CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-26b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Wee1

Cancer information

Cancer name

Glioblastoma

Cancer site

Brain, Central Nervous System

Treatment information

Treatment type

Chemotherapy

Drug

Temozolomide

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

28898169

Description

Notably, overexpression of miR-26b sensitized TR cells to TMZ.

Tissue resource

human glioma cancer cell lines SNB19

human glioma cancer temozolomide-resistant cell lines SNB19 TR

human glioma cancer cell lines T98G

human glioma cancer temozolomide-resistant cell lines T98G TR

Experiment

qRT-PCR,Western blot

Institute

Country

Continent