Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-218
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
PPP2R5A/Wnt signaling pathway
Cancer name
Oral Cancer
Cancer site
Lip, Oral Cavity
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MicroRNA-218 promotes cisplatin resistance in oral cancer via the PPP2R5A/Wnt signaling pathway.
Tissue resource
human oral cancer tissues
human oral cancer cell lines UM1
human oral cancer cell lines UM2
human oral cancer cell lines Cal27
human oral cancer cell lines MD1386
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
The Affiliated Stomatological Hospital of Sun Yat-sen University
University of Illinois
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.