Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-20a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
iASPP
Downstream target
FBXL5/BTG3
Cancer name
Cervical Cancer
Cancer site
Cervix Uteri
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Overexpression of miR-20a significantly decreased the activity of cisplatin by restoring cell survival.
Tissue resource
pairs of primary CC specimens and adjacent non-tumor cervical tissues
cervical cancer cell lines HeLa
cervical cancer cell lines SiHa
human embryonic kidney cell lines HEK-293T
human normal endometrial epithelial cell lines EM
Experiment
qRT-PCR,Western blot
Institute
Sun Yat-Sen University Cancer Center
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.