26861912 View
CFH wet AMD 74.9±7.4 50/89 rs800292 0 0 3.00E-03 17216616 View
CFH Control 72.6±6.4 50/73 rs800292 0 0 3.00E-03 27778189 View
CFH AMD 79.8±8.0 118/70 rs1061170 2.1 (1.3-3.3) 0.00E+00 27778189 View
CFH Control 69.5±9.5 115/74 rs1061170 2.1 (1.3-3.3) 0.00E+00 17631852 View
MMP2 Control 72.94&&4.47 50/50 rs2285053 0.98 (0.60-1.60) 9.33E-01 17631852 View
MMP2 wet AMD 69.29&&5.55 47/53 rs2285053 0.98 (0.60-1.60) 9.33E-01 30289322 View
MMP2 Dry AMD 69.98&&4.94 50/50 rs2285053 0.98 (0.60-1.60) 9.33E-01 30289322 View
Advanced AMD 72.1±7.1 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
CFH AMD 69.87±8.61 42/53 rs1061170 2.32 (1.23-.35) 9.00E-03 30289322 View
CFH Control 68.89±8.35 47/50 rs1061170 2.32 (1.23-.35) 9.00E-03 22486323 View
PON1 Control 66.6&&7.31 70/68 rs854560 0 0 8.70E-02 22486323 View
PON1 AMD 67.1&&8.22 68/74 rs854560 0 0 8.70E-02 23538572 View
CCL2 Control 72.2±6.4 50/93 rs1024611 0.86 (0.53-1.39) 5.36E-01 23538572 View
CCL2 AMD 75.4±7.4 68/87 rs1024611 0.86 (0.53-1.39) 5.36E-01 26940485 View
CFH AMD rs1061170 2.3 (1.6-.3) <0.001 26940485 View
mtDNA CNV 77.2&&8.4 0 0 0.00E+00 26045836
mtDNA Dry AMD 80.9&&6.0 0 0 0.00E+00 22348027
Advanced AMD 67.5±10.4 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
mtDNA Control 73.6&&9.5 0 0 0.00E+00 22348027
AGER Early AMD 71.88±10.3 98/202 rs1800624 0 0 1.69E-01 18704199 View
AGER wet AMD 75.5±7.7 186/114 rs1800624 0 0 1.69E-01 29317590 View
AGER Control 50.83±14.1 518/282 rs1800624 0 0 1.69E-01 29317590 View
NRP1 AMD 77.11&&7.46 215/162 rs2229935 0.1 (0.000-.301) 0.00E+00 29317590 View
CFH AMD rs1061170 2.22 (1.23-.00) 1.00E-04 26426212 View
IL6 Control 63.0±0.84 45/55 rs1800795 0 0 1.00E-04 21790300 View
IL6 AMD 70.0±1.07 27/63 rs1800795 0 0 1.00E-04 26330749 View
C3 AMD 0 0 1.40E-02 26330749 View
Control 74.9±5.0 987/756 rs16851585 0.77 (0.69,0.86) 1.10E-02 23326517
MMP2 AMD 67.1&&6.9 65/79 rs243865 0 0 5.10E-02 18325906 View
MMP2 Control 66.1&&6.5 88/84 rs243865 0 0 5.10E-02 23536957 View
CFI AMD rs141853578 11.38 (1.49-87.06) 3.00E-03 23536957 View
C2 AMD rs9332739 0.66 (0.34-.30) 2.23E-01 26767664 View
CFI Early AMD 73 217/92 rs10033900 0 0 1.22E-01 19696172 View
CFI wet AMD 76 195/106 rs10033900 0 0 1.22E-01 31583032 View
CFI Control 71 211/95 rs10033900 0 0 1.22E-01 31583032 View
VEGFA PCV 65&&8.61 84/167 rs833069 1.16 (0.88-1.51) 2.91E-01 31583032 View
VEGFA AMD 67&&9.21 56/101 rs833069 1.16 (0.88-1.51) 2.91E-01 24303777 View
VEGFA Control 69&&9.00 80/124 rs833069 1.16 (0.88-1.51) 2.91E-01 24303777 View

Institutes for Systems Genetics, West China Hospital
     Copyright @ 2023 ISG. All Rights Reserved.