hsa-miR-218

ncRNA information

ncRNA name

hsa-miR-218

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

PPP2R5A/Wnt signaling pathway

Cancer information

Cancer name

Oral Cancer

Cancer site

Lip, Oral Cavity

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-218 promotes cisplatin resistance in oral cancer via the PPP2R5A/Wnt signaling pathway.

Tissue resource

human oral cancer tissues

human oral cancer cell lines UM1

human oral cancer cell lines UM2

human oral cancer cell lines Cal27

human oral cancer cell lines MD1386

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

The Affiliated Stomatological Hospital of Sun Yat-sen University

University of Illinois

Country

China

USA

Continent

Asia

Amercia