Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-323
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
p73
Cancer name
Prostate Cancer
Cancer site
Prostate
Treatment type
Chemotherapy
Drug
Docetaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MicroRNA-323 upregulation promotes prostate cancer growth and docetaxel resistance by repressing p73.
Tissue resource
human prostate cancer cell lines PC-3
human prostate cancer cell lines DU145
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.