hsa-miR-1290

ncRNA information

ncRNA name

hsa-miR-1290

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

hMSH2

Cancer information

Cancer name

Colon Cancer

Cancer site

Colon, Rectum, and Anus

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-1290 Promotes Resistance to 5-Fluorouracil by Directly Targeting hMSH2.

Tissue resource

human colon cancer tissues

human colon cancer cell lines RKO

human colon cancer cell lines SW480

human colon cancer cell lines HCT116

human colon cancer cell lines LoVo

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

General Surgery Department of Shanghai General Hospital

the Type Culture Collection of the Chinese Academy of Sciences

Country

China

Continent

Asia