Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
FGD5-AS1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-153-3p/TWF1
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
22
Male patients
10
Female patients
12(<=55)+20(>55)
Age range and number
Not available
PMID
Description
Our study exhibited that FGD5-AS1 promoted DDP resistance through modulating the miR-153-3p/TWF1 axis in HCC cells
Tissue resource
cisplatin-resistant and cisplatin-sensitive hepatocellular carcinoma tissues
human hepatocellular carcinoma cell lines Huh7
human hepatocellular carcinoma cell lines Hep3B
Experiment
32
Institute
the Third Affiliated Hospital of Soochow University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.