Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CRNDE
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
p21
Cancer name
Lung Adenocarcinoma
Cancer site
Lung
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
66
Male patients
44
Female patients
22
Age range and number
30(<60)+36(>=60)
PMID
Description
In conclusion, our data suggest that CRNDE may function as an oncogene by modulating p21, finally contributing to the radioresistant phenotype formation of LAD cells.
Tissue resource
lung adenocarcinoma specimens and adjacent nontumor specimens
human lung cancer cell lines A549
human lung cancer cell lines H1299
lung adenocarcinoma specimens and adjacent nontumor specimens
human lung cancer cell lines A549
human lung cancer cell lines H1299
Experiment
qRT-PCR,Western blot
Institute
Tumor Hospital of Yunnan Province,the Third Affiliated Hospital of Kunming Medical University
the Keygen Biotech
the Keygen Biotech
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.