hsa-miR-103

ncRNA information

ncRNA name

hsa-miR-103

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

COP1

Cancer information

Cancer name

Leukemia

Cancer site

Leukemia

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

29058777

Description

Overexpression of miR-103 increased K562 cells drug resistance via promoting cell viability and cell cycle-related factors expressions.

Tissue resource

human leukemia cell lines K562

human leukemia cell lines KASUMI

Experiment

qRT-PCR,Western blot

Institute

American Type Culture Collection

Country

USA

Continent

North American

Institutes for Systems Genetics, West China Hospital
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