Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-199a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
YES1
Cancer name
Prostate Cancer
Cancer site
Prostate
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Down
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
He downregulation of miR-199a contributes to PTX resistance in prostate cancer.
Tissue resource
normal prostate and prostate cancer specimens
prostate cancer cell lines PC3
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
Shanghai University of Traditional Chinese Medicine Affiliated LONGHUA Hospital
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.