CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-125b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Trastuzumab

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

38

Male patients

21

Female patients

17

Age range and number

Not available

Research information

PMID

28672982

Description

The present study indicated that the increased miR-125b level was significantly associated with trastuzumab resistance in HER2-positive gastric cancer (P<0.05).

Tissue resource

gastric cancer and non-cancerous tissues

Experiment

qRT-PCR

Institute

the Yuhuangding Hospital

Country

China

Continent

Asia