Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-149
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
P-gp
Cancer name
Malignant Mesothelioma
Cancer site
Skin
Treatment type
Chemotherapy
Drug
Taxane
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiRNA149, contributes to the development of MDR within malignant mesothelioma cells by regulating the expression of MDR1.
Tissue resource
human mesothelioma cell lines MSTO-211H
human malignant melanoma cell lines A-375
human carcinoma lung cell lines A549
human carcinoma lung cell lines H69AR
Experiment
qRT-PCR,Western blot
Institute
American Type Culture Collection
Country
USA
Continent
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.