Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-630
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
CDC14A
Cancer name
Glioma
Cancer site
Brain, Central Nervous System
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
Inhibition of miR-630 enhances the cell resistance to radiation
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Our data indicate that anti-miR-630 enhances the radio-resistance of human glioma cells by targeting CDC14A, implying that miR-630 may act as a novel therapeutic target for enhancing the radiation efficiency on glioma patients.
Tissue resource
human glioma cell lines BT325
human glioma cell lines U373
human glioma cell lines U87
human glioma cell lines U251
Experiment
qRT-PCR,Western blot
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.