Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-139-5p
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Prognosis
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer via its regulation of genes involved in multiple DNA repair and reactive oxygen species defense pathways.
Tissue resource
primary breast tumor specimens
Experiment
qRT-PCR,Luciferase reporter assay
Institute
the St. George Hospital
Country
Australia
Continent
Oceania
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.