Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
ROR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Tamoxifen
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
These results indicate that inhibition of long noncoding RNA ROR reverses resistance to Tamoxifen by inducing autophagy in breast cancer.
Tissue resource
breast cancer tissues and its adjacent normal tissues
breast cancer cell lines MCF7
breast cancer cell lines BT474
breast cancer cell lines MDA-MB-435
breast cancer cell lines MDA-MB-231
breast cancer cell lines MCF10A
Experiment
qRT-PCR,Western blot
Institute
the First Affiliated Hospital, University of South China
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.