Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MIR100HG
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-100/miR-125b
Cancer name
Colorectal Cancer
Cancer site
Colon, Rectum, and Anus
Treatment type
Chemotherapy
Drug
Cetuximab
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-100 and miR-125b cooperativity drives cetuximab resistance.
Tissue resource
colorectal cancer cell lines NCI-H508
colorectal cancer cell lines Caco-2
colorectal cancer cell lines SW403
colorectal cancer cell lines SW948
colorectal cancer cell lines HT29
colorectal cancer cell lines SK-CO-1
colorectal cancer cell lines DLD-1
colorectal cancer cell lines SW480
colorectal cancer cell lines SW837
colorectal cancer cell lines SW48
colorectal cancer cell lines SW620
colorectal cancer cell lines LoVo
colorectal cancer cell lines COLO205
colorectal cancer cell lines T84
colorectal cancer cell lines LS174T
colorectal cancer cell lines NCI-H716
colorectal cancer cell lines HCT8
colorectal cancer cell lines HCT15
colorectal cancer cell lines SW1116
colorectal cancer cell lines RKO
colorectal cancer cell lines COLO320DM
colorectal cancer cell lines HuTu80
colorectal cancer cell lines LS123
colorectal cancer cell lines HCT116
colorectal cancer cell lines SNUC4
colorectal cancer cell lines V9P
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
American Type Culture Collection
the Korean Cell Line Bank
Country
USA
Korea
Continent
North American
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.