hsa-miR-340-5p

ncRNA information

ncRNA name

hsa-miR-340-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

LPAATĪ²

Cancer information

Cancer name

Osteosarcoma

Cancer site

Bone, Articular Cartilage

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Our data indicated that miR-340-5p enhanced the sensitivity to CDDP by targeting LPAATĪ².

Tissue resource

osteosarcoma cell lines MG-63

osteosarcoma cell lines Saos-2

osteosarcoma cisplatin-resistant cell lines MG-63/CDDP

osteosarcoma cisplatin-resistant cell lines Saos-2/CDDP

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Shanghai Cell Institute

Country

China

Continent

Asia