Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LBX2-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Colorectal Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
13-Fluorouracil
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
148
Male patients
117
Female patients
76(<60)+189(>=60)
Age range and number
Not available
PMID
Description
LncRNA LBX2-AS1 promotes colorectal cancer progression and 5-fluorouracil resistance
Tissue resource
colorectal cancer tissues were utilized from patients
colorectal cancer cell lines HCT116
colorectal cancer cell lines SW480
Experiment
265
Institute
Changhai hospital
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.